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Find Clinical Drug Pipeline Developments & Deals by Kadimastem

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                          01

                          Excipient World
                          Not Confirmed
                          Excipient World
                          Not Confirmed

                          Details : Kadimastem’s flagship product, AstroRx®, is comprised of a differentiated cell population of human astrocytes derived from human pluripotent stem cells and is in clinical development as a therapeutic treatment for ALS.

                          Product Name : AstroRx

                          Product Type : Cell and Gene therapy

                          Upfront Cash : Inapplicable

                          September 03, 2021

                          Lead Product(s) : Human Pluripotent Stem Cell

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          02

                          Excipient World
                          Not Confirmed
                          Excipient World
                          Not Confirmed

                          Details : The primary objective of the trial was to evaluate the safety of AstroRx®, an "off-the-shelf", clinical-grade, astrocyte cell product, developed and manufactured by the Company. The trial met its endpoints.

                          Product Name : AstroRx

                          Product Type : Cell and Gene therapy

                          Upfront Cash : Inapplicable

                          December 15, 2020

                          Lead Product(s) : Human Pluripotent Stem Cell

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          03

                          Excipient World
                          Not Confirmed
                          Excipient World
                          Not Confirmed

                          Details : Kadimastem's lead product, AstroRx®, showed a positive efficacy signal and a good safety profile in Cohort B of the Company’s Phase 1/2a clinical trial in ALS.

                          Product Name : AstroRx

                          Product Type : Cell and Gene therapy

                          Upfront Cash : Inapplicable

                          March 08, 2020

                          Lead Product(s) : Human Pluripotent Stem Cell

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          04

                          Excipient World
                          Not Confirmed
                          Excipient World
                          Not Confirmed

                          Details : A statistically significant decline in disease progression was observed during the first 3- 4 months post-treatment period, indicating a clinical benefit of the AstroRx® cell product.

                          Product Name : Undisclosed

                          Product Type : Cell and Gene therapy

                          Upfront Cash : Inapplicable

                          February 01, 2020

                          Lead Product(s) : AstroRx

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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