Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : LMN-201
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase II/ Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lumen’s LMN-201 Hits 100% Cure Rate in Early C. difficile Trial
Details : LMN-201 is orally delivered (capsules) and highly scalable, allowing for much broader potential use in routine Clostridioides difficile infection management.
Product Name : LMN-201
Product Type : Protein
Upfront Cash : Inapplicable
April 03, 2025
Lead Product(s) : LMN-201
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase II/ Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Undisclosed
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Preclinical
Sponsor : US Department of Defense
Deal Size : $8.8 million
Deal Type : Funding
Details : The funds will develop and test a prototype broad-spectrum, fast-acting intranasal powder for treatment and prevention of viral respiratory infections. The therapeutic is a human immune signaling protein, important in the body's immune response to respir...
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Undisclosed
November 05, 2023
Lead Product(s) : Undisclosed
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Preclinical
Sponsor : US Department of Defense
Deal Size : $8.8 million
Deal Type : Funding
Lead Product(s) : LMN-201
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase II/ Phase III
Sponsor : US Department of Defense
Deal Size : $16.2 million
Deal Type : Funding
Lumen Bioscience Awarded $16.2 Million in DoD Funding to Advance LMN-201 through Late-Stage Trials
Details : The funding will be used to advance LMN-201, an investigational, orally delivered biologic drug to treat and prevent C. difficile infection, through late-stage trials.
Product Name : LMN-201
Product Type : Protein
Upfront Cash : Undisclosed
October 17, 2023
Lead Product(s) : LMN-201
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase II/ Phase III
Sponsor : US Department of Defense
Deal Size : $16.2 million
Deal Type : Funding
Lead Product(s) : LMN-201
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase II/ Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lumen Bioscience Announces Clinical Advancement of LMN-201 for C. difficile Infection
Details : Due to synergy LMN-201 antibody cocktail, which targets C. difficile exotoxin B, is 300- to 3000-fold more potent at neutralizing most clinically prevalent TcdB toxin types than bezlotoxumab, only monoclonal antibody currently approved for treatment or p...
Product Name : LMN-201
Product Type : Protein
Upfront Cash : Inapplicable
April 18, 2022
Lead Product(s) : LMN-201
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase II/ Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : LMN-101
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : LMN-101, a VHH-derived binding protein obtained from Spirulina designed to bind and inhibit FlaA, flagellin filament protein of Campylobacter jejuni to treat Campylobacter Infections.
Product Name : LMN-101
Product Type : Antibody
Upfront Cash : Inapplicable
March 21, 2022
Lead Product(s) : LMN-101
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Undisclosed
Therapeutic Area : Nutrition and Weight Loss
Study Phase : Preclinical
Sponsor : Novo Nordisk
Deal Size : Undisclosed
Deal Type : Collaboration
Details : The collaboration builds on previously published research pointing to a diversity of relevant biology within the gastrointestinal tract that can potentially be modulated with therapeutic proteins.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Undisclosed
June 16, 2021
Lead Product(s) : Undisclosed
Therapeutic Area : Nutrition and Weight Loss
Highest Development Status : Preclinical
Sponsor : Novo Nordisk
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : LMN-301
Therapeutic Area : Infections and Infectious Diseases
Study Phase : IND Enabling
Sponsor : USAMRDC
Deal Size : $4.0 million
Deal Type : Funding
Details : The support is provided by the US Army Medical Research and Development Command (USAMRDC) for preclinical development of LMN-301, an investigational product directed at treating and preventing the gastrointestinal (GI) manifestations of Covid-19.
Product Name : LMN-301
Product Type : Antibody
Upfront Cash : Undisclosed
June 10, 2021
Lead Product(s) : LMN-301
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : IND Enabling
Sponsor : USAMRDC
Deal Size : $4.0 million
Deal Type : Funding
Lead Product(s) : Undisclosed
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Preclinical
Sponsor : USAMRDC
Deal Size : $4.0 million
Deal Type : Funding
Lumen Bioscience Awarded Federal Grant to Rapidly Develop Nanobody-based Covid-19 Therapeutic
Details : The grant supports rapid development of an oral SARS-CoV-2 treatment and preventative product candidates through FDA Investigational New Drug (IND) submission and initial engineering work for a large-scale cGMP manufacturing plant.
Product Name : Undisclosed
Product Type : Antibody
Upfront Cash : Undisclosed
September 24, 2020
Lead Product(s) : Undisclosed
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Preclinical
Sponsor : USAMRDC
Deal Size : $4.0 million
Deal Type : Funding
Lead Product(s) : LMN-101
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase I
Sponsor : Westriver Management
Deal Size : $16.0 million
Deal Type : Series B Financing
Details : The round brings Lumen’s total equity and non-dilutive investment to $68 million and will support continued advancement of Lumen’s three clinical programs for C. difficile, norovirus and traveler’s diarrhea.
Product Name : LMN-101
Product Type : Antibody
Upfront Cash : Undisclosed
January 09, 2020
Lead Product(s) : LMN-101
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase I
Sponsor : Westriver Management
Deal Size : $16.0 million
Deal Type : Series B Financing