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Gold | Prof. Dr. Soyoung Q Park | Ulrike Grittner | Motognosis GmbH"},{"orgOrder":0,"company":"PureIMS","sponsor":"Cooperative Clinical Drug Research and Development AG","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"NETHERLANDS","productType":"Miscellaneous","year":"2023","type":"Inapplicable","leadProduct":"Levodopa","moa":"Dopamine D3 receptor","graph1":"Neurology","graph2":"Phase I","graph3":"PureIMS","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"PureIMS \/ Cooperative Clinical Drug Research and Development AG","highestDevelopmentStatusID":"6","companyTruncated":"PureIMS \/ Cooperative Clinical Drug Research and Development AG"},{"orgOrder":0,"company":"Neuraxpharm","sponsor":"Dizlin Pharmaceuticals","pharmaFlowCategory":"D","therapeuticArea":"Neurology","country":"SPAIN","productType":"Miscellaneous","year":"2025","type":"Agreement","leadProduct":"Levodopa","moa":"||Dopamine D3 receptor","graph1":"Neurology","graph2":"Phase I","graph3":"Neuraxpharm","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Infusion","sponsorNew":"Neuraxpharm \/ Dizlin Pharmaceuticals","highestDevelopmentStatusID":"6","companyTruncated":"Neuraxpharm \/ Dizlin Pharmaceuticals"},{"orgOrder":0,"company":"University of British Columbia","sponsor":"Providence Health & Services","pharmaFlowCategory":"DU","therapeuticArea":"Psychiatry\/Psychology","country":"CANADA","productType":"Miscellaneous","year":"2024","type":"Inapplicable","leadProduct":"Levodopa","moa":"Dopamine D3 receptor","graph1":"Psychiatry\/Psychology","graph2":"Phase II","graph3":"University of British Columbia","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Psychiatry","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"University of British Columbia \/ Providence Health & Services","highestDevelopmentStatusID":"8","companyTruncated":"University of British Columbia \/ Providence Health & Services"},{"orgOrder":0,"company":"Synagile","sponsor":"Clintrex Research | TFS Trial Form Support | Clinical Data Science","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"U.S.A","productType":"Miscellaneous","year":"2021","type":"Inapplicable","leadProduct":"Levodopa","moa":"Dopamine D3 receptor","graph1":"Neurology","graph2":"Phase II","graph3":"Synagile","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Synagile \/ Clintrex Research | TFS Trial Form Support | Clinical Data Science","highestDevelopmentStatusID":"8","companyTruncated":"Synagile \/ Clintrex Research | TFS Trial Form Support | Clinical Data Science"},{"orgOrder":0,"company":"Andromaco","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Undisclosed","country":"CHILE","productType":"Miscellaneous","year":"2022","type":"Inapplicable","leadProduct":"Levodopa","moa":"Dopamine D3 receptor","graph1":"Undisclosed","graph2":"Phase I","graph3":"Andromaco","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Andromaco \/ Undisclosed","highestDevelopmentStatusID":"6","companyTruncated":"Andromaco \/ Undisclosed"}]

Find Clinical Drug Pipeline Developments & Deals for Levodopa

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                          Top Deals by Deal Size (USD bn)

                          01

                          FNCE
                          Not Confirmed
                          FNCE
                          Not Confirmed

                          Details : Infudopa SubC is a ready-to-use levodopa-carbidopa solution delivered via a wearable subcutaneous infusion belt pump.

                          Product Name : Infudopa SubC

                          Product Type : Miscellaneous

                          Upfront Cash : Undisclosed

                          July 08, 2025

                          Lead Product(s) : Levodopa,Carbidopa

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase I

                          Sponsor : Dizlin Pharmaceuticals

                          Deal Size : Undisclosed

                          Deal Type : Agreement

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                          02

                          FNCE
                          Not Confirmed
                          FNCE
                          Not Confirmed

                          Details : Crexont is a combination of carbidopa and levodopa indicated for the treatment of Parkinson’s disease, post-encephalitic parkinsonism, and parkinsonism.

                          Product Name : Crexont

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          April 07, 2025

                          Lead Product(s) : Carbidopa,Levodopa

                          Therapeutic Area : Neurology

                          Highest Development Status : Approved FDF

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          03

                          FNCE
                          Not Confirmed
                          FNCE
                          Not Confirmed

                          Details : A new generation levodopa/carbidopa asset LXM.5 is being developed for the treatment of patients with parkinson's disease (PD).

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          February 04, 2025

                          Lead Product(s) : Levodopa,Carbidopa

                          Therapeutic Area : Neurology

                          Highest Development Status : Preclinical

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          04

                          University of British Columbia

                          Country arrow
                          FNCE
                          Not Confirmed

                          University of British Columbia

                          Country arrow
                          FNCE
                          Not Confirmed

                          Details : Levodopa is a Other Small Molecule drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Depressive Disorder, Major.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          October 03, 2024

                          Lead Product(s) : Levodopa

                          Therapeutic Area : Psychiatry/Psychology

                          Highest Development Status : Phase II

                          Sponsor : Providence Health & Services

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          05

                          FNCE
                          Not Confirmed
                          FNCE
                          Not Confirmed

                          Details : ND0612 is a continuous, subcutaneous infusion levodopa/carbidopa delivery system under development for patients with Parkinson's disease (PD) and motor fluctuations.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          September 30, 2024

                          Lead Product(s) : Levodopa,Carbidopa

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase III

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          06

                          FNCE
                          Not Confirmed
                          FNCE
                          Not Confirmed

                          Details : Crexont is a novel, oral carbidopa/levodopa (CD/LD) formulation that combines immediate-release granules and extended-release pellets. It indicated for the treatment of Parkinson’s disease

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          September 23, 2024

                          Lead Product(s) : Carbidopa,Levodopa

                          Therapeutic Area : Neurology

                          Highest Development Status : Approved FDF

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          07

                          FNCE
                          Not Confirmed
                          FNCE
                          Not Confirmed

                          Details : Crexont (carbidopa/levodopa) is a novel, oral extended-release capsule formulation. It is indicated for the treatment of parkinson's disease with motor fluctuations.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          August 07, 2024

                          Lead Product(s) : Carbidopa,Levodopa

                          Therapeutic Area : Neurology

                          Highest Development Status : Approved FDF

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          08

                          FNCE
                          Not Confirmed
                          FNCE
                          Not Confirmed

                          Details : Merz purchases substantially all of the assets of Acorda, including the rights to Inbrija (levodopa inhalation powder), which is used when needed for OFF episodes in adults with Parkinson's disease.

                          Product Name : Inbrija

                          Product Type : Miscellaneous

                          Upfront Cash : Undisclosed

                          July 10, 2024

                          Lead Product(s) : Levodopa

                          Therapeutic Area : Neurology

                          Highest Development Status : Approved FDF

                          Sponsor : Merz Pharma

                          Deal Size : $185.0 million

                          Deal Type : Acquisition

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                          09

                          FNCE
                          Not Confirmed
                          FNCE
                          Not Confirmed

                          Details : Merz Therapeutics will acquire Acorda's assets, including Inbrija (levodopa inhalation) for OFF episodes in Parkinson’s and Ampyra (dalfampridine).

                          Product Name : Inbrija

                          Product Type : Miscellaneous

                          Upfront Cash : Undisclosed

                          April 02, 2024

                          Lead Product(s) : Levodopa

                          Therapeutic Area : Neurology

                          Highest Development Status : Approved FDF

                          Sponsor : Merz Pharma

                          Deal Size : $185.0 million

                          Deal Type : Acquisition

                          blank

                          10

                          FNCE
                          Not Confirmed
                          FNCE
                          Not Confirmed

                          Details : Through the licensing agreement, Zambon will commercialize IPX203, an oral formulation of carbidopa/levodopa extended-release capsules designed for the treatment of Parkinson’s disease.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Undisclosed

                          February 27, 2024

                          Lead Product(s) : Carbidopa,Levodopa

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase III

                          Sponsor : Zambon Group SpA

                          Deal Size : Undisclosed

                          Deal Type : Licensing Agreement

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