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[{"orgOrder":0,"company":"Merrimack Pharmaceuticals","sponsor":"Ipsen","pharmaFlowCategory":"DU","amount":"Not Applicable","upfrontCash":"Not Applicable","newsHeadline":"Merrimack Provides Ipsen Report of Results From Phase III RESILIENT Trial Evaluating Onivyde\u00ae in Second-Line Monotherapy for Small Cell Lung Cancer","therapeuticArea":"Oncology","highestDevelopmentStatus":"Phase III","country":"U.S.A","productType":"Small molecule","productStatus":"Approved","date":"August 2022","url1":"","url2":"","graph1":"Oncology","graph2":"Phase III"},{"orgOrder":0,"company":"Merrimack Pharmaceuticals","sponsor":"Ipsen","pharmaFlowCategory":"D","amount":"$1,025.0 million","upfrontCash":"$575.0 million","newsHeadline":"Merrimack Receives $225 Million Milestone Payment from Ipsen","therapeuticArea":"Oncology","highestDevelopmentStatus":"Approved","country":"U.S.A","productType":"Small molecule","productStatus":"Approved","date":"March 2024","url1":"","url2":"","graph1":"Oncology","graph2":"Approved"}]

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            Details:

            Ipsen acquired exclusive commercialization rights for the current and potential future Onivyde, a unique encapsulation formulation of irinotecan in a long-circulating liposomal, as a first-line treatment of metastatic adenocarcinoma on the pancreas in the US.

            Lead Product(s): Irinotecan Hydrochloride,Fluorouracil,Calcium Folinate

            Therapeutic Area: Oncology Product Name: Onivyde

            Highest Development Status: Approved Product Type: Small molecule

            Partner/Sponsor/Collaborator: Ipsen

            Deal Size: $1,025.0 million Upfront Cash: $575.0 million

            Deal Type: Acquisition March 27, 2024

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            The press release indicates that the “the primary endpoint OS was not met in patients treated with Onivyde (irinotecan) versus topotecan. However, a doubling of the secondary endpoint of objective response rate (ORR) in favor of Onivyde was observed.

            Lead Product(s): Irinotecan Hydrochloride

            Therapeutic Area: Oncology Product Name: Onivyde

            Highest Development Status: Phase III Product Type: Small molecule

            Recipient: Ipsen

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable August 03, 2022

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