
Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target

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Lead Product(s) : MBX 4291
Therapeutic Area : Nutrition and Weight Loss
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
MBX 4291 Safety, Tolerability, PK/PD In Adults with Obesity
Details : MBX 4291 is a drug candidate, which is currently being evaluated in Phase I clinical studies for the treatment of Obesity.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Inapplicable
August 27, 2025
Lead Product(s) : MBX 4291
Therapeutic Area : Nutrition and Weight Loss
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : MBX 1416
Therapeutic Area : Endocrinology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Study of Subcutaneous MBX 1416 In Postbariatric Hypoglycemia Patients
Details : MBX 1416 is a Hormone drug candidate, which is currently being evaluated in Phase II clinical studies for the treatment of Post-Bariatric, Hypoglycemia.
Product Name : Undisclosed
Product Type : Hormone
Upfront Cash : Inapplicable
June 19, 2025
Lead Product(s) : MBX 1416
Therapeutic Area : Endocrinology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : MBX 4291
Therapeutic Area : Nutrition and Weight Loss
Study Phase : IND Enabling
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
MBX Biosciences Submits IND for MBX 4291 to Treat Obesity with GLP1/GIP Co-Agonist
Details : MBX 4291 is a long-acting GLP1/GIP Receptor co-agonist prodrug, which is currently being evaluated for the treatment of obesity.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Inapplicable
June 16, 2025
Lead Product(s) : MBX 4291
Therapeutic Area : Nutrition and Weight Loss
Highest Development Status : IND Enabling
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Canvuparatide
Therapeutic Area : Endocrinology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
MBX Biosciences Completes Enrollment in Phase 2 Avail Trial for MBX 2109
Details : MBX 2109 (canvuparatide) is a long-acting PTH peptide prodrug which is currently being evaluated for the treatment of patients with hypoparathyroidism.
Product Name : Undisclosed
Product Type : Peptide, Unconjugated
Upfront Cash : Inapplicable
March 03, 2025
Lead Product(s) : Canvuparatide
Therapeutic Area : Endocrinology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : MBX 1416
Therapeutic Area : Endocrinology
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
MBX Biosciences Announces Positive Phase 1 Results for MBX 1416 in Hypoglycemia
Details : MBX 1416 is a long-acting GLP-1 receptor antagonist, which is currently being evaluated for the treatment of post-bariatric hypoglycemia.
Product Name : Undisclosed
Product Type : Hormone
Upfront Cash : Inapplicable
January 07, 2025
Lead Product(s) : MBX 1416
Therapeutic Area : Endocrinology
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : MBX 1416
Therapeutic Area : Endocrinology
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
MBX Biosciences Completes Phase 1 MBX 1416 Study for Post-Bariatric Hypoglycemia
Details : MBX 1416 is a long-acting GLP-1 receptor antagonist, which is currently being evaluated for the treatment of post-bariatric hypoglycemia.
Product Name : Undisclosed
Product Type : Hormone
Upfront Cash : Inapplicable
November 18, 2024
Lead Product(s) : MBX 1416
Therapeutic Area : Endocrinology
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Canvuparatide
Therapeutic Area : Endocrinology
Study Phase : Phase II
Sponsor : J.P. Morgan
Deal Size : $187.7 million
Deal Type : Public Offering
MBX Biosciences Closes Upsized IPO, Underwriters Purchase Additional Shares
Details : The company will advance its clinical-stage programs including MBX 2109, a long-acting PTH peptide prodrug in development for the treatment of hypoparathyroidism.
Product Name : Undisclosed
Product Type : Peptide, Unconjugated
Upfront Cash : Undisclosed
September 16, 2024
Lead Product(s) : Canvuparatide
Therapeutic Area : Endocrinology
Highest Development Status : Phase II
Sponsor : J.P. Morgan
Deal Size : $187.7 million
Deal Type : Public Offering

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Lead Product(s) : Canvuparatide
Therapeutic Area : Endocrinology
Study Phase : Phase II
Sponsor : J.P. Morgan
Deal Size : $163.2 million
Deal Type : Public Offering
MBX Biosciences Announces Pricing of Initial Public Offering
Details : The proceeds will advance the development of MBX 2109 and MBX 1416, two clinical programs, MBX 4291. MBX 2109 is designed as a potential long-acting hormone replacement therapy for hypoparathyroidism.
Product Name : Undisclosed
Product Type : Peptide, Unconjugated
Upfront Cash : Undisclosed
September 12, 2024
Lead Product(s) : Canvuparatide
Therapeutic Area : Endocrinology
Highest Development Status : Phase II
Sponsor : J.P. Morgan
Deal Size : $163.2 million
Deal Type : Public Offering

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Lead Product(s) : Canvuparatide
Therapeutic Area : Endocrinology
Study Phase : Phase II
Sponsor : J.P. Morgan
Deal Size : $163.2 million
Deal Type : Public Offering
MBX Biosciences Announces Pricing of Initial Public Offering
Details : The company will advance its clinical-stage programs including MBX 2109, a long-acting PTH peptide prodrug in development for the treatment of hypoparathyroidism.
Product Name : Undisclosed
Product Type : Peptide, Unconjugated
Upfront Cash : Undisclosed
September 12, 2024
Lead Product(s) : Canvuparatide
Therapeutic Area : Endocrinology
Highest Development Status : Phase II
Sponsor : J.P. Morgan
Deal Size : $163.2 million
Deal Type : Public Offering

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Lead Product(s) : Canvuparatide
Therapeutic Area : Endocrinology
Study Phase : Phase II
Sponsor : J.P. Morgan
Deal Size : Undisclosed
Deal Type : Public Offering
MBX files for IPO, Seeking Cash to Take Challenger to Ascendis' Yorvipath into Phase 3
Details : The company will advance its clinical-stage programs including MBX 2109, a long-acting PTH peptide prodrug in development for the treatment of hypoparathyroidism.
Product Name : Undisclosed
Product Type : Peptide, Unconjugated
Upfront Cash : Undisclosed
August 26, 2024
Lead Product(s) : Canvuparatide
Therapeutic Area : Endocrinology
Highest Development Status : Phase II
Sponsor : J.P. Morgan
Deal Size : Undisclosed
Deal Type : Public Offering
