Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : LASN01
Therapeutic Area : Immunology
Study Phase : Phase I
Sponsor : Frazier Life Sciences
Deal Size : $85.0 million
Deal Type : Series B Financing
Details : The net proceeds from will support the LASN01, a first-in-class monoclonal antibody targeting the receptor for IL-11, clinical program and advance IND-enabling activities for LASN500, a highly potent, first-in-class monoclonal antibody targeting the IL-1...
Product Name : LASN01
Product Type : Antibody
Upfront Cash : Undisclosed
December 19, 2023
Lead Product(s) : LASN01
Therapeutic Area : Immunology
Highest Development Status : Phase I
Sponsor : Frazier Life Sciences
Deal Size : $85.0 million
Deal Type : Series B Financing
Lead Product(s) : LASN01
Therapeutic Area : Pulmonary/Respiratory Diseases
Study Phase : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : LASN01, a best-in-class monoclonal antibody targeting IL-11 receptor (IL-11R), is a central mediator of fibrosis and blocking its activity has the potential to be safer than and additive to other anti-fibrotic therapeutic approaches.
Product Name : LASN01
Product Type : Antibody
Upfront Cash : Inapplicable
June 15, 2022
Lead Product(s) : LASN01
Therapeutic Area : Pulmonary/Respiratory Diseases
Highest Development Status : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : LASN01
Therapeutic Area : Pulmonary/Respiratory Diseases
Study Phase : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : In vitro assays demonstrated potent blockade of IL-11-stimulated signaling by LASN01 and inhibition of TGF-β-stimulated collagen expression by patient-derived IPF fibroblasts. In ex vivo assays using normal human lung tissue.
Product Name : LASN01
Product Type : Antibody
Upfront Cash : Inapplicable
May 17, 2022
Lead Product(s) : LASN01
Therapeutic Area : Pulmonary/Respiratory Diseases
Highest Development Status : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : LASN01
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Frazier Healthcare Partners
Deal Size : $31.0 million
Deal Type : Series A Financing
Details : Proceeds from the financing to be used to develop antibodies as potential treatments for fibrosis. Lassen Therapeutics is developing LASN01, a best-in-class monoclonal antibody targeting IL-11 receptor alpha (IL-11R).
Product Name : LASN01
Product Type : Antibody
Upfront Cash : Undisclosed
June 17, 2020
Lead Product(s) : LASN01
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Frazier Healthcare Partners
Deal Size : $31.0 million
Deal Type : Series A Financing