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    [{"orgOrder":0,"company":"Melior Pharmaceuticals","sponsor":"Adhera Therapeutics","pharmaFlowCategory":"D","therapeuticArea":"Neurology","country":"U.S.A","productType":"Other Small Molecule","year":"2021","type":"Licensing Agreement","leadProduct":"Armesocarb","moa":"||Dopamine reuptake","graph1":"Neurology","graph2":"Phase I","graph3":"Melior Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Oral","sponsorNew":"Melior Pharmaceuticals \/ Adhera Therapeutics","highestDevelopmentStatusID":"6","companyTruncated":"Melior Pharmaceuticals \/ Adhera Therapeutics"},{"orgOrder":0,"company":"Melior Pharmaceuticals","sponsor":"Adhera Therapeutics","pharmaFlowCategory":"D","therapeuticArea":"Neurology","country":"U.S.A","productType":"Other Small Molecule","year":"2021","type":"Acquisition","leadProduct":"Armesocarb","moa":"||Dopamine reuptake","graph1":"Neurology","graph2":"Phase I","graph3":"Melior Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Oral","sponsorNew":"Melior Pharmaceuticals \/ Adhera Therapeutics","highestDevelopmentStatusID":"6","companyTruncated":"Melior Pharmaceuticals \/ Adhera Therapeutics"},{"orgOrder":0,"company":"Melior Pharmaceuticals","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"U.S.A","productType":"Other Small Molecule","year":"2021","type":"Inapplicable","leadProduct":"Tolimidone","moa":"||Lyn kinase","graph1":"Infections and Infectious Diseases","graph2":"Preclinical","graph3":"Melior Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Oral","sponsorNew":"Melior Pharmaceuticals \/ Inapplicable","highestDevelopmentStatusID":"4","companyTruncated":"Melior Pharmaceuticals \/ Inapplicable"},{"orgOrder":0,"company":"Melior Pharmaceuticals","sponsor":"Adhera Therapeutics","pharmaFlowCategory":"D","therapeuticArea":"Endocrinology","country":"U.S.A","productType":"Other Small Molecule","year":"2021","type":"Licensing Agreement","leadProduct":"Tolimidone","moa":"||Lyn kinase","graph1":"Endocrinology","graph2":"Phase I","graph3":"Melior Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Endocrinology","amount2New":0,"dosageForm":"Oral Tablet","sponsorNew":"Melior Pharmaceuticals \/ Melior Pharmaceuticals","highestDevelopmentStatusID":"6","companyTruncated":"Melior Pharmaceuticals \/ Melior Pharmaceuticals"},{"orgOrder":0,"company":"Melior Pharmaceuticals","sponsor":"Commonwealth Of Pennsylvania\u2019S Covid-19 Vaccines","pharmaFlowCategory":"D","therapeuticArea":"Immunology","country":"U.S.A","productType":"Other Small Molecule","year":"2020","type":"Funding","leadProduct":"Tolimidone","moa":"||Lyn kinase","graph1":"Immunology","graph2":"Preclinical","graph3":"Melior Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Melior Pharmaceuticals \/ Commonwealth Of Pennsylvania\u2019S Covid-19 Vaccines","highestDevelopmentStatusID":"4","companyTruncated":"Melior Pharmaceuticals \/ Commonwealth Of Pennsylvania\u2019S Covid-19 Vaccines"}]

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                            01

                            Melior Pharmaceuticals

                            U.S.A arrow
                            EPSC
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                            Melior Pharmaceuticals

                            U.S.A arrow
                            EPSC
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                            Lead Product(s) : Tolimidone,Inapplicable

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Preclinical

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Melior Pharmaceuticals Receives IND Clearance from US FDA for COVID-19 Therapeutic

                            Details : The planned Phase 2 study is intended to recruit 236 subjects who were recently diagnosed with COVID-19, have early symptoms, but are not hospitalized. Tolimidone will be taken as an orally administered pill once a day.

                            Product Name : Undisclosed

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            September 03, 2021

                            Lead Product(s) : Tolimidone,Inapplicable

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Preclinical

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            02

                            Melior Pharmaceuticals

                            U.S.A arrow
                            EPSC
                            Not Confirmed

                            Melior Pharmaceuticals

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                            EPSC
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                            Lead Product(s) : Tolimidone,Inapplicable

                            Therapeutic Area : Endocrinology

                            Study Phase : Preclinical

                            Recipient : Adhera Therapeutics

                            Deal Size : Undisclosed

                            Deal Type : Licensing Agreement

                            DEALS_DEV arrow-down

                            Adhera Inks Exclusive License Agreement with Melior Pharmaceuticals for MLR-1023

                            Details : Adhera will license MLR-1023 (tolimidone) from Melior Pharma 1 for the purpose of developing a novel therapeutic for Type 1 diabetes. MLR-1023, a lyn kinase activator, which has shown exceptional clinical safety and tolerability in Phase 2a and Phase 2b ...

                            Product Name : Undisclosed

                            Product Type : Other Small Molecule

                            Upfront Cash : Undisclosed

                            August 24, 2021

                            Lead Product(s) : Tolimidone,Inapplicable

                            Therapeutic Area : Endocrinology

                            Highest Development Status : Preclinical

                            Recipient : Adhera Therapeutics

                            Deal Size : Undisclosed

                            Deal Type : Licensing Agreement

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                            03

                            Melior Pharmaceuticals

                            U.S.A arrow
                            EPSC
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                            Melior Pharmaceuticals

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                            EPSC
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                            Lead Product(s) : Armesocarb,Inapplicable

                            Therapeutic Area : Neurology

                            Study Phase : Phase I

                            Sponsor : Adhera Therapeutics

                            Deal Size : Undisclosed

                            Deal Type : Licensing Agreement

                            DEALS_DEV arrow-down

                            Melior Pharmaceuticals Announces Execution of License Agreement

                            Details : Melior has uncovered a previously unreported therapeutic potential of MLR-1019 in PD. As such it represents a new class of PD therapeutic which may be the only drug candidate to address both movement and non-movement aspects of PD.

                            Product Name : Undisclosed

                            Product Type : Other Small Molecule

                            Upfront Cash : Undisclosed

                            July 29, 2021

                            Lead Product(s) : Armesocarb,Inapplicable

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase I

                            Sponsor : Adhera Therapeutics

                            Deal Size : Undisclosed

                            Deal Type : Licensing Agreement

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                            04

                            Melior Pharmaceuticals

                            U.S.A arrow
                            EPSC
                            Not Confirmed

                            Melior Pharmaceuticals

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                            EPSC
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                            Lead Product(s) : Armesocarb,Inapplicable

                            Therapeutic Area : Neurology

                            Study Phase : Phase I

                            Sponsor : Adhera Therapeutics

                            Deal Size : Undisclosed

                            Deal Type : Acquisition

                            DEALS_DEV arrow-down

                            Melior Pharmaceuticals Announces Entry Into “Letter-of-Intent” for the Acquisition of Armesocarb by Adhera...

                            Details : Under the terms of the intended acquisition, Adhera will continue clinical development of MLR-1019 (Armesocarb ). Melior Pharmaceuticals will receive Adhera stock plus royalties.

                            Product Name : Undisclosed

                            Product Type : Other Small Molecule

                            Upfront Cash : Undisclosed

                            July 06, 2021

                            Lead Product(s) : Armesocarb,Inapplicable

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase I

                            Sponsor : Adhera Therapeutics

                            Deal Size : Undisclosed

                            Deal Type : Acquisition

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                            05

                            Melior Pharmaceuticals

                            U.S.A arrow
                            EPSC
                            Not Confirmed

                            Melior Pharmaceuticals

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                            EPSC
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                            Lead Product(s) : Tolimidone,Inapplicable

                            Therapeutic Area : Immunology

                            Study Phase : Preclinical

                            Sponsor : Commonwealth Of Pennsylvania’S Covid-19 Vaccines

                            Deal Size : Undisclosed

                            Deal Type : Funding

                            DEALS_DEV arrow-down

                            Melior Pharmaceuticals Awarded Grant for Advancing Pulmonary Therapeutic in COVID-19 Phase 2 Clinical Trial

                            Details : The Phase 2 clinical trial is intended to test tolimidone in subjects who were recently diagnosed with COVID19, but are not hospitalized. Tolimidone is expected to mitigate the probability and severity of COVID-19 subjects developing severe lung complica...

                            Product Name : Undisclosed

                            Product Type : Other Small Molecule

                            Upfront Cash : Undisclosed

                            September 15, 2020

                            Lead Product(s) : Tolimidone,Inapplicable

                            Therapeutic Area : Immunology

                            Highest Development Status : Preclinical

                            Sponsor : Commonwealth Of Pennsylvania’S Covid-19 Vaccines

                            Deal Size : Undisclosed

                            Deal Type : Funding

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                            06

                            Melior Pharmaceuticals

                            U.S.A arrow
                            EPSC
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                            Melior Pharmaceuticals

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                            EPSC
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                            Lead Product(s) : Tolimidone,Inapplicable

                            Therapeutic Area : Endocrinology

                            Study Phase : Phase II

                            Sponsor : Bukwang Pharmaceutical Co., Ltd

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            An Add-on Study of MLR-1023 in Adults With Uncontrolled Type 2 Diabetes on Metformin Therapy

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            September 12, 2017

                            Lead Product(s) : Tolimidone,Inapplicable

                            Therapeutic Area : Endocrinology

                            Highest Development Status : Phase II

                            Sponsor : Bukwang Pharmaceutical Co., Ltd

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            Melior Pharmaceuticals

                            U.S.A arrow
                            EPSC
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                            Melior Pharmaceuticals

                            U.S.A arrow
                            EPSC
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                            • EDQM
                            • WHO-GMP
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                            Lead Product(s) : Tolimidone,Inapplicable

                            Therapeutic Area : Endocrinology

                            Study Phase : Phase II

                            Sponsor : Bukwang Pharmaceutical Co., Ltd

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Adult Subjects With Uncontrolled Type 2 Diabetes

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            December 16, 2014

                            Lead Product(s) : Tolimidone,Inapplicable

                            Therapeutic Area : Endocrinology

                            Highest Development Status : Phase II

                            Sponsor : Bukwang Pharmaceutical Co., Ltd

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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