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    [{"orgOrder":0,"company":"Mural Oncology","sponsor":"XOMA","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Protein","year":"2025","type":"Acquisition","leadProduct":"MURA-8518","moa":"IL-18 receptor","graph1":"Oncology","graph2":"Preclinical","graph3":"Mural Oncology","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Mural Oncology \/ XOMA","highestDevelopmentStatusID":"4","companyTruncated":"Mural Oncology \/ XOMA"},{"orgOrder":0,"company":"Mural Oncology","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Protein","year":"2016","type":"Inapplicable","leadProduct":"ALKS 4230","moa":"IL-2 receptor","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Mural Oncology","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Infusion","sponsorNew":"Mural Oncology \/ Undisclosed","highestDevelopmentStatusID":"7","companyTruncated":"Mural Oncology \/ Undisclosed"},{"orgOrder":0,"company":"Mural Oncology","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Protein","year":"2019","type":"Inapplicable","leadProduct":"ALKS 4230","moa":"IL-2 receptor","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Mural Oncology","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Injection","sponsorNew":"Mural Oncology \/ Undisclosed","highestDevelopmentStatusID":"7","companyTruncated":"Mural Oncology \/ Undisclosed"},{"orgOrder":0,"company":"Mural Oncology","sponsor":"Alkermes Plc","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Protein","year":"2024","type":"Inapplicable","leadProduct":"Nemvaleukin Alpha","moa":"||IL-2-alpha receptor","graph1":"Oncology","graph2":"Phase III","graph3":"Mural Oncology","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Infusion","sponsorNew":"Mural Oncology \/ Alkermes Plc","highestDevelopmentStatusID":"10","companyTruncated":"Mural Oncology \/ Alkermes Plc"},{"orgOrder":0,"company":"Mural Oncology","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Protein","year":"2025","type":"Inapplicable","leadProduct":"Nemvaleukin Alpha","moa":"||IL-2-alpha receptor","graph1":"Oncology","graph2":"Phase III","graph3":"Mural Oncology","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Infusion","sponsorNew":"Mural Oncology \/ Undisclosed","highestDevelopmentStatusID":"10","companyTruncated":"Mural Oncology \/ Undisclosed"},{"orgOrder":0,"company":"Mural Oncology","sponsor":"Merck & Co","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Protein","year":"2021","type":"Inapplicable","leadProduct":"Nemvaleukin Alfa","moa":"IL2RA","graph1":"Oncology","graph2":"Phase III","graph3":"Mural Oncology","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Infusion","sponsorNew":"Mural Oncology \/ Merck & Co","highestDevelopmentStatusID":"10","companyTruncated":"Mural Oncology \/ Merck & Co"},{"orgOrder":0,"company":"Mural Oncology","sponsor":"Immune Oncology Network","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Protein","year":"2019","type":"Inapplicable","leadProduct":"Nemvaleukin Alfa","moa":"IL2RA","graph1":"Oncology","graph2":"Phase II","graph3":"Mural Oncology","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Infusion","sponsorNew":"Mural Oncology \/ Immune Oncology Network","highestDevelopmentStatusID":"8","companyTruncated":"Mural Oncology \/ Immune Oncology Network"},{"orgOrder":0,"company":"Mural Oncology","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Protein","year":"2020","type":"Inapplicable","leadProduct":"Nemvaleukin Alfa","moa":"IL2RA","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Mural Oncology","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Infusion","sponsorNew":"Mural Oncology \/ Undisclosed","highestDevelopmentStatusID":"7","companyTruncated":"Mural Oncology \/ Undisclosed"},{"orgOrder":0,"company":"Mural Oncology","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Protein","year":"2021","type":"Inapplicable","leadProduct":"Nemvaleukin Alfa","moa":"IL2RA","graph1":"Oncology","graph2":"Phase II","graph3":"Mural Oncology","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Injection","sponsorNew":"Mural Oncology \/ Undisclosed","highestDevelopmentStatusID":"8","companyTruncated":"Mural Oncology \/ Undisclosed"}]

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                            01

                            Mural Oncology

                            U.S.A arrow
                            AIChE Annual Meeting
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                            Mural Oncology

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                            AIChE Annual Meeting
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                            Lead Product(s) : MURA-8518

                            Therapeutic Area : Oncology

                            Study Phase : Preclinical

                            Sponsor : XOMA

                            Deal Size : Undisclosed

                            Deal Type : Acquisition

                            DEALS_DEV arrow-down

                            Mural Oncology Announces Entry into Agreement to be Acquired by XRA 5 Corp

                            Details : XOMA intends to redeploy, monetize, or otherwise dispose of nearly all of Mural’s assets, including its clinical and preclinical programs, including MURA-8518, a binding protein-resistant IL-18.

                            Product Name : MURA-8518

                            Product Type : Protein

                            Upfront Cash : Undisclosed

                            August 20, 2025

                            Lead Product(s) : MURA-8518

                            Therapeutic Area : Oncology

                            Highest Development Status : Preclinical

                            Sponsor : XOMA

                            Deal Size : Undisclosed

                            Deal Type : Acquisition

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                            02

                            Mural Oncology

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                            AIChE Annual Meeting
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                            Mural Oncology

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                            AIChE Annual Meeting
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                            Lead Product(s) : Nemvaleukin Alpha,Pembrolizumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Mural Updates Phase 3 ARTISTRY-7 Trial of Nemvaleukin with KEYTRUDA

                            Details : ALKS 4230 (nemvaleukin alfa) is an IL-2R agonist protein candidate, which is currently being evaluated for the treatment of platinum-resistant ovarian cancer.

                            Product Name : Undisclosed

                            Product Type : Protein

                            Upfront Cash : Inapplicable

                            March 25, 2025

                            Lead Product(s) : Nemvaleukin Alpha,Pembrolizumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

                            Mural Oncology

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                            AIChE Annual Meeting
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                            Mural Oncology

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                            AIChE Annual Meeting
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                            Lead Product(s) : Nemvaleukin Alpha,Pembrolizumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Sponsor : Alkermes Plc

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Mural Oncology Announces Enhancements to Late-Stage Clinical Trials

                            Details : Nemvaleukin is a IL-2 variant designed to harness anti-cancer capabilities of high-dose rhIL-2, currently in phase 3 clinical development for treating platinum-resistant epithelial ovarian cancer.

                            Product Name : Undisclosed

                            Product Type : Protein

                            Upfront Cash : Inapplicable

                            January 08, 2024

                            Lead Product(s) : Nemvaleukin Alpha,Pembrolizumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : Alkermes Plc

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            04

                            Mural Oncology

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                            AIChE Annual Meeting
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                            Mural Oncology

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                            AIChE Annual Meeting
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                            Lead Product(s) : Nemvaleukin Alfa

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Sponsor : Merck & Co

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Phase 3 Study of Nemvaleukin Alfa in Combination With Pembrolizumab in Patients With Platinum-Resistant Epithe...

                            Details : Nemvaleukin Alfa is a Protein drug candidate, which is currently being evaluated in phase III clinical studies for the treatment of Ovarian Neoplasms.

                            Product Name : Undisclosed

                            Product Type : Protein

                            Upfront Cash : Inapplicable

                            October 25, 2021

                            Lead Product(s) : Nemvaleukin Alfa

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : Merck & Co

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            05

                            Mural Oncology

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                            AIChE Annual Meeting
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                            Mural Oncology

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                            AIChE Annual Meeting
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                            Lead Product(s) : Nemvaleukin Alfa

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Nemvaleukin Alfa Monotherapy and in Combination With Pembrolizumab in Patients With Advanced Cutaneous or Muco...

                            Details : Nemvaleukin Alfa is a Protein drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Melanoma, Cutaneous Malignant.

                            Product Name : Undisclosed

                            Product Type : Protein

                            Upfront Cash : Inapplicable

                            April 02, 2021

                            Lead Product(s) : Nemvaleukin Alfa

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            06

                            Mural Oncology

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                            AIChE Annual Meeting
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                            Mural Oncology

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                            Lead Product(s) : Nemvaleukin Alfa

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Less Frequent IV Dosing & Tumor Microenvironment (TME) Study of Nemvaleukin Alfa (ALKS 4230) Monotherapy and i...

                            Details : Nemvaleukin Alfa is a Protein drug candidate, which is currently being evaluated in phase I/ phase II clinical studies for the treatment of Neoplasms.

                            Product Name : Undisclosed

                            Product Type : Protein

                            Upfront Cash : Inapplicable

                            October 19, 2020

                            Lead Product(s) : Nemvaleukin Alfa

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            Mural Oncology

                            U.S.A arrow
                            AIChE Annual Meeting
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                            Mural Oncology

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                            AIChE Annual Meeting
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                            Lead Product(s) : Nemvaleukin Alfa

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Immune Oncology Network

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            A Study of ALKS 4230 (Nemvaleukin Alfa) With Pembrolizumab in Head and Neck Cancer

                            Details : Nemvaleukin Alfa is a Protein drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Squamous Cell Carcinoma of Head and Neck.

                            Product Name : Undisclosed

                            Product Type : Protein

                            Upfront Cash : Inapplicable

                            October 30, 2019

                            Lead Product(s) : Nemvaleukin Alfa

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Immune Oncology Network

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            08

                            Mural Oncology

                            U.S.A arrow
                            AIChE Annual Meeting
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                            Mural Oncology

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                            Lead Product(s) : ALKS 4230

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            A Dose Escalation and Cohort Expansion Study of Subcutaneously-Administered Cytokine ALKS 4230 (Nemvaleukin Al...

                            Details : ALKS4230 is a Protein drug candidate, which is currently being evaluated in phase I/ phase II clinical studies for the treatment of Neoplasms.

                            Product Name : Undisclosed

                            Product Type : Protein

                            Upfront Cash : Inapplicable

                            March 04, 2019

                            Lead Product(s) : ALKS 4230

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            09

                            Mural Oncology

                            U.S.A arrow
                            AIChE Annual Meeting
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                            Mural Oncology

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                            Lead Product(s) : ALKS 4230

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            A Study of the Effects of ALKS 4230 (Nemvaleukin Alfa) on Subjects With Solid Tumors

                            Details : ALKS4230 is a Protein drug candidate, which is currently being evaluated in phase I/ phase II clinical studies for the treatment of Neoplasms.

                            Product Name : Undisclosed

                            Product Type : Protein

                            Upfront Cash : Inapplicable

                            June 14, 2016

                            Lead Product(s) : ALKS 4230

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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