
 
													
 
									 
															 
															Year
 
															DEALS // DEV.
 
															Country
 
															 
															Therapeutic Area
 
															Study Phase
 
															Deal Type
 
															Product Type
 
															Dosage Form
 
															Lead Product
 
															Target

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Lead Product(s) : Fosdenopterin,Lonafarnib
Therapeutic Area : Genetic Disease
Study Phase : Approved FDF
Sponsor : Sentynl Therapeutics
Deal Size : Undisclosed
Deal Type : Agreement
Er-Kim, Sentynl Therapeutics Partner on Nulibry® and Zokinvy® for Ultra-Rare Diseases
Details : The agreement aims to Commercialization of Nulibry (fosdenopterin), targeting phosphoro-derivatives for Molybdenum cofactor deficiency Type A.
Product Name : Nulibry
Product Type : Miscellaneous
Upfront Cash : Undisclosed
September 24, 2025
Lead Product(s) : Fosdenopterin,Lonafarnib
Therapeutic Area : Genetic Disease
Highest Development Status : Approved FDF
Sponsor : Sentynl Therapeutics
Deal Size : Undisclosed
Deal Type : Agreement

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Lead Product(s) : Lonafarnib
Therapeutic Area : Genetic Disease
Study Phase : Approved FDF
Sponsor : Sentynl Therapeutics
Deal Size : Undisclosed
Deal Type : Acquisition
Sentynl Acquires Zokinvy® for Hutchinson-Gilford Progeria Syndrome
Details : Sentynl will commercialize Zokinvy (lonafarnib) globally, the first FDA-approved treatment targeting progeria symptoms.
Product Name : Zokinvy
Product Type : Miscellaneous
Upfront Cash : Undisclosed
May 03, 2024
Lead Product(s) : Lonafarnib
Therapeutic Area : Genetic Disease
Highest Development Status : Approved FDF
Sponsor : Sentynl Therapeutics
Deal Size : Undisclosed
Deal Type : Acquisition

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Lead Product(s) : Lonafarnib
Therapeutic Area : Genetic Disease
Study Phase : Approved FDF
Sponsor : AnGes
Deal Size : Inapplicable
Deal Type : Inapplicable
Eiger and AnGes Receive Approval for Zokinvy® for Hutchinson-Gilford Progeria in Japan
Details : Zokinvy (lonafarnib) is a first-in-class farnesyltransferase inhibitor. It is approved for Hutchinson- Gilford Progeria Syndrome and Processing-Deficient Progeroid Laminopathies.
Product Name : Zokinvy
Product Type : Miscellaneous
Upfront Cash : Inapplicable
January 18, 2024
Lead Product(s) : Lonafarnib
Therapeutic Area : Genetic Disease
Highest Development Status : Approved FDF
Sponsor : AnGes
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Lonafarnib
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Lonafarnib is a first-in-class, oral prenylation inhibitor which inhibits a host enzyme, blocking a critical step in HDV viral assembly. Lonafarnib has been dosed in over 450 chronically infected HDV patients across global clinical sites, including the P...
Product Name : Zokinvy
Product Type : Miscellaneous
Upfront Cash : Inapplicable
December 08, 2022
Lead Product(s) : Lonafarnib
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Lonafarnib
Therapeutic Area : Genetic Disease
Study Phase : Approved FDF
Sponsor : The Progeria Research Foundation
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Zokinvy® (lonafarnib), is a first-in-class disease-modifying agent that blocks the accumulation of defective progerin and progerin-like proteins which leads to cellular instability and premature aging in children and young adults with progeria.
Product Name : Zokinvy
Product Type : Miscellaneous
Upfront Cash : Inapplicable
July 20, 2022
Lead Product(s) : Lonafarnib
Therapeutic Area : Genetic Disease
Highest Development Status : Approved FDF
Sponsor : The Progeria Research Foundation
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Lonafarnib,Peginterferon Lambda,Ritonavir
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Sarasar (lonafarnib) is a well-characterized, first-in-class, inhibitor of farnesyl-transferase, an enzyme involved in modification of proteins through a process called prenylation. HDV uses this host cell process inside liver cells to complete a key ste...
Product Name : Zokinvy
Product Type : Miscellaneous
Upfront Cash : Inapplicable
June 24, 2022
Lead Product(s) : Lonafarnib,Peginterferon Lambda,Ritonavir
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Lonafarnib,Peginterferon Lambda,Ritonavir
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Zokinvy (lonafarnib), is a well-characterized, first-in-class, orally active inhibitor of farnesyl transferase, an enzyme involved in modification of proteins through a process called prenylation.
Product Name : Zokinvy
Product Type : Miscellaneous
Upfront Cash : Inapplicable
June 08, 2022
Lead Product(s) : Lonafarnib,Peginterferon Lambda,Ritonavir
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Lonafarnib
Therapeutic Area : Genetic Disease
Study Phase : Approved FDF
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Zokinvy (lonafarnib) is a first-in-class disease-modifying agent that has demonstrated a statistically significant survival benefit in children and young adults with HGPS.
Product Name : Zokinvy
Product Type : Miscellaneous
Upfront Cash : Inapplicable
May 20, 2022
Lead Product(s) : Lonafarnib
Therapeutic Area : Genetic Disease
Highest Development Status : Approved FDF
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Lonafarnib
Therapeutic Area : Genetic Disease
Study Phase : Approved FDF
Sponsor : AnGes
Deal Size : Undisclosed
Deal Type : Partnership
Details : Under the terms of the agreement, AnGes is responsible for obtaining and maintaining regulatory approval for Zokinvy (lonafarnib) in Japan and will be the exclusive partner for distribution and commercialization.
Product Name : Zokinvy
Product Type : Miscellaneous
Upfront Cash : Undisclosed
May 10, 2022
Lead Product(s) : Lonafarnib
Therapeutic Area : Genetic Disease
Highest Development Status : Approved FDF
Sponsor : AnGes
Deal Size : Undisclosed
Deal Type : Partnership

Lead Product(s) : Lonafarnib
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase III
Sponsor : Eiger BioPharmaceuticals
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Lonafarnib is a Other Small Molecule drug candidate, which is currently being evaluated in phase III clinical studies for the treatment of Hepatitis D, Chronic.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
February 08, 2022
Lead Product(s) : Lonafarnib
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase III
Sponsor : Eiger BioPharmaceuticals
Deal Size : Inapplicable
Deal Type : Inapplicable

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