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Find Clinical Drug Pipeline Developments & Deals by Lumen Bioscience

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                          Top Deals by Deal Size (USD bn)

                          01

                          IMCAS Asia
                          Not Confirmed
                          IMCAS Asia
                          Not Confirmed

                          Details : LMN-201 is orally delivered (capsules) and highly scalable, allowing for much broader potential use in routine Clostridioides difficile infection management.

                          Product Name : LMN-201

                          Product Type : Protein

                          Upfront Cash : Inapplicable

                          April 03, 2025

                          Lead Product(s) : LMN-201

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase II/ Phase III

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          02

                          IMCAS Asia
                          Not Confirmed
                          IMCAS Asia
                          Not Confirmed

                          Details : The funds will develop and test a prototype broad-spectrum, fast-acting intranasal powder for treatment and prevention of viral respiratory infections. The therapeutic is a human immune signaling protein, important in the body's immune response to respir...

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : Undisclosed

                          November 05, 2023

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Preclinical

                          Sponsor : US Department of Defense

                          Deal Size : $8.8 million

                          Deal Type : Funding

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                          03

                          IMCAS Asia
                          Not Confirmed
                          IMCAS Asia
                          Not Confirmed

                          Details : The funding will be used to advance LMN-201, an investigational, orally delivered biologic drug to treat and prevent C. difficile infection, through late-stage trials.

                          Product Name : LMN-201

                          Product Type : Protein

                          Upfront Cash : Undisclosed

                          October 17, 2023

                          Lead Product(s) : LMN-201

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase II/ Phase III

                          Sponsor : US Department of Defense

                          Deal Size : $16.2 million

                          Deal Type : Funding

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                          04

                          IMCAS Asia
                          Not Confirmed
                          IMCAS Asia
                          Not Confirmed

                          Details : Due to synergy LMN-201 antibody cocktail, which targets C. difficile exotoxin B, is 300- to 3000-fold more potent at neutralizing most clinically prevalent TcdB toxin types than bezlotoxumab, only monoclonal antibody currently approved for treatment or p...

                          Product Name : LMN-201

                          Product Type : Protein

                          Upfront Cash : Inapplicable

                          April 18, 2022

                          Lead Product(s) : LMN-201

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase II/ Phase III

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          05

                          IMCAS Asia
                          Not Confirmed
                          IMCAS Asia
                          Not Confirmed

                          Details : LMN-101, a VHH-derived binding protein obtained from Spirulina designed to bind and inhibit FlaA, flagellin filament protein of Campylobacter jejuni to treat Campylobacter Infections.

                          Product Name : LMN-101

                          Product Type : Antibody

                          Upfront Cash : Inapplicable

                          March 21, 2022

                          Lead Product(s) : LMN-101

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          06

                          IMCAS Asia
                          Not Confirmed
                          IMCAS Asia
                          Not Confirmed

                          Details : The collaboration builds on previously published research pointing to a diversity of relevant biology within the gastrointestinal tract that can potentially be modulated with therapeutic proteins.

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : Undisclosed

                          June 16, 2021

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Nutrition and Weight Loss

                          Highest Development Status : Preclinical

                          Sponsor : Novo Nordisk

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

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                          07

                          IMCAS Asia
                          Not Confirmed
                          IMCAS Asia
                          Not Confirmed

                          Details : The support is provided by the US Army Medical Research and Development Command (USAMRDC) for preclinical development of LMN-301, an investigational product directed at treating and preventing the gastrointestinal (GI) manifestations of Covid-19.

                          Product Name : LMN-301

                          Product Type : Antibody

                          Upfront Cash : Undisclosed

                          June 10, 2021

                          Lead Product(s) : LMN-301

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : IND Enabling

                          Sponsor : USAMRDC

                          Deal Size : $4.0 million

                          Deal Type : Funding

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                          08

                          IMCAS Asia
                          Not Confirmed
                          IMCAS Asia
                          Not Confirmed

                          Details : The grant supports rapid development of an oral SARS-CoV-2 treatment and preventative product candidates through FDA Investigational New Drug (IND) submission and initial engineering work for a large-scale cGMP manufacturing plant.

                          Product Name : Undisclosed

                          Product Type : Antibody

                          Upfront Cash : Undisclosed

                          September 24, 2020

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Preclinical

                          Sponsor : USAMRDC

                          Deal Size : $4.0 million

                          Deal Type : Funding

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                          09

                          IMCAS Asia
                          Not Confirmed
                          IMCAS Asia
                          Not Confirmed

                          Details : The round brings Lumen’s total equity and non-dilutive investment to $68 million and will support continued advancement of Lumen’s three clinical programs for C. difficile, norovirus and traveler’s diarrhea.

                          Product Name : LMN-101

                          Product Type : Antibody

                          Upfront Cash : Undisclosed

                          January 09, 2020

                          Lead Product(s) : LMN-101

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase I

                          Sponsor : Westriver Management

                          Deal Size : $16.0 million

                          Deal Type : Series B Financing

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