
Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target

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Lead Product(s) : Irinotecan Hydrochloride,Fluorouracil,Calcium Folinate
Therapeutic Area : Oncology
Study Phase : Approved FDF
Sponsor : Ipsen
Deal Size : $1,025.0 million
Deal Type : Acquisition
Merrimack Receives $225 Million Milestone Payment from Ipsen
Details : Ipsen acquired exclusive commercialization rights for Onivyde, an encapsulated formulation of irinotecan as a first-line treatment for metastatic adenocarcinoma of the pancreas in the US.
Product Name : Onivyde
Product Type : Miscellaneous
Upfront Cash : $575.0 million
March 27, 2024
Lead Product(s) : Irinotecan Hydrochloride,Fluorouracil,Calcium Folinate
Therapeutic Area : Oncology
Highest Development Status : Approved FDF
Sponsor : Ipsen
Deal Size : $1,025.0 million
Deal Type : Acquisition

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Lead Product(s) : Irinotecan Hydrochloride
Therapeutic Area : Oncology
Study Phase : Phase III
Recipient : Ipsen
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : The press release indicates that the “the primary endpoint OS was not met in patients treated with Onivyde (irinotecan) versus topotecan. However, a doubling of the secondary endpoint of objective response rate (ORR) in favor of Onivyde was observed.
Product Name : Onivyde
Product Type : Miscellaneous
Upfront Cash : Inapplicable
August 03, 2022
Lead Product(s) : Irinotecan Hydrochloride
Therapeutic Area : Oncology
Highest Development Status : Phase III
Recipient : Ipsen
Deal Size : Inapplicable
Deal Type : Inapplicable

A Study Evaluating MM-310 in Patients With Solid Tumors
Details : MM-310 is a drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Neoplasms.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Inapplicable
March 10, 2017

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Lead Product(s) : MM-151,Irinotecan Hydrochloride,Levoleucovorin Calcium,Calcium Folinate,Fluorouracil
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Evaluation of MM-151 + Nal-IRI + 5-FU + Leucovorin in RAS/RAF Wild-type Metastatic Colorectal Cancer
Details : MM-151 is a drug candidate, which is currently being evaluated in phase I/ phase II clinical studies for the treatment of Colorectal Neoplasms.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Inapplicable
May 27, 2016
Lead Product(s) : MM-151,Irinotecan Hydrochloride,Levoleucovorin Calcium,Calcium Folinate,Fluorouracil
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : MM-398,Irinotecan Hydrochloride,Calcium Folinate,Fluorouracil,Bevacizumab
Therapeutic Area : Oncology
Study Phase : Phase I
Recipient : GERCOR
Deal Size : Inapplicable
Deal Type : Inapplicable
A Dose Escalation Study of MM-398 Plus Irinotecan in Patients With Unresectable Advanced Cancer
Details : MM-398 is a Other Small Molecule drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Neoplasms.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
December 28, 2015
Lead Product(s) : MM-398,Irinotecan Hydrochloride,Calcium Folinate,Fluorouracil,Bevacizumab
Therapeutic Area : Oncology
Highest Development Status : Phase I
Recipient : GERCOR
Deal Size : Inapplicable
Deal Type : Inapplicable

Phase 1 Combination Study of MM-151 With MM-121, MM-141, or Trametinib
Details : MM-151 is a drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Colorectal Neoplasms.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Inapplicable
September 02, 2015

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Lead Product(s) : MM-141,Gemcitabine,Paclitaxel
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : MM-141 is a Antibody drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Pancreatic Neoplasms.
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Inapplicable
March 26, 2015
Lead Product(s) : MM-141,Gemcitabine,Paclitaxel
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : MM-121,Docetaxel
Therapeutic Area : Oncology
Study Phase : Phase II
Recipient : Elevation Oncology
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : MM-121 is a Antibody drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Carcinoma, Non-Small-Cell Lung.
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Inapplicable
March 12, 2015
Lead Product(s) : MM-121,Docetaxel
Therapeutic Area : Oncology
Highest Development Status : Phase II
Recipient : Elevation Oncology
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : MM-302,Trastuzumab
Therapeutic Area : Oncology
Study Phase : Phase II/ Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : MM-302 is a Antibody drug candidate, which is currently being evaluated in phase II/ phase III clinical studies for the treatment of Breast Neoplasms.
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Inapplicable
August 11, 2014
Lead Product(s) : MM-302,Trastuzumab
Therapeutic Area : Oncology
Highest Development Status : Phase II/ Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : MM-111,Paclitaxel,Trastuzumab
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : MM-111 is a Antibody drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Esophageal Neoplasms.
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Inapplicable
January 24, 2013
Lead Product(s) : MM-111,Paclitaxel,Trastuzumab
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
