
Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target

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Lead Product(s) : MET-097
Therapeutic Area : Nutrition and Weight Loss
Study Phase : Phase II
Sponsor : Pfizer Inc
Deal Size : $4,900.0 million
Deal Type : Acquisition
Pfizer to Acquire Metsera and its Next-Generation Obesity Portfolio
Details : The acquisition brings a portfolio of differentiated oral and injectable incretin, non-incretin and combination therapies, including MET-097i, a weekly and monthly injectable GLP-1 receptor agonist.
Product Name : MET-097
Product Type : Peptide, Unconjugated
Upfront Cash : $4,900.0 million
September 22, 2025
Lead Product(s) : MET-097
Therapeutic Area : Nutrition and Weight Loss
Highest Development Status : Phase II
Sponsor : Pfizer Inc
Deal Size : $4,900.0 million
Deal Type : Acquisition

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Lead Product(s) : MET233
Therapeutic Area : Nutrition and Weight Loss
Study Phase : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
A Study of MET233 in Individuals with Obesity or Overweight
Details : MET233 is a drug candidate, which is currently being evaluated in Phase I/ Phase II clinical studies for the treatment of Obesity.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Inapplicable
June 15, 2025
Lead Product(s) : MET233
Therapeutic Area : Nutrition and Weight Loss
Highest Development Status : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : MET097
Therapeutic Area : Nutrition and Weight Loss
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : MET097 is a Other Small Molecule drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Obesity.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
May 15, 2025
Lead Product(s) : MET097
Therapeutic Area : Nutrition and Weight Loss
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : MET233
Therapeutic Area : Nutrition and Weight Loss
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : MET233 is a drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Obesity.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Inapplicable
April 11, 2025
Lead Product(s) : MET233
Therapeutic Area : Nutrition and Weight Loss
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : MET097
Therapeutic Area : Endocrinology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : MET097 is a Other Small Molecule drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Obesity-associated with Diabetes Mellitus.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
March 26, 2025
Lead Product(s) : MET097
Therapeutic Area : Endocrinology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : MET097
Therapeutic Area : Nutrition and Weight Loss
Study Phase : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : MET097 is a Other Small Molecule drug candidate, which is currently being evaluated in phase I/ phase II clinical studies for the treatment of Obesity.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
March 04, 2025
Lead Product(s) : MET097
Therapeutic Area : Nutrition and Weight Loss
Highest Development Status : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : MET097
Therapeutic Area : Nutrition and Weight Loss
Study Phase : Phase II
Sponsor : BofA Securities
Deal Size : $316.2 million
Deal Type : Public Offering
Metsera Closes IPO, Underwriters’ Option Fully Exercised
Details : The proceeds from the offering will used to fund the clinical development of MET097, which is being evalauted for the treatment of obesity.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Undisclosed
February 05, 2025
Lead Product(s) : MET097
Therapeutic Area : Nutrition and Weight Loss
Highest Development Status : Phase II
Sponsor : BofA Securities
Deal Size : $316.2 million
Deal Type : Public Offering

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Lead Product(s) : MET097
Therapeutic Area : Nutrition and Weight Loss
Study Phase : Phase II
Sponsor : BofA Securities
Deal Size : $275.0 million
Deal Type : Public Offering
Metsera Announces Pricing of Initial Public Offering
Details : The proceeds from the offering will used to fund the clinical development of MET097, which is being evalauted for the treatment of obesity.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Undisclosed
January 30, 2025
Lead Product(s) : MET097
Therapeutic Area : Nutrition and Weight Loss
Highest Development Status : Phase II
Sponsor : BofA Securities
Deal Size : $275.0 million
Deal Type : Public Offering

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Lead Product(s) : MET-097i
Therapeutic Area : Nutrition and Weight Loss
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Metsera Announces Positive Phase 2a Data for GLP-1 Agonist MET-097i
Details : MET-097i, its potential once-monthly, ultra-long acting, subcutaneously injectable, fully-biased, GLP-1 receptor agonist (RA), being investigated for obesity and overweight.
Product Name : Undisclosed
Product Type : Peptide, Unconjugated
Upfront Cash : Inapplicable
January 07, 2025
Lead Product(s) : MET-097i
Therapeutic Area : Nutrition and Weight Loss
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : MET097
Therapeutic Area : Nutrition and Weight Loss
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : MET097 is a Other Small Molecule drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Obesity.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
December 02, 2024
Lead Product(s) : MET097
Therapeutic Area : Nutrition and Weight Loss
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
