[{"orgOrder":0,"company":"Ivy Brain Tumor Center","sponsor":"GSK","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Other Small Molecule","year":"2024","type":"Inapplicable","leadProduct":"Niraparib Tosylate","moa":"Poly [ADP-ribose] polymerase-1 | Poly [ADP-ribose] polymerase 2","graph1":"Oncology","graph2":"Phase III","graph3":"Ivy Brain Tumor Center","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Oral","sponsorNew":"Ivy Brain Tumor Center \/ GSK","highestDevelopmentStatusID":"10","companyTruncated":"Ivy Brain Tumor Center \/ GSK"},{"orgOrder":0,"company":"Ivy Brain Tumor Center","sponsor":"BeOne Medicines","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Other Small Molecule","year":"2022","type":"Inapplicable","leadProduct":"Pamiparib","moa":"||Poly [ADP-ribose] polymerase 2 | Poly [ADP-ribose] polymerase-1","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Ivy Brain Tumor Center","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Oral Capsule","sponsorNew":"Ivy Brain Tumor Center \/ Ivy Brain Tumor Center","highestDevelopmentStatusID":"7","companyTruncated":"Ivy Brain Tumor Center \/ Ivy Brain Tumor Center"},{"orgOrder":0,"company":"Ivy Brain Tumor Center","sponsor":"BridgeBio Pharma","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Other Small Molecule","year":"2020","type":"Inapplicable","leadProduct":"Infigratinib","moa":"Fibroblast growth factor receptor","graph1":"Oncology","graph2":"Phase I","graph3":"Ivy Brain Tumor Center","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Oral Tablet","sponsorNew":"Ivy Brain Tumor Center \/ Ivy Brain Tumor Center","highestDevelopmentStatusID":"6","companyTruncated":"Ivy Brain Tumor Center \/ Ivy Brain Tumor Center"},{"orgOrder":0,"company":"Ivy Brain Tumor Center","sponsor":"GSK","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Cytotoxic Drug","year":"2021","type":"Collaboration","leadProduct":"Niraparib Tosylate","moa":"Poly [ADP-ribose] polymerase-1 | Poly [ADP-ribose] polymerase 2","graph1":"Oncology","graph2":"IND Enabling","graph3":"Ivy Brain Tumor Center","amount2":0,"highestDevelopmentShortName":"IND","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Oral Tablet","sponsorNew":"Ivy Brain Tumor Center \/ GSK","highestDevelopmentStatusID":"5","companyTruncated":"Ivy Brain Tumor Center \/ GSK"},{"orgOrder":0,"company":"Ivy Brain Tumor Center","sponsor":"Vivace Therapeutics","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Other Small Molecule","year":"2020","type":"Collaboration","leadProduct":"VT-01","moa":"TEAD palmitoylation","graph1":"Oncology","graph2":"Preclinical","graph3":"Ivy Brain Tumor Center","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Ivy Brain Tumor Center \/ Ivy Brain Tumor Center","highestDevelopmentStatusID":"4","companyTruncated":"Ivy Brain Tumor Center \/ Ivy Brain Tumor Center"}]

Find Clinical Drug Pipeline Developments & Deals by Ivy Brain Tumor Center

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                          Top Deals by Deal Size (USD bn)

                          01

                          iPHEX India
                          Not Confirmed
                          iPHEX India
                          Not Confirmed

                          Details : Undisclosed

                          Product Name : Undisclosed

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          April 29, 2024

                          Lead Product(s) : Niraparib Tosylate

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : GSK

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          02

                          iPHEX India
                          Not Confirmed
                          iPHEX India
                          Not Confirmed

                          Details : The interim analysis demonstrated that pamiparib is well-tolerated in glioblastoma patients, reaches pharmacologically-relevant concentrations in nonenhancing GBM tissue, and sensitizes brain tumor tissue to radiation ex vivo.

                          Product Name : Undisclosed

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          October 09, 2022

                          Lead Product(s) : Pamiparib,Temozolomide

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Recipient : BeOne Medicines

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          03

                          iPHEX India
                          Not Confirmed
                          iPHEX India
                          Not Confirmed

                          Details : The launch of the Phase 0 clinical trial with niraparib will begin by enrolling six Arm A participants to determine the Optimal Time Interval (OTI) and the tumor resection that can detect maximum unbound drug concentration in the gadolinium nonenhancing ...

                          Product Name : Zejula

                          Product Type : Cytotoxic Drug

                          Upfront Cash : Undisclosed

                          October 22, 2021

                          Lead Product(s) : Niraparib Tosylate

                          Therapeutic Area : Oncology

                          Highest Development Status : IND Enabling

                          Sponsor : GSK

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

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                          04

                          iPHEX India
                          Not Confirmed
                          iPHEX India
                          Not Confirmed

                          Details : The Ivy Brain Tumor Center, which employs a bold, early-phase clinical trials strategy, will evaluate Vivace’s novel development compound, VT-01, as an experimental therapy in two aggressive forms of brain cancer – glioblastoma and meningioma.

                          Product Name : Undisclosed

                          Product Type : Other Small Molecule

                          Upfront Cash : Undisclosed

                          August 26, 2020

                          Lead Product(s) : VT-01

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Recipient : Vivace Therapeutics

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

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                          05

                          iPHEX India
                          Not Confirmed
                          iPHEX India
                          Not Confirmed

                          Details : Precision medicine study designed to confirm infigratinib's ability to cross blood-brain barrier and hit molecular targets in high-grade glioma patients with FGFR genetic alterations.

                          Product Name : Truseltiq

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          July 28, 2020

                          Lead Product(s) : Infigratinib

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Recipient : BridgeBio Pharma

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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