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    [{"orgOrder":0,"company":"Knight Therapeutics","sponsor":"Novartis Pharmaceuticals Corporation","pharmaFlowCategory":"D","therapeuticArea":"Neurology","country":"SWITZERLAND","productType":"Miscellaneous","year":"2021","type":"Acquisition","leadProduct":"Rivastigmine Tartrate","moa":"Cholinesterases; ACHE & BCHE","graph1":"Neurology","graph2":"Approved FDF","graph3":"Knight Therapeutics","amount2":0.17999999999999999,"highestDevelopmentShortName":"Approved FDF","therapeuticAreaShortName":"Neurology","amount2New":0.17999999999999999,"dosageForm":"Capsule","sponsorNew":"Knight Therapeutics \/ Knight Therapeutics","highestDevelopmentStatusID":"15","companyTruncated":"Knight Therapeutics \/ Knight Therapeutics"},{"orgOrder":0,"company":"Knight Therapeutics","sponsor":"Novartis Pharmaceuticals Corporation","pharmaFlowCategory":"D","therapeuticArea":"Neurology","country":"SWITZERLAND","productType":"Miscellaneous","year":"2021","type":"Acquisition","leadProduct":"Rivastigmine 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Therapeutics","highestDevelopmentStatusID":"15","companyTruncated":"Knight Therapeutics \/ Knight Therapeutics"},{"orgOrder":0,"company":"Knight Therapeutics","sponsor":"Rigel Pharmaceuticals","pharmaFlowCategory":"DU","therapeuticArea":"Immunology","country":"CANADA","productType":"Miscellaneous","year":"2024","type":"Inapplicable","leadProduct":"Fostamatinib Disodium Hexahydrate","moa":"Tyrosine-protein kinase SYK","graph1":"Immunology","graph2":"Approved FDF","graph3":"Knight Therapeutics","amount2":0,"highestDevelopmentShortName":"Approved FDF","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"Tablet, Film Coated","sponsorNew":"Knight Therapeutics \/ Rigel Pharmaceuticals","highestDevelopmentStatusID":"15","companyTruncated":"Knight Therapeutics \/ Rigel Pharmaceuticals"},{"orgOrder":0,"company":"Knight Therapeutics","sponsor":"Rigel Pharmaceuticals","pharmaFlowCategory":"DU","therapeuticArea":"Immunology","country":"CANADA","productType":"Miscellaneous","year":"2024","type":"Inapplicable","leadProduct":"Fostamatinib Disodium Hexahydrate","moa":"Tyrosine-protein kinase SYK","graph1":"Immunology","graph2":"Approved FDF","graph3":"Knight Therapeutics","amount2":0,"highestDevelopmentShortName":"Approved FDF","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"Tablet, Film Coated","sponsorNew":"Knight Therapeutics \/ Rigel Pharmaceuticals","highestDevelopmentStatusID":"15","companyTruncated":"Knight Therapeutics \/ Rigel Pharmaceuticals"}]

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                            01

                            Knight Therapeutics

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                            AIChE Annual Meeting
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                            Knight Therapeutics

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                            Lead Product(s) : Fostamatinib Disodium Hexahydrate

                            Therapeutic Area : Immunology

                            Study Phase : Approved FDF

                            Sponsor : Rigel Pharmaceuticals

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Knight Therapeutics Announces Regulatory Approval of TAVALISSE® in Mexico

                            Details : Tavalisse (fostamatinib disodium hexahydrate) is a kinase inhibitor indicated for the treatment of thrombocytopenia in adult patients with chronic immune thrombocytopenia (ITP).

                            Product Name : Tavalisse

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            December 12, 2024

                            Lead Product(s) : Fostamatinib Disodium Hexahydrate

                            Therapeutic Area : Immunology

                            Highest Development Status : Approved FDF

                            Sponsor : Rigel Pharmaceuticals

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            02

                            Knight Therapeutics

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                            AIChE Annual Meeting
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                            Lead Product(s) : Fostamatinib Disodium Hexahydrate

                            Therapeutic Area : Immunology

                            Study Phase : Approved FDF

                            Sponsor : Rigel Pharmaceuticals

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Knight Therapeutics Announces Regulatory Submission of Fostamatinib in Brazil

                            Details : Tavalisse (fostamatinib disodium hexahydrate) is a kinase inhibitor indicated for the treatment of thrombocytopenia in adult patients with chronic immune thrombocytopenia (ITP).

                            Product Name : Tavalisse

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            February 21, 2024

                            Lead Product(s) : Fostamatinib Disodium Hexahydrate

                            Therapeutic Area : Immunology

                            Highest Development Status : Approved FDF

                            Sponsor : Rigel Pharmaceuticals

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

                            Knight Therapeutics

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                            AIChE Annual Meeting
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                            Knight Therapeutics

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                            AIChE Annual Meeting
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                            Lead Product(s) : Isavuconazonium Sulfate

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Approved FDF

                            Recipient : Basilea Pharmaceutica

                            Deal Size : Undisclosed

                            Deal Type : Licensing Agreement

                            DEALS_DEV arrow-down

                            Cresemba® Sales in Latin America Trigger First Sales Milestone Payment to Basilea

                            Details : Knight will commercialize Cresemba (isavuconazole sulfate) in Latin America, an azole antifungal for treating adult patients with invasive aspergillosis, licensed for regional distribution.

                            Product Name : Cresemba

                            Product Type : Miscellaneous

                            Upfront Cash : $11.2 million

                            January 19, 2024

                            Lead Product(s) : Isavuconazonium Sulfate

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Approved FDF

                            Recipient : Basilea Pharmaceutica

                            Deal Size : Undisclosed

                            Deal Type : Licensing Agreement

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                            04

                            Knight Therapeutics

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                            AIChE Annual Meeting
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                            Knight Therapeutics

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                            AIChE Annual Meeting
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                            Lead Product(s) : Triptorelin Pamoate

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Recipient : Ottawa Hospital Research Institute

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Dose Escalation For INtraprostatic LEsions

                            Details : Triptorelin is a Protein drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Prostatic Neoplasms.

                            Product Name : Undisclosed

                            Product Type : Protein

                            Upfront Cash : Inapplicable

                            May 09, 2023

                            Lead Product(s) : Triptorelin Pamoate

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Recipient : Ottawa Hospital Research Institute

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            05

                            Knight Therapeutics

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                            AIChE Annual Meeting
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                            Knight Therapeutics

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                            Lead Product(s) : Rivastigmine Tartrate

                            Therapeutic Area : Neurology

                            Study Phase : Approved FDF

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Knight Therapeutics Assumes Commercial Activities and Re-Launches Exelon in Brazil

                            Details : Exelon (rivastigmine tartrate) is an oral acetylcholinesterase inhibitor, which is approved for the treatment of mild to moderately severe dementia in people with Alzheimer's disease and Parkinson's disease..

                            Product Name : Exelon

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            August 15, 2022

                            Lead Product(s) : Rivastigmine Tartrate

                            Therapeutic Area : Neurology

                            Highest Development Status : Approved FDF

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            06

                            Knight Therapeutics

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                            AIChE Annual Meeting
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                            Knight Therapeutics

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                            Lead Product(s) : Rivastigmine Tartrate

                            Therapeutic Area : Neurology

                            Study Phase : Approved FDF

                            Sponsor : Novartis Pharmaceuticals Corporation

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Knight Therapeutics Assumes Commercial Activities and Re-Launches Exelon in Brazil

                            Details : Exelon Patch (rivastigmine transdermal system) is a class of medications called cholinesterase inhibitors, which is used to manage and treat neurodegenerative disease, specifically dementia, in patients with Alzheimer and Parkinson disease.

                            Product Name : Exelon

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            August 15, 2022

                            Lead Product(s) : Rivastigmine Tartrate

                            Therapeutic Area : Neurology

                            Highest Development Status : Approved FDF

                            Sponsor : Novartis Pharmaceuticals Corporation

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            Knight Therapeutics

                            Canada arrow
                            AIChE Annual Meeting
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                            Knight Therapeutics

                            Canada arrow
                            AIChE Annual Meeting
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                            Lead Product(s) : Rivastigmine Tartrate

                            Therapeutic Area : Neurology

                            Study Phase : Approved FDF

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Knight Therapeutics Assumes Commercial Activities for Exelon in Colombia

                            Details : Exelon (rivastigmine tartrate) is an oral acetylcholinesterase inhibitor, which is approved for the treatment of mild to moderately severe dementia in people with Alzheimer's disease and Parkinson's disease..

                            Product Name : Exelon

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            June 01, 2022

                            Lead Product(s) : Rivastigmine Tartrate

                            Therapeutic Area : Neurology

                            Highest Development Status : Approved FDF

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            08

                            Knight Therapeutics

                            Canada arrow
                            AIChE Annual Meeting
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                            Knight Therapeutics

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                            AIChE Annual Meeting
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                            Lead Product(s) : Fostamatinib Disodium Hexahydrate

                            Therapeutic Area : Immunology

                            Study Phase : Approved FDF

                            Recipient : Rigel Pharmaceuticals

                            Deal Size : Undisclosed

                            Deal Type : Licensing Agreement

                            DEALS_DEV arrow-down

                            Knight Enters into Exclusive License Agreements with Rigel to Commercialize Fostamatinib

                            Details : Knight will be responsible for the development and commercialization rights in Latin America for Tavalisse (fostamatinib), a spleen tyrosine kinase inhibitor for treating immune thrombocytopenia.

                            Product Name : Tavalisse

                            Product Type : Miscellaneous

                            Upfront Cash : Undisclosed

                            May 24, 2022

                            Lead Product(s) : Fostamatinib Disodium Hexahydrate

                            Therapeutic Area : Immunology

                            Highest Development Status : Approved FDF

                            Recipient : Rigel Pharmaceuticals

                            Deal Size : Undisclosed

                            Deal Type : Licensing Agreement

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                            09

                            Knight Therapeutics

                            Canada arrow
                            AIChE Annual Meeting
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                            Knight Therapeutics

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                            AIChE Annual Meeting
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                            Lead Product(s) : Miltefosine

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Undisclosed

                            Recipient : Profounda Pharmaceuticals

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            FDA Grants Profounda Orphan Drug Designation Approval for treatment of Treatment of Invasive Candidiasis with ...

                            Details : Miltefosine is an alkyllysophospholipid analogue drug with in vitro activity against the promastigote and amastigote stages of Leishmania species. Leishmaniasis is a parasitic disease that is found in parts of the tropics, subtropics, and southern Europ...

                            Product Name : Impavido

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            November 08, 2021

                            Lead Product(s) : Miltefosine

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Undisclosed

                            Recipient : Profounda Pharmaceuticals

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            10

                            Knight Therapeutics

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                            AIChE Annual Meeting
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                            Lead Product(s) : Rivastigmine Tartrate

                            Therapeutic Area : Neurology

                            Study Phase : Approved FDF

                            Recipient : Novartis Pharmaceuticals Corporation

                            Deal Size : $180.0 million

                            Deal Type : Acquisition

                            DEALS_DEV arrow-down

                            Knight Therapeutics Announces Closing of Previously Announced Acquisition and Exclusive License to Exelon® in...

                            Details : Knight Therapeutics has acquired exclusive rights to manufacture, market and sell Exelon® (rivastigmine Patch, Capsules and Solution) in Canada and Latin America, as well as an exclusive license to use the intellectual property and the Exelon trademark,...

                            Product Name : Exelon

                            Product Type : Miscellaneous

                            Upfront Cash : $168.0 million

                            May 26, 2021

                            Lead Product(s) : Rivastigmine Tartrate

                            Therapeutic Area : Neurology

                            Highest Development Status : Approved FDF

                            Recipient : Novartis Pharmaceuticals Corporation

                            Deal Size : $180.0 million

                            Deal Type : Acquisition

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