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Find Clinical Drug Pipeline Developments & Deals by Lassen Therapeutics

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                          Top Deals by Deal Size (USD bn)

                          01

                          STLE Annual Meeting
                          Not Confirmed
                          STLE Annual Meeting
                          Not Confirmed

                          Details : The net proceeds from will support the LASN01, a first-in-class monoclonal antibody targeting the receptor for IL-11, clinical program and advance IND-enabling activities for LASN500, a highly potent, first-in-class monoclonal antibody targeting the IL-1...

                          Product Name : LASN01

                          Product Type : Antibody

                          Upfront Cash : Undisclosed

                          December 19, 2023

                          Lead Product(s) : LASN01

                          Therapeutic Area : Immunology

                          Highest Development Status : Phase I

                          Sponsor : Frazier Life Sciences

                          Deal Size : $85.0 million

                          Deal Type : Series B Financing

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                          02

                          STLE Annual Meeting
                          Not Confirmed
                          STLE Annual Meeting
                          Not Confirmed

                          Details : LASN01, a best-in-class monoclonal antibody targeting IL-11 receptor (IL-11R), is a central mediator of fibrosis and blocking its activity has the potential to be safer than and additive to other anti-fibrotic therapeutic approaches.

                          Product Name : LASN01

                          Product Type : Antibody

                          Upfront Cash : Inapplicable

                          June 15, 2022

                          Lead Product(s) : LASN01

                          Therapeutic Area : Pulmonary/Respiratory Diseases

                          Highest Development Status : Preclinical

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          03

                          STLE Annual Meeting
                          Not Confirmed
                          STLE Annual Meeting
                          Not Confirmed

                          Details : In vitro assays demonstrated potent blockade of IL-11-stimulated signaling by LASN01 and inhibition of TGF-β-stimulated collagen expression by patient-derived IPF fibroblasts. In ex vivo assays using normal human lung tissue.

                          Product Name : LASN01

                          Product Type : Antibody

                          Upfront Cash : Inapplicable

                          May 17, 2022

                          Lead Product(s) : LASN01

                          Therapeutic Area : Pulmonary/Respiratory Diseases

                          Highest Development Status : Preclinical

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          04

                          STLE Annual Meeting
                          Not Confirmed
                          STLE Annual Meeting
                          Not Confirmed

                          Details : Proceeds from the financing to be used to develop antibodies as potential treatments for fibrosis. Lassen Therapeutics is developing LASN01, a best-in-class monoclonal antibody targeting IL-11 receptor alpha (IL-11R).

                          Product Name : LASN01

                          Product Type : Antibody

                          Upfront Cash : Undisclosed

                          June 17, 2020

                          Lead Product(s) : LASN01

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : Frazier Healthcare Partners

                          Deal Size : $31.0 million

                          Deal Type : Series A Financing

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