[{"orgOrder":0,"company":"Mosaic ImmunoEngineering","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Microorganism","year":"2021","type":"Inapplicable","leadProduct":"MIE-101","moa":"Toll-like receptor","graph1":"Oncology","graph2":"IND Enabling","graph3":"Mosaic ImmunoEngineering","amount2":0,"highestDevelopmentShortName":"IND","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intratumoral Injection","sponsorNew":"Mosaic ImmunoEngineering \/ Inapplicable","highestDevelopmentStatusID":"5","companyTruncated":"Mosaic ImmunoEngineering \/ Inapplicable"},{"orgOrder":0,"company":"Mosaic ImmunoEngineering","sponsor":"University of California San Diego","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Microorganism","year":"2021","type":"Licensing Agreement","leadProduct":"MIE-101","moa":"Toll-like receptor","graph1":"Oncology","graph2":"IND Enabling","graph3":"Mosaic ImmunoEngineering","amount2":0,"highestDevelopmentShortName":"IND","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intratumoral Injection","sponsorNew":"Mosaic ImmunoEngineering \/ University of California San Diego","highestDevelopmentStatusID":"5","companyTruncated":"Mosaic ImmunoEngineering \/ University of California San Diego"},{"orgOrder":0,"company":"Mosaic ImmunoEngineering","sponsor":"Oncotelic Therapeutics","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Oligonucleotide","year":"2024","type":"Acquisition","leadProduct":"Trabedersen","moa":"Transforming growth factor beta-2 mRNA","graph1":"Oncology","graph2":"Phase II","graph3":"Mosaic ImmunoEngineering","amount2":0.02,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0.02,"dosageForm":"Intravenous Infusion","sponsorNew":"Mosaic ImmunoEngineering \/ Mosaic ImmunoEngineering","highestDevelopmentStatusID":"8","companyTruncated":"Mosaic ImmunoEngineering \/ Mosaic ImmunoEngineering"}]

Find Clinical Drug Pipeline Developments & Deals by Mosaic ImmunoEngineering

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                          Therapeutic Area by Lead Product

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                          Top Deals by Deal Size (USD bn)

                          01

                          Pharmaconex
                          Not Confirmed
                          Pharmaconex
                          Not Confirmed

                          Details : Through the acquisition, the company will utilize OT-101 (trabedersen), currently under investigation in adult patients, for brain cancer and diffuse intrinsic pontine glioma.

                          Product Name : Undisclosed

                          Product Type : Oligonucleotide

                          Upfront Cash : Undisclosed

                          April 29, 2024

                          Lead Product(s) : Trabedersen

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Recipient : Oncotelic Therapeutics

                          Deal Size : $15.0 million

                          Deal Type : Acquisition

                          blank

                          02

                          Pharmaconex
                          Not Confirmed
                          Pharmaconex
                          Not Confirmed

                          Details : Under the agreement, Mosaic has licensed rights to develop and commercialize new treatment candidates including lead product, MIE-101, is derived from the cowpea mosaic virus (CPMV), that broaden the scope and capabilities of the protein nanoparticle pla...

                          Product Name : Undisclosed

                          Product Type : Microorganism

                          Upfront Cash : Undisclosed

                          June 10, 2021

                          Lead Product(s) : MIE-101

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : University of California San Diego

                          Deal Size : Undisclosed

                          Deal Type : Licensing Agreement

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                          03

                          Pharmaconex
                          Not Confirmed
                          Pharmaconex
                          Not Confirmed

                          Details : MIE-101, a Cowpea mosaic virus has shown to engage multiple Toll-like receptors on host immune cells in the tumor that have evolved to detect foreign invaders enhanced antitumor effects when combined with immune checkpoint inhibitors and other standard ...

                          Product Name : Undisclosed

                          Product Type : Microorganism

                          Upfront Cash : Inapplicable

                          January 11, 2021

                          Lead Product(s) : MIE-101

                          Therapeutic Area : Oncology

                          Highest Development Status : IND Enabling

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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