
Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target

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Lead Product(s) : TPST-1495
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Tempest Therapeutics
Deal Size : $30.0 million
Deal Type : Merger
Tempest and Millendo Announce Proposed Merger Agreement
Details : The merger will facilitate the advancement of our broad pipeline of targeted oncology programs, including TPST-1495 and TPST-1120, which are both progressing in the clinic with encouraging early signs of clinical benefit.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Undisclosed
March 29, 2021
Lead Product(s) : TPST-1495
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Tempest Therapeutics
Deal Size : $30.0 million
Deal Type : Merger

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Lead Product(s) : MLE-301
Therapeutic Area : Obstetrics/Gynecology (Women’s Health)
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Millendo Therapeutics Provides Pipeline and Business Update
Details : While MLE-301 was generally well-tolerated, the data do not support moving forward with its development in the target population of peri- and post-menopausal women, especially with the evolving dynamics of a highly competitive NK3R antagonist market.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Inapplicable
January 05, 2021
Lead Product(s) : MLE-301
Therapeutic Area : Obstetrics/Gynecology (Women’s Health)
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : MLE-301
Therapeutic Area : Obstetrics/Gynecology (Women’s Health)
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : The single ascending dose portion of the study will be conducted in healthy male volunteers, to determine the pharmacokinetics of MLE-301 and its pharmacodynamic profile as measured by reductions of biomarkers (luteinizing hormone, testosterone).
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Inapplicable
September 24, 2020
Lead Product(s) : MLE-301
Therapeutic Area : Obstetrics/Gynecology (Women’s Health)
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Livoletide
Therapeutic Area : Genetic Disease
Study Phase : Phase II/ Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Millendo Therapeutics Announces Topline Results for Pivotal Phase 2b Study of Livoletide
Details : Livoletide did not achieve statistically significant improvement in primary endpoint of change in hyperphagia and food-related behaviors relative to placebo.
Product Name : Undisclosed
Product Type : Peptide, Unconjugated
Upfront Cash : Inapplicable
April 06, 2020
Lead Product(s) : Livoletide
Therapeutic Area : Genetic Disease
Highest Development Status : Phase II/ Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Livoletide
Therapeutic Area : Genetic Disease
Study Phase : Phase II/ Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Effects of Livoletide (AZP-531) on Food-related Behaviors in Patients With Prader-Willi Syndrome
Details : Livoletide is a Peptide drug candidate, which is currently being evaluated in phase II/ phase III clinical studies for the treatment of Prader-Willi Syndrome.
Product Name : Undisclosed
Product Type : Peptide, Unconjugated
Upfront Cash : Inapplicable
January 02, 2019
Lead Product(s) : Livoletide
Therapeutic Area : Genetic Disease
Highest Development Status : Phase II/ Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Nevanimibe HCl
Therapeutic Area : Genetic Disease
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Nevanimibe HCl for the Treatment of Classic CAH
Details : Nevanimibe HCl is a drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Adrenal Hyperplasia, Congenital.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Inapplicable
September 13, 2018
Lead Product(s) : Nevanimibe HCl
Therapeutic Area : Genetic Disease
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Nevanimibe
Therapeutic Area : Endocrinology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
A Study of ATR-101 for the Treatment of Endogenous Cushing's Syndrome
Details : ATR-101 is a Other Small Molecule drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Cushing Syndrome.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
February 15, 2017
Lead Product(s) : Nevanimibe
Therapeutic Area : Endocrinology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : MLE4901
Therapeutic Area : Obstetrics/Gynecology (Women’s Health)
Study Phase : Phase II
Sponsor : Medpace, Inc | Covance
Deal Size : Inapplicable
Deal Type : Inapplicable
MLE4901 vs. Placebo for the Treatment of PCOS
Details : MLE4901 is a Other Small Molecule drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Polycystic Ovary Syndrome.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
August 15, 2016
Lead Product(s) : MLE4901
Therapeutic Area : Obstetrics/Gynecology (Women’s Health)
Highest Development Status : Phase II
Sponsor : Medpace, Inc | Covance
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Nevanimibe
Therapeutic Area : Genetic Disease
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
A Study of ATR-101 for the Treatment of Congenital Adrenal Hyperplasia
Details : ATR-101 is a Other Small Molecule drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Adrenal Hyperplasia, Congenital.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
June 17, 2016
Lead Product(s) : Nevanimibe
Therapeutic Area : Genetic Disease
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Nevanimibe
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Phase 1 Study of ATR-101 in Subjects With Advanced Adrenocortical Carcinoma
Details : ATR-101 is a Other Small Molecule drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Adrenocortical Carcinoma.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
July 12, 2013
Lead Product(s) : Nevanimibe
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
