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[{"orgOrder":0,"company":"Amicus Therapeutics","sponsor":"ARYA Sciences","pharmaFlowCategory":"D","amount":"$600.0 million","upfrontCash":"$50.0 million","newsHeadline":"Amicus Therapeutics and ARYA Sciences Acquisition Corp IV Announce Formation of a Next-Generation Genetic Medicine Company: \u201cCaritas Therapeutics\u201d","therapeuticArea":"Genetic Disease","highestDevelopmentStatus":"Approved","country":"U.S.A","productType":"Small molecule","productStatus":"Approved","date":"September 2021","url1":"","url2":"","graph1":"Genetic Disease","graph2":"Approved"},{"orgOrder":0,"company":"Amicus Therapeutics","sponsor":"Blackstone Life Sciences","pharmaFlowCategory":"D","amount":"$30.0 million","upfrontCash":"Undisclosed","newsHeadline":"Amicus Therapeutics and Blackstone Enter into $430 Million Strategic Financing Collaboration","therapeuticArea":"Genetic Disease","highestDevelopmentStatus":"Approved","country":"U.S.A","productType":"Small molecule","productStatus":"Approved","date":"October 2023","url1":"","url2":"","graph1":"Genetic Disease","graph2":"Approved"},{"orgOrder":0,"company":"Amicus Therapeutics","sponsor":"Not Applicable","pharmaFlowCategory":"DU","amount":"Not Applicable","upfrontCash":"Not Applicable","newsHeadline":"Amicus Announces Issuance of New U.S. Composition of Matter Patent for Galafold (migalastat), Strengthening Patent Protection Through 2038","therapeuticArea":"Genetic Disease","highestDevelopmentStatus":"Approved","country":"U.S.A","productType":"Small molecule","productStatus":"Approved","date":"April 2022","url1":"","url2":"","graph1":"Genetic Disease","graph2":"Approved"}]

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            Details:

            The proceeds will be used to fund the ongoing operations of the company, including Galafold (migalastat), a small molecule and the first and only oral therapy for adults with Fabry disease and an amenable GLA variant.

            Lead Product(s): Migalastat

            Therapeutic Area: Genetic Disease Product Name: Galafold

            Highest Development Status: Approved Product Type: Small molecule

            Partner/Sponsor/Collaborator: Blackstone Life Sciences

            Deal Size: $30.0 million Upfront Cash: Undisclosed

            Deal Type: Financing October 02, 2023

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            Details:

            New U.S. patent titled “Methods of Treating Fabry Patients Having Renal Impairments” is directed to a molecule comprising Galafold (migalastat) bound to an alpha-galactosidase A protein, it now includes 35 issued patents, 18 of which expire in 2038.

            Lead Product(s): Migalastat

            Therapeutic Area: Genetic Disease Product Name: Galafold

            Highest Development Status: Approved Product Type: Small molecule

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable April 19, 2022

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            Details:

            Amicus expects to use the net proceeds in the global commercialization of Galafold for Fabry disease through geographic and label expansion, as well as support for diagnostic initiatives and the anticipated global launch of AT-GAA.

            Lead Product(s): Migalastat

            Therapeutic Area: Genetic Disease Product Name: Galafold

            Highest Development Status: Approved Product Type: Small molecule

            Partner/Sponsor/Collaborator: ARYA Sciences

            Deal Size: $600.0 million Upfront Cash: $50.0 million

            Deal Type: Acquisition September 29, 2021

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