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    [{"orgOrder":0,"company":"Monte Rosa Therapeutics","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Miscellaneous","year":"2021","type":"Inapplicable","leadProduct":"MRT-048","moa":"GSPT1","graph1":"Oncology","graph2":"Preclinical","graph3":"Monte Rosa Therapeutics","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Monte Rosa Therapeutics \/ Undisclosed","highestDevelopmentStatusID":"4","companyTruncated":"Monte Rosa Therapeutics \/ Undisclosed"},{"orgOrder":0,"company":"Monte Rosa Therapeutics","sponsor":"Cancer Research Uk","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Miscellaneous","year":"2021","type":"Inapplicable","leadProduct":"MRT-048","moa":"GSPT1","graph1":"Oncology","graph2":"Preclinical","graph3":"Monte Rosa 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Hoffmann-La Roche"},{"orgOrder":0,"company":"Monte Rosa Therapeutics","sponsor":"Novartis Pharmaceuticals Corporation","pharmaFlowCategory":"D","therapeuticArea":"Immunology","country":"U.S.A","productType":"Miscellaneous","year":"2025","type":"Collaboration","leadProduct":"Undisclosed","moa":"Undisclosed","graph1":"Immunology","graph2":"Discovery Platform","graph3":"Monte Rosa Therapeutics","amount2":5.7000000000000002,"highestDevelopmentShortName":"Discovery Platform","therapeuticAreaShortName":"Immunology","amount2New":5.7000000000000002,"dosageForm":"Undisclosed","sponsorNew":"Monte Rosa Therapeutics \/ Novartis Pharmaceuticals Corporation","highestDevelopmentStatusID":"3","companyTruncated":"Monte Rosa Therapeutics \/ Novartis Pharmaceuticals Corporation"}]

    Find Clinical Drug Pipeline Developments & Deals by Monte Rosa Therapeutics

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                            01

                            Monte Rosa Therapeutics

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                            AIChE Annual Meeting
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                            Monte Rosa Therapeutics

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                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Immunology

                            Study Phase : Discovery Platform

                            Sponsor : Novartis Pharmaceuticals Corporation

                            Deal Size : $5,700.0 million

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            Monte Rosa Collaborates with Novartis for Degraders to Treat Immune-mediated Diseases

                            Details : Monte Rosa’s scientists will apply their proprietary AI/ML-enabled QuEEN product engine for the discovery and development of degraders to be further developed and commercialized by Novartis.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : $120.0 million

                            September 15, 2025

                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Immunology

                            Highest Development Status : Discovery Platform

                            Sponsor : Novartis Pharmaceuticals Corporation

                            Deal Size : $5,700.0 million

                            Deal Type : Collaboration

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                            02

                            Monte Rosa Therapeutics

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                            AIChE Annual Meeting
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                            Monte Rosa Therapeutics

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                            Lead Product(s) : MRT-8102

                            Therapeutic Area : Undisclosed

                            Study Phase : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            First-In-Human Study of MRT-8102 In Healthy and CV Risk Patients

                            Details : MRT-8102 is a Other Small Molecule drug candidate, which is currently being evaluated in Phase I clinical studies for the treatment of unspecified medical condition.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            August 12, 2025

                            Lead Product(s) : MRT-8102

                            Therapeutic Area : Undisclosed

                            Highest Development Status : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

                            Monte Rosa Therapeutics

                            U.S.A arrow
                            AIChE Annual Meeting
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                            Monte Rosa Therapeutics

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                            Lead Product(s) : MRT-6160

                            Therapeutic Area : Immunology

                            Study Phase : Phase I

                            Sponsor : Novartis Pharmaceuticals Corporation

                            Deal Size : $2,250.0 million

                            Deal Type : Licensing Agreement

                            DEALS_DEV arrow-down

                            Monte Rosa, Novartis Close Deal on VAV1 Molecular Glue for T And B Cell Modulation

                            Details : Under the licensing agreement, Novartis will gain exclusive global rights to develop, manufacture, and commercialize MRT-6160, currently under study for immune-mediated conditions.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : $150.0 million

                            December 11, 2024

                            Lead Product(s) : MRT-6160

                            Therapeutic Area : Immunology

                            Highest Development Status : Phase I

                            Sponsor : Novartis Pharmaceuticals Corporation

                            Deal Size : $2,250.0 million

                            Deal Type : Licensing Agreement

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                            04

                            Monte Rosa Therapeutics

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                            AIChE Annual Meeting
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                            Monte Rosa Therapeutics

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                            Lead Product(s) : MRT-2359

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Monte Rosa Updates MRT-2359 Phase 1/2 Study Progress for MYC-driven Tumors

                            Details : MRT-2359 is a potent, highly selective, and orally bioavailable investigational molecular glue degrader. Currently,It is being evaluated for the treatment of MYC-driven solid tumors.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            December 05, 2024

                            Lead Product(s) : MRT-2359

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            05

                            Monte Rosa Therapeutics

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                            AIChE Annual Meeting
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                            Monte Rosa Therapeutics

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                            Lead Product(s) : MRT-6160

                            Therapeutic Area : Immunology

                            Study Phase : Phase I

                            Sponsor : Novartis Pharmaceuticals Corporation

                            Deal Size : $2,250.0 million

                            Deal Type : Licensing Agreement

                            DEALS_DEV arrow-down

                            Monte Rosa Licenses VAV1 Molecular Glue Degraders to Novartis

                            Details : Under the licensing agreement, Novartis will gain exclusive global rights to develop, manufacture, and commercialize MRT-6160, currently under study for immune-mediated conditions.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : $150.0 million

                            October 28, 2024

                            Lead Product(s) : MRT-6160

                            Therapeutic Area : Immunology

                            Highest Development Status : Phase I

                            Sponsor : Novartis Pharmaceuticals Corporation

                            Deal Size : $2,250.0 million

                            Deal Type : Licensing Agreement

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                            06

                            Monte Rosa Therapeutics

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                            AIChE Annual Meeting
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                            Monte Rosa Therapeutics

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                            Lead Product(s) : MRT-6160

                            Therapeutic Area : Undisclosed

                            Study Phase : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            First-in-human Study of MRT-6160 in Healthy Subjects

                            Details : MRT-6160 is a Other Small Molecule drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of undefined medical condition.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            September 19, 2024

                            Lead Product(s) : MRT-6160

                            Therapeutic Area : Undisclosed

                            Highest Development Status : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            Monte Rosa Therapeutics

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                            AIChE Annual Meeting
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                            Monte Rosa Therapeutics

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                            Lead Product(s) : MRT-6160

                            Therapeutic Area : Immunology

                            Study Phase : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Monte Rosa Therapeutics Announces First Participants Dosed in MRT-6160 Phase 1 Study

                            Details : MRT-6160 is an orally bioavailable VAV1 degrader, which is being developed for the treatment of eurological autoimmune diseases.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            August 19, 2024

                            Lead Product(s) : MRT-6160

                            Therapeutic Area : Immunology

                            Highest Development Status : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            08

                            Monte Rosa Therapeutics

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                            AIChE Annual Meeting
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                            Monte Rosa Therapeutics

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                            Lead Product(s) : MRT-2359

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Monte Rosa Therapeutics Provides Development Progress Updates on MRT-2359 and MRT-6160

                            Details : MRT-2359 is a potent, highly selective, and orally bioavailable investigational molecular glue degrader. Currently,It is being evaluated for the treatment of MYC-driven solid tumors.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            June 27, 2024

                            Lead Product(s) : MRT-2359

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            09

                            Monte Rosa Therapeutics

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                            AIChE Annual Meeting
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                            Monte Rosa Therapeutics

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                            Lead Product(s) : MRT-6160

                            Therapeutic Area : Immunology

                            Study Phase : IND Enabling

                            Sponsor : TD Cowen

                            Deal Size : $100.0 million

                            Deal Type : Public Offering

                            DEALS_DEV arrow-down

                            Monte Rosa Therapeutics Announces Pricing of $100 Million Underwritten Public Offering

                            Details : The proceeds will fund the development of MRT-6160, an orally bioavailable VAV1 degrader, MRT-8102, as well the utilization of the QuEENTM platform to develop immunology and inflammation targets.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Undisclosed

                            May 16, 2024

                            Lead Product(s) : MRT-6160

                            Therapeutic Area : Immunology

                            Highest Development Status : IND Enabling

                            Sponsor : TD Cowen

                            Deal Size : $100.0 million

                            Deal Type : Public Offering

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                            Monte Rosa Therapeutics

                            U.S.A arrow
                            AIChE Annual Meeting
                            Not Confirmed

                            Monte Rosa Therapeutics

                            U.S.A arrow
                            AIChE Annual Meeting
                            Not Confirmed
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                            • WHO-GMP
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                            Lead Product(s) : MRT-6160

                            Therapeutic Area : Immunology

                            Study Phase : IND Enabling

                            Sponsor : TD Cowen

                            Deal Size : Undisclosed

                            Deal Type : Public Offering

                            DEALS_DEV arrow-down

                            Monte Rosa Therapeutics Proposes Public Offering of Common Stock and Pre-Funded Warrants

                            Details : The proceeds will fund the development of MRT-6160, an orally bioavailable VAV1 degrader, MRT-8102, as well the utilization of the QuEENTM platform to develop immunology and inflammation targets.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Undisclosed

                            May 15, 2024

                            Lead Product(s) : MRT-6160

                            Therapeutic Area : Immunology

                            Highest Development Status : IND Enabling

                            Sponsor : TD Cowen

                            Deal Size : Undisclosed

                            Deal Type : Public Offering

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