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Find Clinical Drug Pipeline Developments & Deals by Kynexis Therapeutics

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                          Top Deals by Deal Size (USD bn)

                          01

                          BioFit
                          Not Confirmed
                          BioFit
                          Not Confirmed

                          Details : The partnership with KYN-5356 aims to advance the treatment of neurological disorders by targeting KAT2.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Undisclosed

                          November 14, 2025

                          Lead Product(s) : KYN-5356

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase II

                          Recipient : Cognision

                          Deal Size : Undisclosed

                          Deal Type : Partnership

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                          02

                          BioFit
                          Not Confirmed
                          BioFit
                          Not Confirmed

                          Details : KYN-5356 is a Small Molecule drug candidate drug candidate, which is currently being evaluated in Phase II clinical studies for the treatment of Cognitive Dysfunction-associated with Schizophrenia.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          September 24, 2025

                          Lead Product(s) : KYN-5356

                          Therapeutic Area : Psychiatry/Psychology

                          Highest Development Status : Phase II

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          03

                          BioFit
                          Not Confirmed
                          BioFit
                          Not Confirmed

                          Details : KYN-5356 is a small molecule targeting a key enzyme in the kynurenine pathway known as KAT-II. It is being evaluated for the treatment of cognitive impairment associated with schizophrenia.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          December 17, 2024

                          Lead Product(s) : KYN-5356

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase I

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          04

                          BioFit
                          Not Confirmed
                          BioFit
                          Not Confirmed

                          Details : KYN-5356 is a Other Small Molecule drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Cognitive Dysfunction.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          January 25, 2024

                          Lead Product(s) : KYN-5356

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase I

                          Sponsor : Parexel

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          05

                          BioFit
                          Not Confirmed
                          BioFit
                          Not Confirmed

                          Details : KYN-5356 is a clinical-stage small molecule targeting KAT-II in the kynurenine pathway. It is being evaluated in Phase 1 for cognitive impairment associated with schizophrenia.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          January 04, 2024

                          Lead Product(s) : KYN-5356

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase I

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          06

                          BioFit
                          Not Confirmed
                          BioFit
                          Not Confirmed

                          Details : Through the proceeds, Kynexis will advance its lead therapeutic candidate, KYN-5356, a potential first-in-class KAT-II inhibitor for the treatment of cognitive impairment associated with schizophrenia (CIAS), toward clinical development.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Undisclosed

                          November 07, 2023

                          Lead Product(s) : KYN-5356

                          Therapeutic Area : Neurology

                          Highest Development Status : Preclinical

                          Sponsor : Forbion

                          Deal Size : $62.1 million

                          Deal Type : Series A Financing

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