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therapy","year":"2025","type":"Inapplicable","leadProduct":"LCAR-AIO T Cell","moa":"Undisclosed","graph1":"Neurology","graph2":"Phase I","graph3":"Legend Biotech","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Infusion","sponsorNew":"Legend Biotech \/ Legend Biotech","highestDevelopmentStatusID":"6","companyTruncated":"Legend Biotech \/ Legend Biotech"},{"orgOrder":0,"company":"Legend Biotech","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Cell and Gene therapy","year":"2022","type":"Inapplicable","leadProduct":"LB2102","moa":"DLL3","graph1":"Oncology","graph2":"Phase I","graph3":"Legend Biotech","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Infusion","sponsorNew":"Legend Biotech \/ Inapplicable","highestDevelopmentStatusID":"6","companyTruncated":"Legend Biotech \/ Inapplicable"}]

Find Clinical Drug Pipeline Developments & Deals by Legend Biotech

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                          Therapeutic Area by Lead Product

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                          Top Deals by Deal Size (USD bn)

                          01

                          ChemOutsourcing
                          Not Confirmed
                          ChemOutsourcing
                          Not Confirmed

                          Details : Undisclosed

                          Product Name : Undisclosed

                          Product Type : Cell and Gene therapy

                          Upfront Cash : Inapplicable

                          March 11, 2025

                          Lead Product(s) : LCAR-AIO T Cell

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase I

                          Recipient : Wuhan Union Hospital

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          02

                          ChemOutsourcing
                          Not Confirmed
                          ChemOutsourcing
                          Not Confirmed

                          Details : Undisclosed

                          Product Name : Undisclosed

                          Product Type : Cell and Gene therapy

                          Upfront Cash : Inapplicable

                          March 10, 2025

                          Lead Product(s) : LCAR-AIO T Cell

                          Therapeutic Area : Immunology

                          Highest Development Status : Phase I

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          03

                          ChemOutsourcing
                          Not Confirmed
                          ChemOutsourcing
                          Not Confirmed

                          Details : Carvykti (ciltacabtagene autoleucel) is an FDA-approved genetically modified autologous T cell immunotherapy that inhibits BCMA. It is administered intravenously for the treatment of r/r MM in adults.

                          Product Name : Carvykti

                          Product Type : Cell and Gene therapy

                          Upfront Cash : Inapplicable

                          December 09, 2024

                          Lead Product(s) : Ciltacabtagene Autoleucel

                          Therapeutic Area : Oncology

                          Highest Development Status : Approved FDF

                          Sponsor : Johnson & Johnson Innovative Medicine

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          04

                          ChemOutsourcing
                          Not Confirmed
                          ChemOutsourcing
                          Not Confirmed

                          Details : Carvykti (ciltacabtagene autoleucel) is a FDA approved BCMA-directed genetically modified autologous T cell immunotherapy indicated for the treatment of relapsed/refractory multiple myeloma in adults.

                          Product Name : Carvykti

                          Product Type : Cell and Gene therapy

                          Upfront Cash : Inapplicable

                          August 27, 2024

                          Lead Product(s) : Ciltacabtagene Autoleucel

                          Therapeutic Area : Oncology

                          Highest Development Status : Approved FDF

                          Sponsor : GenScript Biotech Corporation

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          05

                          ChemOutsourcing
                          Not Confirmed
                          ChemOutsourcing
                          Not Confirmed

                          Details : Undisclosed

                          Product Name : Undisclosed

                          Product Type : Cell and Gene therapy

                          Upfront Cash : Inapplicable

                          July 10, 2024

                          Lead Product(s) : LCAR-HL30 Cell

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Recipient : Ruijin Hospital

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          06

                          ChemOutsourcing
                          Not Confirmed
                          ChemOutsourcing
                          Not Confirmed

                          Lead Product(s) : LCAR-M61S Cell

                          Therapeutic Area : Oncology

                          Study Phase : Undisclosed

                          Recipient : The First Affiliated Hospital with Nanjing Medical University

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : Undisclosed

                          Product Name : Undisclosed

                          Product Type : Cell and Gene therapy

                          Upfront Cash : Inapplicable

                          June 25, 2024

                          Lead Product(s) : LCAR-M61S Cell

                          Therapeutic Area : Oncology

                          Highest Development Status : Undisclosed

                          Recipient : The First Affiliated Hospital with Nanjing Medical University

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          07

                          ChemOutsourcing
                          Not Confirmed
                          ChemOutsourcing
                          Not Confirmed

                          Lead Product(s) : LUCAR-G39D Cell

                          Therapeutic Area : Oncology

                          Study Phase : Phase I

                          Recipient : Tianjin Medical University Cancer Institute and Hospital

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : Undisclosed

                          Product Name : Undisclosed

                          Product Type : Cell and Gene therapy

                          Upfront Cash : Inapplicable

                          May 02, 2024

                          Lead Product(s) : LUCAR-G39D Cell

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Recipient : Tianjin Medical University Cancer Institute and Hospital

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          08

                          ChemOutsourcing
                          Not Confirmed
                          ChemOutsourcing
                          Not Confirmed

                          Details : Carvykti (ciltacabtagene autoleucel) is an FDA-approved, BCMA-directed T cell immunotherapy for treating relapsed or refractory multiple myeloma in adult patients, with promising outcomes.

                          Product Name : Carvykti

                          Product Type : Cell and Gene therapy

                          Upfront Cash : Inapplicable

                          April 22, 2024

                          Lead Product(s) : Ciltacabtagene Autoleucel

                          Therapeutic Area : Oncology

                          Highest Development Status : Approved FDF

                          Sponsor : Johnson & Johnson Innovative Medicine

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          09

                          ChemOutsourcing
                          Not Confirmed
                          ChemOutsourcing
                          Not Confirmed

                          Lead Product(s) : LUCAR-G39P Cell

                          Therapeutic Area : Oncology

                          Study Phase : Phase I

                          Recipient : The First Affiliated Hospital with Nanjing Medical University

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : Undisclosed

                          Product Name : Undisclosed

                          Product Type : Cell and Gene therapy

                          Upfront Cash : Inapplicable

                          March 06, 2024

                          Lead Product(s) : LUCAR-G39P Cell

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Recipient : The First Affiliated Hospital with Nanjing Medical University

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          10

                          ChemOutsourcing
                          Not Confirmed
                          ChemOutsourcing
                          Not Confirmed

                          Details : Under agreement, Legend Biotech will conduct a Phase 1 clinical trial for its autologous CAR-T cell therapy candidate, LB2102 in the U.S. Novartis will conduct development for the licensed products.

                          Product Name : Undisclosed

                          Product Type : Cell and Gene therapy

                          Upfront Cash : $100.0 million

                          March 01, 2024

                          Lead Product(s) : LB2102

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Novartis Pharmaceuticals Corporation

                          Deal Size : $1,110.0 million

                          Deal Type : Licensing Agreement

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