
Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target

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Lead Product(s) : DSP107,Atezolizumab
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : DSP107, a dual, first-in-class CD47 and 4-1BB targeting fusion protein that activates innate and adaptive immunity, is being developed in combination with atezolizumab, an anti-PD-L1 in patients with advanced solid tumors.
Product Name : Undisclosed
Product Type : Protein
Upfront Cash : Inapplicable
May 31, 2023
Lead Product(s) : DSP107,Atezolizumab
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : DSP107
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Myeloma Investment Fund
Deal Size : $59.0 million
Deal Type : Financing
Details : DSP107 is a dual-targeting fusion protein that activates innate and adaptive immunity by blocking CD47 on cancer cells and utilizing 4-1BB conditional co-stimulatory activation of T-cells.
Product Name : Undisclosed
Product Type : Protein
Upfront Cash : Undisclosed
November 17, 2022
Lead Product(s) : DSP107
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Myeloma Investment Fund
Deal Size : $59.0 million
Deal Type : Financing

A Study of Dual-SIgnaling Protein 107 (DSP107) for Patients With Hematological Malignancies
Details : DSP107 is a Protein drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Leukemia, Myeloid, Acute.
Product Name : Undisclosed
Product Type : Protein
Upfront Cash : Inapplicable
June 23, 2021

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Lead Product(s) : DSP107,Atezolizumab
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : aMoon
Deal Size : $46.5 million
Deal Type : Financing
KAHR Announces $46.5 Million Financing to Advance its Multifunctional Immunotherapeutic Pipeline
Details : Proceeds will enable further clinical development of DSP107, a first-in-class CD47x41BB targeting fusion protein, for the treatment of solid and hematological tumors and accelerate the path towards clinical development of the Company's preclinical pipeli...
Product Name : Undisclosed
Product Type : Protein
Upfront Cash : Undisclosed
June 16, 2021
Lead Product(s) : DSP107,Atezolizumab
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : aMoon
Deal Size : $46.5 million
Deal Type : Financing

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Lead Product(s) : DSP502
Therapeutic Area : Oncology
Study Phase : Preclinical
Recipient : Samsung Biologics
Deal Size : Undisclosed
Deal Type : Agreement
Details : Under the terms of the agreement, Samsung Biologics will provide its end-to-end cell line development and clinical drug substance and drug product manufacturing services as well as IND filling support for KAHR’s drug candidate DSP502, a TIGITxPD1 fusio...
Product Name : Undisclosed
Product Type : Protein
Upfront Cash : Undisclosed
June 02, 2021
Lead Product(s) : DSP502
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Recipient : Samsung Biologics
Deal Size : Undisclosed
Deal Type : Agreement

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Lead Product(s) : DSP107,Azacitidine
Therapeutic Area : Oncology
Study Phase : IND Enabling
Sponsor : Cancer Focus Fund
Deal Size : $5.0 million
Deal Type : Funding
Details : DSP107 uniquely delivers a multilayered attack by binding cancer cells and T-cells to produce a targeted synergistic effect, combining immune checkpoint inhibition with selective T-cell activation.
Product Name : Undisclosed
Product Type : Protein
Upfront Cash : Undisclosed
May 26, 2021
Lead Product(s) : DSP107,Azacitidine
Therapeutic Area : Oncology
Highest Development Status : IND Enabling
Sponsor : Cancer Focus Fund
Deal Size : $5.0 million
Deal Type : Funding

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Lead Product(s) : DSP502
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Thomas Jefferson University
Deal Size : Undisclosed
Deal Type : Collaboration
Details : Under the agreement, Thomas Jefferson University is granting KAHR an exclusive license to develop and commercialize multiple new drug candidates including DSP502, a TIGITxPD1 fusion protein, and DSP216, a LILRB2xSIRPa fusion protein for immuno-oncology.
Product Name : Undisclosed
Product Type : Protein
Upfront Cash : Undisclosed
April 01, 2021
Lead Product(s) : DSP502
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Thomas Jefferson University
Deal Size : Undisclosed
Deal Type : Collaboration

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Lead Product(s) : DSP107,Atezolizumab
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
KAHR Announces First Patient Dosed in Phase 1/2 Clinical Trial of DSP107
Details : Study to be conducted in two parts. The first part will evaluate the safety, pharmacokinetics and pharmacodynamics of DSP107 as a monotherapy and in combination with Roche's PD-L1-blocking checkpoint inhibitor atezolizumab (Tecentriq®) in patients with ...
Product Name : Undisclosed
Product Type : Protein
Upfront Cash : Inapplicable
November 12, 2020
Lead Product(s) : DSP107,Atezolizumab
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : DSP107,Atezolizumab
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Under this IND, the Company intends to initiate a Phase I/II clinical trial to evaluate the safety, pharmacokinetics and pharmacodynamics of DSP107 as a monotherapy and in combination with Roche's atezolizumab (Tecentriq®) in patients with advanced soli...
Product Name : Undisclosed
Product Type : Protein
Upfront Cash : Inapplicable
August 12, 2020
Lead Product(s) : DSP107,Atezolizumab
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : DSP107
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
A Study of DSP107 Alone and in Combination with Atezolizumab for Patients with Advanced Solid Tumors
Details : DSP107 is a Protein drug candidate, which is currently being evaluated in phase I/ phase II clinical studies for the treatment of Neoplasms.
Product Name : Undisclosed
Product Type : Protein
Upfront Cash : Inapplicable
June 22, 2020
Lead Product(s) : DSP107
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
