
Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target

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Lead Product(s) : Undisclosed
Therapeutic Area : Nutrition and Weight Loss
Study Phase : Discovery Platform
Sponsor : Eli Lilly
Deal Size : $650.0 million
Deal Type : Collaboration
Eli Lilly inks $650M Juvena pact to find muscle-boosting drugs
Details : SRF388 is a fully human anti-IL-27 antibody designed to inhibit the activity of this immunosuppressive cytokine. Surface has initiated a single-arm Phase 2 study evaluating SRF388 in combination with pembrolizumab in patients with NSCLC.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Undisclosed
June 11, 2025
Lead Product(s) : Undisclosed
Therapeutic Area : Nutrition and Weight Loss
Highest Development Status : Discovery Platform
Sponsor : Eli Lilly
Deal Size : $650.0 million
Deal Type : Collaboration

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Lead Product(s) : Undisclosed
Therapeutic Area : Musculoskeletal
Study Phase : Discovery Platform
Sponsor : Eli Lilly
Deal Size : $650.0 million
Deal Type : Collaboration
Eli Lilly Works Out $650M Juvena Pact to Find Muscle-Boosting Drugs
Details : The collaboration aims to discover, develop, and commercialize drug candidates that improve muscle health and body composition.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Undisclosed
June 11, 2025
Lead Product(s) : Undisclosed
Therapeutic Area : Musculoskeletal
Highest Development Status : Discovery Platform
Sponsor : Eli Lilly
Deal Size : $650.0 million
Deal Type : Collaboration

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Lead Product(s) : JUV-161
Therapeutic Area : Genetic Disease
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Juvena Therapeutics Announces Initiation of First-in-Human Clinical Trial of JUV-161
Details : JUV-161 is a muscle regenerating endocrine therapy being investigated for the treatment of Myotonic Dystrophy Type 1 (DM1) and Sarcopenia
Product Name : Undisclosed
Product Type : Protein
Upfront Cash : Inapplicable
May 19, 2025
Lead Product(s) : JUV-161
Therapeutic Area : Genetic Disease
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : JUV-161
Therapeutic Area : Undisclosed
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
First-In-Human Study to Evaluate Single Ascending Doses of JUV-161 in Healthy Adult Volunteers
Details : JUV-161 is a Protein drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of undefined medical condition.
Product Name : Undisclosed
Product Type : Protein
Upfront Cash : Inapplicable
April 09, 2025
Lead Product(s) : JUV-161
Therapeutic Area : Undisclosed
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : JUV-161
Therapeutic Area : Genetic Disease
Study Phase : IND Enabling
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Juvena Receives FDA Orphan Drug Designation for JUV-161 in Myotonic Dystrophy
Details : JUV-161, identified via Juvena’s AI platform, restores muscle fiber formation, counters muscle atrophy, and enhances strength, currently in preclinical studies for DM1.
Product Name : Undisclosed
Product Type : Protein
Upfront Cash : Inapplicable
January 23, 2024
Lead Product(s) : JUV-161
Therapeutic Area : Genetic Disease
Highest Development Status : IND Enabling
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : JUV-161
Therapeutic Area : Genetic Disease
Study Phase : IND Enabling
Sponsor : Mubadala Capital
Deal Size : $41.0 million
Deal Type : Series A Financing
Details : JUV-161 is the only protein-based therapeutic being developed for a rare muscle-wasting disease, myotonic dystrophy type 1 (DM1).
Product Name : Undisclosed
Product Type : Protein
Upfront Cash : Undisclosed
November 08, 2022
Lead Product(s) : JUV-161
Therapeutic Area : Genetic Disease
Highest Development Status : IND Enabling
Sponsor : Mubadala Capital
Deal Size : $41.0 million
Deal Type : Series A Financing

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Lead Product(s) : JUV-161
Therapeutic Area : Genetic Disease
Study Phase : Preclinical
Sponsor : California Institute for Regenerative Medicine
Deal Size : $3.9 million
Deal Type : Funding
Details : The grant will fund the advancement of Juvena's lead program, fusion protein therapeutic JUV-161, for the treatment of the rare muscle-wasting disease, DM1, through initial IND-enabling studies and a pre-IND FDA meeting in the next 12-16 months.
Product Name : Undisclosed
Product Type : Protein
Upfront Cash : Undisclosed
February 02, 2022
Lead Product(s) : JUV-161
Therapeutic Area : Genetic Disease
Highest Development Status : Preclinical
Sponsor : California Institute for Regenerative Medicine
Deal Size : $3.9 million
Deal Type : Funding
