
Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target

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Lead Product(s) : Lorundrostat
Therapeutic Area : Cardiology/Vascular Diseases
Study Phase : Phase III
Sponsor : BofA Securities
Deal Size : $287.5 million
Deal Type : Public Offering
Mineralys Therapeutics Announces Closing of Upsized $287.5 Million
Details : Mineralys intends to use the net proceeds to fund clinical development of lorundrostat, a proprietary, orally administered, highly selective aldosterone synthase inhibitor.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Undisclosed
September 04, 2025
Lead Product(s) : Lorundrostat
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : Phase III
Sponsor : BofA Securities
Deal Size : $287.5 million
Deal Type : Public Offering

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Lead Product(s) : Lorundrostat
Therapeutic Area : Cardiology/Vascular Diseases
Study Phase : Phase III
Sponsor : BofA Securities
Deal Size : $250.0 million
Deal Type : Public Offering
Mineralys Therapeutics Announces Pricing of Upsized $250.0 Million
Details : Mineralys intends to use the net proceeds to fund clinical development of lorundrostat, a proprietary, orally administered, highly selective aldosterone synthase inhibitor.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Undisclosed
September 02, 2025
Lead Product(s) : Lorundrostat
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : Phase III
Sponsor : BofA Securities
Deal Size : $250.0 million
Deal Type : Public Offering

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Lead Product(s) : Lorundrostat
Therapeutic Area : Cardiology/Vascular Diseases
Study Phase : Phase III
Sponsor : BofA Securities
Deal Size : $175.0 million
Deal Type : Public Offering
Mineralys Therapeutics Announces Proposed Public Offering of Common Stock
Details : Mineralys intends to use the net proceeds to fund clinical development of lorundrostat, a proprietary, orally administered, highly selective aldosterone synthase inhibitor.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Undisclosed
September 02, 2025
Lead Product(s) : Lorundrostat
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : Phase III
Sponsor : BofA Securities
Deal Size : $175.0 million
Deal Type : Public Offering

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Lead Product(s) : Lorundrostat
Therapeutic Area : Cardiology/Vascular Diseases
Study Phase : Phase III
Sponsor : BofA Securities
Deal Size : $201.2 million
Deal Type : Public Offering
Mineralys Closes Underwriters' Option for Public Stock Offering
Details : The net proceeds from the offering will be used to fund the clinical development of MT-4129 (lorundrostat). It is being evaluated for the treatment of Uncontrolled or Resistant Hypertension.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Undisclosed
March 18, 2025
Lead Product(s) : Lorundrostat
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : Phase III
Sponsor : BofA Securities
Deal Size : $201.2 million
Deal Type : Public Offering

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Lead Product(s) : Lorundrostat
Therapeutic Area : Cardiology/Vascular Diseases
Study Phase : Phase III
Sponsor : BofA Securities
Deal Size : $175.0 million
Deal Type : Public Offering
Mineralys Prices $175M Underwritten Public Offering of Common Stock
Details : The net proceeds from the offering will be used to fund the clinical development of MT-4129 (lorundrostat). It is being evaluated for the treatment of Uncontrolled or Resistant Hypertension.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Undisclosed
March 11, 2025
Lead Product(s) : Lorundrostat
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : Phase III
Sponsor : BofA Securities
Deal Size : $175.0 million
Deal Type : Public Offering

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Lead Product(s) : Lorundrostat
Therapeutic Area : Cardiology/Vascular Diseases
Study Phase : Phase III
Sponsor : BofA Securities
Deal Size : $287.5 million
Deal Type : Public Offering
Mineralys Therapeutics Announces Proposed Public Offering of Common Stock
Details : The net proceeds from the offering will be used to fund the clinical development of MT-4129 (lorundrostat). It is being evaluated for the treatment of Uncontrolled or Resistant Hypertension.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Undisclosed
March 10, 2025
Lead Product(s) : Lorundrostat
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : Phase III
Sponsor : BofA Securities
Deal Size : $287.5 million
Deal Type : Public Offering

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Lead Product(s) : Lorundrostat
Therapeutic Area : Cardiology/Vascular Diseases
Study Phase : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Mineralys Reports Positive Lorundrostat Data in Uncontrolled Hypertension
Details : MLS-101 (lorundrostat) is a proprietary, orally administered, highly selective aldosterone synthase inhibitor being developed for the treatment of uncontrolled hypertension or resistant hypertension.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
March 10, 2025
Lead Product(s) : Lorundrostat
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Lorundrostat
Therapeutic Area : Nephrology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Mineralys Completes Enrollment in Explore-CKD Phase 2 Lorundrostat Trial
Details : MLS-101 (lorundrostat) is a proprietary, orally administered, highly selective aldosterone synthase inhibitor being developed for the treatment of uncontrolled hypertension or resistant hypertension.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
February 04, 2025
Lead Product(s) : Lorundrostat
Therapeutic Area : Nephrology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Lorundrostat
Therapeutic Area : Sleep
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Lorundrostat is a Other Small Molecule drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Sleep Apnea, Obstructive.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
January 21, 2025
Lead Product(s) : Lorundrostat
Therapeutic Area : Sleep
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Lorundrostat
Therapeutic Area : Cardiology/Vascular Diseases
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Mineralys Announces Phase 2 Trial of Lorundrostat for Sleep Apnea and Hypertension
Details : MLS-101 (lorundrostat) is an oral highly selective aldosterone synthase inhibitor. It is being evaluated for the treatment of obstructive sleep apnea in patients with hypertension.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
January 08, 2025
Lead Product(s) : Lorundrostat
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
