
Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target

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Lead Product(s) : N-Methyl Amisulpride
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase II
Sponsor : Leerink Partners
Deal Size : $228.5 million
Deal Type : Public Offering
LB Pharmaceuticals eyes $228M in IPO cash
Details : LB Pharma plans to use the proceeds to advance its oral schizophrenia candidate LB-102, a modified version of amisulpride, a dopamine inhibitor.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Undisclosed
September 08, 2025
Lead Product(s) : N-Methyl Amisulpride
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase II
Sponsor : Leerink Partners
Deal Size : $228.5 million
Deal Type : Public Offering

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Lead Product(s) : Lb-102
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : $100.0 million
Deal Type : Public Offering
Biotech Finally Has an IPO After Months-Long Freeze
Details : The biotech will use the proceeds from the raise to support the entry of lead asset LB-102, a potent antagonist of dopamine D2/3 and 5HT7 receptors, into Phase III testing for schizophrenia.
Product Name : LB-102
Product Type : Miscellaneous
Upfront Cash : Undisclosed
August 25, 2025
Lead Product(s) : Lb-102
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : $100.0 million
Deal Type : Public Offering

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Lead Product(s) : N-Methyl Amisulpride
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Segal Trials Leads Phase 2 Schizophrenia Trial of LB-102 Toward Primary Endpoint
Details : LB-102 is a modified version of amisulpride, a dopamine inhibitor, small molecule drug candidate. It is being evaluated for the treatment of adult patients with acute schizophrenia.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
January 22, 2025
Lead Product(s) : N-Methyl Amisulpride
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : N-Methyl Amisulpride
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
LB Pharma's Twist on Old Sanofi Drug Passes Schizophrenia Test, Teeing up Phase 3 Push
Details : LB-102 is a modified version of amisulpride, a dopamine inhibitor, small molecule drug candidate. It is being evaluated for the treatment of adult patients with acute schizophrenia.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
January 08, 2025
Lead Product(s) : N-Methyl Amisulpride
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : N-Methyl Amisulpride
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : $75.0 million
Deal Type : Series C Financing
LB Pharmaceuticals Closes $75M Series C as it Begins Ph II Schizophrenia Trial
Details : The net proceeds from the proposed financed will focus on the development of LB-102, which is an N-methylated analogue of amisulpride under development to treat schizophrenia.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Undisclosed
January 24, 2024
Lead Product(s) : N-Methyl Amisulpride
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : $75.0 million
Deal Type : Series C Financing

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Lead Product(s) : Lb-102
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : LB-102 is a Other Small Molecule drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Schizophrenia.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
December 21, 2023
Lead Product(s) : Lb-102
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : N-Methyl Amisulpride
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
LB Announces Publication of Phase 1 Clinical Study of LB-102
Details : LB-102, a more lipophilic version of amisulpride, was designed to improve on amisulpride’s notoriously poor membrane (BBB) permeability while matching amisulpride’s binding affinity to the D2/D3 and 5HT7 receptors (critical to the treatment of schizo...
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
July 19, 2022
Lead Product(s) : N-Methyl Amisulpride
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : N-Methyl Amisulpride
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : LB-102, or N-methyl amisulpride, is a patented derivative of amisulpride, a dopamine/5-HT7 antagonist successfully used to treat schizophrenia in Europe for decades.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
October 04, 2021
Lead Product(s) : N-Methyl Amisulpride
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Lb-102
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase I
Sponsor : Washington University School of Medicine
Deal Size : Inapplicable
Deal Type : Inapplicable
Receptor Occupancy of LB-102 Using Positron Emission Tomography (PET) in Healthy Volunteers
Details : LB-102 is a Other Small Molecule drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Schizophrenia.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
October 19, 2020
Lead Product(s) : Lb-102
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase I
Sponsor : Washington University School of Medicine
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : N-Methyl Amisulpride
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : $10.0 million
Deal Type : Financing
LB Pharmaceuticals Inc Secures $10.0 Million in Additional Financing
Details : Proceeds to enable the Company’s continued clinical development of LB-102 for the treatment of schizophrenia.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Undisclosed
September 25, 2020
Lead Product(s) : N-Methyl Amisulpride
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : $10.0 million
Deal Type : Financing
