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    [{"orgOrder":0,"company":"LadRx","sponsor":"XOMA","pharmaFlowCategory":"D","therapeuticArea":"Rare Diseases and Disorders","country":"U.S.A","productType":"Miscellaneous","year":"2024","type":"Agreement","leadProduct":"Arimoclomol Citrate","moa":"HSF-1 pathway","graph1":"Rare Diseases and Disorders","graph2":"Phase II\/ Phase III","graph3":"LadRx","amount2":0.059999999999999998,"highestDevelopmentShortName":"Ph II\/III","therapeuticAreaShortName":"Rare Diseases","amount2New":0.059999999999999998,"dosageForm":"Capsule","sponsorNew":"LadRx \/ XOMA","highestDevelopmentStatusID":"9","companyTruncated":"LadRx \/ XOMA"},{"orgOrder":0,"company":"LadRx","sponsor":"ImmunityBio","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Cytotoxic Drug","year":"2024","type":"Termination","leadProduct":"Aldoxorubicin HCl","moa":"TOP2","graph1":"Oncology","graph2":"Phase III","graph3":"LadRx","amount2":0.35999999999999999,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Oncology","amount2New":0.35999999999999999,"dosageForm":"Infusion","sponsorNew":"LadRx \/ ImmunityBio","highestDevelopmentStatusID":"10","companyTruncated":"LadRx \/ ImmunityBio"},{"orgOrder":0,"company":"LadRx","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Cytotoxic Drug","year":"2024","type":"Inapplicable","leadProduct":"Aldoxorubicin HCl","moa":"TOP2","graph1":"Oncology","graph2":"Phase III","graph3":"LadRx","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Infusion","sponsorNew":"LadRx \/ Undisclosed","highestDevelopmentStatusID":"10","companyTruncated":"LadRx \/ Undisclosed"},{"orgOrder":0,"company":"LadRx","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Cytotoxic Drug","year":"2023","type":"Inapplicable","leadProduct":"Aldoxorubicin HCl","moa":"TOP2","graph1":"Oncology","graph2":"Phase II","graph3":"LadRx","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"LadRx \/ Undisclosed","highestDevelopmentStatusID":"8","companyTruncated":"LadRx \/ Undisclosed"},{"orgOrder":0,"company":"LadRx","sponsor":"XOMA","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Miscellaneous","year":"2023","type":"Financing","leadProduct":"AE-Keto-Sulf07","moa":"Tubulin","graph1":"Oncology","graph2":"IND Enabling","graph3":"LadRx","amount2":0.01,"highestDevelopmentShortName":"IND","therapeuticAreaShortName":"Oncology","amount2New":0.01,"dosageForm":"Undisclosed","sponsorNew":"LadRx \/ XOMA","highestDevelopmentStatusID":"5","companyTruncated":"LadRx \/ XOMA"}]

    Find Clinical Drug Pipeline Developments & Deals by LadRx

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                            01

                            LadRx

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                            Lead Product(s) : Aldoxorubicin HCl

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            LadRx Planning NDA Submission Under 505(b)(2) for Aldoxorubicin and Other Updates

                            Details : INNO-206 (aldoxorubicin), a rationally-engineered cytotoxic which delivers well-established anti-cancer agent, doxorubicin, into the tumor. It is being evaluated for treatment of soft tissue sarcoma.

                            Product Name : Undisclosed

                            Product Type : Cytotoxic Drug

                            Upfront Cash : Inapplicable

                            December 11, 2024

                            Lead Product(s) : Aldoxorubicin HCl

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            02

                            LadRx

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                            LadRx

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                            Lead Product(s) : Aldoxorubicin HCl

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Sponsor : ImmunityBio

                            Deal Size : $356.0 million

                            Deal Type : Termination

                            DEALS_DEV arrow-down

                            LadRx and ImmunityBio Mutually Agree to Terminate Aldoxorubicin License

                            Details : With the termination, LadRx regains control of INNO-206 (aldoxorubicin), a rationally-engineered cytotoxic which delivers well-established anti-cancer agent, doxorubicin, into the tumor.

                            Product Name : Undisclosed

                            Product Type : Cytotoxic Drug

                            Upfront Cash : Undisclosed

                            June 03, 2024

                            Lead Product(s) : Aldoxorubicin HCl

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : ImmunityBio

                            Deal Size : $356.0 million

                            Deal Type : Termination

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                            03

                            LadRx

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                            Lead Product(s) : Arimoclomol Citrate

                            Therapeutic Area : Rare Diseases and Disorders

                            Study Phase : Phase II/ Phase III

                            Sponsor : XOMA

                            Deal Size : $58.6 million

                            Deal Type : Agreement

                            DEALS_DEV arrow-down

                            FDA Accepts Zevra's Arimoclomol NDA for NPC Type C, Triggering Milestone Payment

                            Details : XOMA acquired royalty and milestone rights for LadRx Corporation’s BRX-345 (arimoclomol) for Niemann-Pick Disease Type C, and aldoxorubicin, an albumin-linked formulation of doxorubicin.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : $5.0 million

                            January 11, 2024

                            Lead Product(s) : Arimoclomol Citrate

                            Therapeutic Area : Rare Diseases and Disorders

                            Highest Development Status : Phase II/ Phase III

                            Sponsor : XOMA

                            Deal Size : $58.6 million

                            Deal Type : Agreement

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                            04

                            LadRx

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                            COMPAMED
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                            LadRx

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                            Lead Product(s) : AE-Keto-Sulf07

                            Therapeutic Area : Oncology

                            Study Phase : IND Enabling

                            Sponsor : XOMA

                            Deal Size : $11.0 million

                            Deal Type : Financing

                            DEALS_DEV arrow-down

                            LadRx Completes Non-Dilutive Financing Transaction for up to $11 Million with XOMA Corporation

                            Details : The Company expects to use the proceeds to advance its lead novel LADR-based anti-cancer drug, LADR-7 (AE-keto-sulf07) towards an IND filing with the FDA.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Undisclosed

                            June 22, 2023

                            Lead Product(s) : AE-Keto-Sulf07

                            Therapeutic Area : Oncology

                            Highest Development Status : IND Enabling

                            Sponsor : XOMA

                            Deal Size : $11.0 million

                            Deal Type : Financing

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                            05

                            LadRx

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                            Lead Product(s) : Aldoxorubicin HCl

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            LadRx Highlights Patent Issued for Its LADR Technology

                            Details : INNO-206 (aldoxorubicin) is a prodrug of doxorubicin that binds endogenous albumin after administration. The bound doxorubicin is released in the acidic environment of the tumor cell through cleavage of an acid sensitive linker and expresses antitumor ef...

                            Product Name : Undisclosed

                            Product Type : Cytotoxic Drug

                            Upfront Cash : Inapplicable

                            March 27, 2023

                            Lead Product(s) : Aldoxorubicin HCl

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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