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    [{"orgOrder":0,"company":"Lassen Therapeutics","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Immunology","country":"U.S.A","productType":"Antibody","year":"2024","type":"Inapplicable","leadProduct":"LASN01","moa":"IL-11-alpha receptor","graph1":"Immunology","graph2":"Phase II","graph3":"Lassen Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Lassen Therapeutics \/ Inapplicable","highestDevelopmentStatusID":"8","companyTruncated":"Lassen Therapeutics \/ Inapplicable"},{"orgOrder":0,"company":"Lassen Therapeutics","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Pulmonary\/Respiratory Diseases","country":"U.S.A","productType":"Antibody","year":"2022","type":"Inapplicable","leadProduct":"LASN01","moa":"IL-11-alpha receptor","graph1":"Pulmonary\/Respiratory Diseases","graph2":"Phase I\/ Phase II","graph3":"Lassen Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Respiratory Diseases","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Lassen Therapeutics \/ Inapplicable","highestDevelopmentStatusID":"7","companyTruncated":"Lassen Therapeutics \/ Inapplicable"},{"orgOrder":0,"company":"Lassen Therapeutics","sponsor":"Frazier Life Sciences","pharmaFlowCategory":"D","therapeuticArea":"Immunology","country":"U.S.A","productType":"Antibody","year":"2023","type":"Series B Financing","leadProduct":"LASN01","moa":"IL-11-alpha receptor","graph1":"Immunology","graph2":"Phase II","graph3":"Lassen Therapeutics","amount2":0.089999999999999997,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Immunology","amount2New":0.089999999999999997,"dosageForm":"Injection","sponsorNew":"Lassen Therapeutics \/ Frazier Life Sciences","highestDevelopmentStatusID":"8","companyTruncated":"Lassen Therapeutics \/ Frazier Life Sciences"},{"orgOrder":0,"company":"Lassen Therapeutics","sponsor":"Cedars-Sinai","pharmaFlowCategory":"D","therapeuticArea":"Pulmonary\/Respiratory Diseases","country":"U.S.A","productType":"Antibody","year":"2021","type":"Collaboration","leadProduct":"LASN01","moa":"IL-11-alpha receptor","graph1":"Pulmonary\/Respiratory Diseases","graph2":"Preclinical","graph3":"Lassen Therapeutics","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Respiratory Diseases","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Lassen Therapeutics \/ Lassen Therapeutics","highestDevelopmentStatusID":"4","companyTruncated":"Lassen Therapeutics \/ Lassen Therapeutics"},{"orgOrder":0,"company":"Lassen Therapeutics","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Pulmonary\/Respiratory Diseases","country":"U.S.A","productType":"Antibody","year":"2022","type":"Inapplicable","leadProduct":"LASN01","moa":"IL-11-alpha receptor","graph1":"Pulmonary\/Respiratory Diseases","graph2":"Preclinical","graph3":"Lassen Therapeutics","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Respiratory Diseases","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Lassen Therapeutics \/ Inapplicable","highestDevelopmentStatusID":"4","companyTruncated":"Lassen Therapeutics \/ Inapplicable"},{"orgOrder":0,"company":"Lassen Therapeutics","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Pulmonary\/Respiratory Diseases","country":"U.S.A","productType":"Antibody","year":"2022","type":"Inapplicable","leadProduct":"LASN01","moa":"IL-11-alpha receptor","graph1":"Pulmonary\/Respiratory Diseases","graph2":"Preclinical","graph3":"Lassen Therapeutics","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Respiratory Diseases","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Lassen Therapeutics \/ Inapplicable","highestDevelopmentStatusID":"4","companyTruncated":"Lassen Therapeutics \/ Inapplicable"},{"orgOrder":0,"company":"Lassen Therapeutics","sponsor":"Frazier Healthcare Partners","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Antibody","year":"2020","type":"Series A Financing","leadProduct":"LASN01","moa":"IL-11-alpha receptor","graph1":"Oncology","graph2":"Preclinical","graph3":"Lassen Therapeutics","amount2":0.029999999999999999,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0.029999999999999999,"dosageForm":"Undisclosed","sponsorNew":"Lassen Therapeutics \/ Frazier Healthcare Partners","highestDevelopmentStatusID":"4","companyTruncated":"Lassen Therapeutics \/ Frazier Healthcare Partners"}]

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                            01

                            Lassen Therapeutics

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                            Lead Product(s) : LASN01

                            Therapeutic Area : Immunology

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            A Study to Evaluate the Efficacy and Safety of LASN01 in Patients With Thyroid Eye Disease

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Antibody

                            Upfront Cash : Inapplicable

                            January 26, 2024

                            Lead Product(s) : LASN01

                            Therapeutic Area : Immunology

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            02

                            Lassen Therapeutics

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                            Lassen Therapeutics

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                            Lead Product(s) : LASN01

                            Therapeutic Area : Immunology

                            Study Phase : Phase I

                            Sponsor : Frazier Life Sciences

                            Deal Size : $85.0 million

                            Deal Type : Series B Financing

                            DEALS_DEV arrow-down

                            Lassen Therapeutics Announces Closing of Oversubscribed $85 Million Series B Financing and Announces First Pat...

                            Details : The net proceeds from will support the LASN01, a first-in-class monoclonal antibody targeting the receptor for IL-11, clinical program and advance IND-enabling activities for LASN500, a highly potent, first-in-class monoclonal antibody targeting the IL-1...

                            Product Name : Undisclosed

                            Product Type : Antibody

                            Upfront Cash : Undisclosed

                            December 19, 2023

                            Lead Product(s) : LASN01

                            Therapeutic Area : Immunology

                            Highest Development Status : Phase I

                            Sponsor : Frazier Life Sciences

                            Deal Size : $85.0 million

                            Deal Type : Series B Financing

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                            03

                            Lassen Therapeutics

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                            Lead Product(s) : LASN01

                            Therapeutic Area : Pulmonary/Respiratory Diseases

                            Study Phase : Preclinical

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Lassen Therapeutics Presents New Preclinical Data on IL-11 Receptor-blocking as a Novel Therapeutic Approach f...

                            Details : LASN01, a best-in-class monoclonal antibody targeting IL-11 receptor (IL-11R), is a central mediator of fibrosis and blocking its activity has the potential to be safer than and additive to other anti-fibrotic therapeutic approaches.

                            Product Name : Undisclosed

                            Product Type : Antibody

                            Upfront Cash : Inapplicable

                            June 15, 2022

                            Lead Product(s) : LASN01

                            Therapeutic Area : Pulmonary/Respiratory Diseases

                            Highest Development Status : Preclinical

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            04

                            Lassen Therapeutics

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                            Lassen Therapeutics

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                            Lead Product(s) : LASN01

                            Therapeutic Area : Pulmonary/Respiratory Diseases

                            Study Phase : Preclinical

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Lassen Therapeutics Presents Data Demonstrating Preclinical Anti-fibrotic Effect of LASN01, a Novel IL-11 Rece...

                            Details : In vitro assays demonstrated potent blockade of IL-11-stimulated signaling by LASN01 and inhibition of TGF-β-stimulated collagen expression by patient-derived IPF fibroblasts. In ex vivo assays using normal human lung tissue.

                            Product Name : Undisclosed

                            Product Type : Antibody

                            Upfront Cash : Inapplicable

                            May 17, 2022

                            Lead Product(s) : LASN01

                            Therapeutic Area : Pulmonary/Respiratory Diseases

                            Highest Development Status : Preclinical

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            05

                            Lassen Therapeutics

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                            Lead Product(s) : LASN01

                            Therapeutic Area : Pulmonary/Respiratory Diseases

                            Study Phase : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            A Study to Evaluate the Safety, Preliminary Efficacy, and Pharmacokinetic Properties of LASN01 in Healthy Subj...

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Antibody

                            Upfront Cash : Inapplicable

                            April 15, 2022

                            Lead Product(s) : LASN01

                            Therapeutic Area : Pulmonary/Respiratory Diseases

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            06

                            Lassen Therapeutics

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                            Lead Product(s) : LASN01

                            Therapeutic Area : Pulmonary/Respiratory Diseases

                            Study Phase : Preclinical

                            Recipient : Cedars-Sinai

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            Lassen Therapeutics Collaborates with Cedars Sinai to Study the Role of IL-11 Signaling and Inhibition in Lung...

                            Details : The collaboration will study the role of IL-11 signaling and its inhibition in lung fibrosis, particularly idiopathic pulmonary fibrosis, and the potential therapeutic effect of monoclonal antibodies, which includes LASN01, that block this signaling in p...

                            Product Name : Undisclosed

                            Product Type : Antibody

                            Upfront Cash : Undisclosed

                            March 25, 2021

                            Lead Product(s) : LASN01

                            Therapeutic Area : Pulmonary/Respiratory Diseases

                            Highest Development Status : Preclinical

                            Recipient : Cedars-Sinai

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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                            07

                            Lassen Therapeutics

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                            Lead Product(s) : LASN01

                            Therapeutic Area : Oncology

                            Study Phase : Preclinical

                            Sponsor : Frazier Healthcare Partners

                            Deal Size : $31.0 million

                            Deal Type : Series A Financing

                            DEALS_DEV arrow-down

                            Lassen Therapeutics Launches to Discover and Develop Novel Antibody Therapeutics to Treat Fibrosis and Oncolog...

                            Details : Proceeds from the financing to be used to develop antibodies as potential treatments for fibrosis. Lassen Therapeutics is developing LASN01, a best-in-class monoclonal antibody targeting IL-11 receptor alpha (IL-11R).

                            Product Name : Undisclosed

                            Product Type : Antibody

                            Upfront Cash : Undisclosed

                            June 17, 2020

                            Lead Product(s) : LASN01

                            Therapeutic Area : Oncology

                            Highest Development Status : Preclinical

                            Sponsor : Frazier Healthcare Partners

                            Deal Size : $31.0 million

                            Deal Type : Series A Financing

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