Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : MRT-8102
Therapeutic Area : Rheumatology
Study Phase : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Monte Rosa Starts Phase 1 for MRT-8102 Targeting Inflammatory Diseases
Details : MRT-8102, a NEK7-directed molecular glue degrader, which is being evaluated for the treatment of multiple inflammatory diseases.
Product Name : MRT-8102
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
July 21, 2025
Lead Product(s) : MRT-8102
Therapeutic Area : Rheumatology
Highest Development Status : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : MRT-2359
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Monte Rosa Updates MRT-2359 Phase 1/2 Study Progress for MYC-driven Tumors
Details : MRT-2359 is a potent, highly selective, and orally bioavailable investigational molecular glue degrader. Currently,It is being evaluated for the treatment of MYC-driven solid tumors.
Product Name : MRT-2359
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
December 05, 2024
Lead Product(s) : MRT-2359
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : MRT-6160
Therapeutic Area : Immunology
Study Phase : Phase I
Sponsor : Novartis Pharmaceuticals Corporation
Deal Size : $2,250.0 million
Deal Type : Licensing Agreement
Monte Rosa, Novartis Close Deal on VAV1 Molecular Glue for T And B Cell Modulation
Details : Under the licensing agreement, Novartis will gain exclusive global rights to develop, manufacture, and commercialize MRT-6160, currently under study for immune-mediated conditions.
Product Name : MRT-6160
Product Type : Other Small Molecule
Upfront Cash : $150.0 million
November 12, 2024
Lead Product(s) : MRT-6160
Therapeutic Area : Immunology
Highest Development Status : Phase I
Sponsor : Novartis Pharmaceuticals Corporation
Deal Size : $2,250.0 million
Deal Type : Licensing Agreement
Lead Product(s) : MRT-8102
Therapeutic Area : Rheumatology
Study Phase : IND Enabling
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Monte Rosa Begins IND Studies for MRT-8102, a NEK7 Directed Degrader
Details : MRT-8102 is a first-in-class NEK7-directed molecular glue degrader and NLRP3/IL-1β pathway inhibitor being evaluated for multiple inflammatory diseases, including gout and pericarditis.
Product Name : MRT-8102
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
November 03, 2024
Lead Product(s) : MRT-8102
Therapeutic Area : Rheumatology
Highest Development Status : IND Enabling
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : MRT-6160
Therapeutic Area : Immunology
Study Phase : Phase I
Sponsor : Novartis Pharmaceuticals Corporation
Deal Size : $2,250.0 million
Deal Type : Licensing Agreement
Monte Rosa Licenses VAV1 Molecular Glue Degraders to Novartis
Details : Under the licensing agreement, Novartis will gain exclusive global rights to develop, manufacture, and commercialize MRT-6160, currently under study for immune-mediated conditions.
Product Name : MRT-6160
Product Type : Other Small Molecule
Upfront Cash : $150.0 million
October 28, 2024
Lead Product(s) : MRT-6160
Therapeutic Area : Immunology
Highest Development Status : Phase I
Sponsor : Novartis Pharmaceuticals Corporation
Deal Size : $2,250.0 million
Deal Type : Licensing Agreement
Lead Product(s) : MRT-6160
Therapeutic Area : Immunology
Study Phase : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Monte Rosa Therapeutics Announces First Participants Dosed in MRT-6160 Phase 1 Study
Details : MRT-6160 is an orally bioavailable VAV1 degrader, which is being developed for the treatment of eurological autoimmune diseases.
Product Name : MRT-6160
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
August 19, 2024
Lead Product(s) : MRT-6160
Therapeutic Area : Immunology
Highest Development Status : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : MRT-2359
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Monte Rosa Therapeutics Provides Development Progress Updates on MRT-2359 and MRT-6160
Details : MRT-2359 is a potent, highly selective, and orally bioavailable investigational molecular glue degrader. Currently,It is being evaluated for the treatment of MYC-driven solid tumors.
Product Name : MRT-2359
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
June 27, 2024
Lead Product(s) : MRT-2359
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : MRT-6160
Therapeutic Area : Immunology
Study Phase : IND Enabling
Sponsor : TD Cowen
Deal Size : $100.0 million
Deal Type : Public Offering
Monte Rosa Therapeutics Announces Pricing of $100 Million Underwritten Public Offering
Details : The proceeds will fund the development of MRT-6160, an orally bioavailable VAV1 degrader, MRT-8102, as well the utilization of the QuEENTM platform to develop immunology and inflammation targets.
Product Name : MRT-6160
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
May 16, 2024
Lead Product(s) : MRT-6160
Therapeutic Area : Immunology
Highest Development Status : IND Enabling
Sponsor : TD Cowen
Deal Size : $100.0 million
Deal Type : Public Offering
Lead Product(s) : MRT-6160
Therapeutic Area : Immunology
Study Phase : IND Enabling
Sponsor : TD Cowen
Deal Size : Undisclosed
Deal Type : Public Offering
Monte Rosa Therapeutics Proposes Public Offering of Common Stock and Pre-Funded Warrants
Details : The proceeds will fund the development of MRT-6160, an orally bioavailable VAV1 degrader, MRT-8102, as well the utilization of the QuEENTM platform to develop immunology and inflammation targets.
Product Name : MRT-6160
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
May 15, 2024
Lead Product(s) : MRT-6160
Therapeutic Area : Immunology
Highest Development Status : IND Enabling
Sponsor : TD Cowen
Deal Size : Undisclosed
Deal Type : Public Offering
Lead Product(s) : MRT-2359
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : $25.0 million
Deal Type : Public Offering
Details : Monte Rosa intends to use the proceeds towards the advancement of its clinical and late preclinical pipeline, including MRT-2359, its orally bioavailable, GSPT1-directed MGD, MRT-6160, its orally bioavailable VAV1-directed MGD, and its NEK7 program.
Product Name : MRT-2359
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
October 26, 2023
Lead Product(s) : MRT-2359
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : $25.0 million
Deal Type : Public Offering