
Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target

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Lead Product(s) : MT-125
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Mayo Clinic
Deal Size : Inapplicable
Deal Type : Inapplicable
A Phase 1 Study of the Safety and Tolerability of MT-125 in GBM Patients
Details : MT-125 is a Small Molecule drug candidate drug candidate, which is currently being evaluated in Phase I clinical studies for the treatment of Glioblastoma.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
September 22, 2025
Lead Product(s) : MT-125
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Mayo Clinic
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : MT-125
Therapeutic Area : Oncology
Study Phase : IND Enabling
Sponsor : National Cancer Institute
Deal Size : $4.5 million
Deal Type : Funding
Myosin Awarded $4.5 Million NCI Bridge Grant to Advance Phase I of MT-125 in Glioblastoma
Details : The funding will support Phase I dose escalation and expansion trial of MT-125, a first-in-class novel small molecule therapeutic being evaluated in patients with glioblastoma.
Product Name : MT-125
Product Type : Miscellaneous
Upfront Cash : Undisclosed
August 19, 2025
Lead Product(s) : MT-125
Therapeutic Area : Oncology
Highest Development Status : IND Enabling
Sponsor : National Cancer Institute
Deal Size : $4.5 million
Deal Type : Funding

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Lead Product(s) : MT-125
Therapeutic Area : Oncology
Study Phase : IND Enabling
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Myosin Receives FDA Clearance to Initiate First-in-Human Trial of MT-125 in Glioblastoma
Details : MT-125 is a selective inhibitor of non-muscle myosin II (NMII), designed to disrupt critical mechanisms of glioblastoma progression.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
June 09, 2025
Lead Product(s) : MT-125
Therapeutic Area : Oncology
Highest Development Status : IND Enabling
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : MT-110
Therapeutic Area : Psychiatry/Psychology
Study Phase : IND Enabling
Sponsor : National Institute on Drug Abuse
Deal Size : $3.0 million
Deal Type : Funding
Myosin gets $3M NIH Grant to Advance MT-110 Trial for Meth use Disorder
Details : The grant will help support the initiation of a Phase 1 clinical trial to assess the safety, tolerability of MT-110, as a first-in-class treatment option for methamphetamine use disorder.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Undisclosed
April 28, 2025
Lead Product(s) : MT-110
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : IND Enabling
Sponsor : National Institute on Drug Abuse
Deal Size : $3.0 million
Deal Type : Funding

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Lead Product(s) : MT-125
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : DeepWork Capital
Deal Size : $52.5 million
Deal Type : Financing
Myosin Closes Seed Round to Advance Cancer & Neuroscience Clinical Trials
Details : The company intends to advance its lead compound, MT-125, which targets a molecular nanomotor, to treat glioblastoma, the most aggressive brain cancer.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Undisclosed
March 03, 2025
Lead Product(s) : MT-125
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : DeepWork Capital
Deal Size : $52.5 million
Deal Type : Financing

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Lead Product(s) : MT-125
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Mint12 Pharma
Deal Size : Undisclosed
Deal Type : Financing
Details : Myosin Therapeutics will use the financing to advance and develop MT-125, to treat glioblastoma, which is a highly aggressive form of brain cancer with a 95% fatality rate and limited treatment options available.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Undisclosed
March 14, 2023
Lead Product(s) : MT-125
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Mint12 Pharma
Deal Size : Undisclosed
Deal Type : Financing

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