Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Cannabidiol,Isoflurane
Therapeutic Area : Trauma (Emergency, Injury, Surgery)
Study Phase : Preclinical
Sponsor : Incannex Healthcare
Deal Size : Undisclosed
Deal Type : Agreement
Details : Under the terms of the agreement, Vectura will undertake formulation screening studies, manufacturing process optimisation studies and stability assessments, as well as manufacturing a laboratory-scale batch of IHL-216A (Cannabidiol) to support toxicolog...
Product Name : Undisclosed
Product Type : Controlled Substance
Upfront Cash : Undisclosed
June 22, 2021
Lead Product(s) : Cannabidiol,Isoflurane
Therapeutic Area : Trauma (Emergency, Injury, Surgery)
Highest Development Status : Preclinical
Sponsor : Incannex Healthcare
Deal Size : Undisclosed
Deal Type : Agreement
Lead Product(s) : Isoflurane
Therapeutic Area : Neurology
Study Phase : Phase III
Sponsor : Critical Illness, Brain Dysfunction, and Survivorship Center
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Isoflurane is a Other Small Molecule drug candidate, which is currently being evaluated in phase III clinical studies for the treatment of postintensive care syndrome.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
February 05, 2025
Lead Product(s) : Isoflurane
Therapeutic Area : Neurology
Highest Development Status : Phase III
Sponsor : Critical Illness, Brain Dysfunction, and Survivorship Center
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Isoflurane
Therapeutic Area : Neurology
Study Phase : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Sedana Medical Completes Patient Recruitment for INSPiRE-ICU 1 Clinical Trial in the US
Details : Sedaconda (isoflurane) is an inhalation anesthetic that acts as a GABAA receptor modulator, decreasing motor function and inhibiting excitatory neurotransmission via NMDA receptors.
Product Name : Sedaconda
Product Type : Miscellaneous
Upfront Cash : Inapplicable
April 25, 2024
Lead Product(s) : Isoflurane
Therapeutic Area : Neurology
Highest Development Status : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Isoflurane
Therapeutic Area : Undisclosed
Study Phase : Phase III
Sponsor : Canadian Institutes of Health Research
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Isoflurane is a Other Small Molecule drug candidate, which is currently being evaluated in phase III clinical studies for the treatment of Mechanically Ventilated Children.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
May 22, 2023
Lead Product(s) : Isoflurane
Therapeutic Area : Undisclosed
Highest Development Status : Phase III
Sponsor : Canadian Institutes of Health Research
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Isoflurane
Therapeutic Area : Neurology
Study Phase : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Sedana Medical Receives FDA Fast Track Designation in The United States
Details : Sedaconda (isoflurane), a general inhalation anesthetic, acts as a positive allosteric GABAA receptor modulator. It enhances glycine receptor activity, which decreases motor function and inhibits NMDA glutamate receptor, which mediates excitatory neurotr...
Product Name : Sedaconda
Product Type : Miscellaneous
Upfront Cash : Inapplicable
January 04, 2023
Lead Product(s) : Isoflurane
Therapeutic Area : Neurology
Highest Development Status : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Cannabidiol,Isoflurane
Therapeutic Area : Trauma (Emergency, Injury, Surgery)
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : IHL-216A (cannabidiol) is a CB1 receptor negative allosteric modulator. It is being evaluated in preclinical studies in combination with Isoflurane for the treatment of traumatic brain injury & concussion.
Product Name : Undisclosed
Product Type : Controlled Substance
Upfront Cash : Inapplicable
October 11, 2022
Lead Product(s) : Cannabidiol,Isoflurane
Therapeutic Area : Trauma (Emergency, Injury, Surgery)
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Cannabidiol,Isoflurane
Therapeutic Area : Trauma (Emergency, Injury, Surgery)
Study Phase : Preclinical
Sponsor : Curia
Deal Size : Undisclosed
Deal Type : Agreement
Incannex Engages Curia to Scale-up Manufacture of cGMP IHL-216A
Details : IHL-216A (cannabidiol) has been observed to have a greater neuroprotective effect in a rodent model of sports concussion than CBD, and results indicate restoration of the spatial memory deficit post-concussion with IHL-216A administration.
Product Name : Undisclosed
Product Type : Controlled Substance
Upfront Cash : Undisclosed
August 02, 2022
Lead Product(s) : Cannabidiol,Isoflurane
Therapeutic Area : Trauma (Emergency, Injury, Surgery)
Highest Development Status : Preclinical
Sponsor : Curia
Deal Size : Undisclosed
Deal Type : Agreement
Lead Product(s) : Isoflurane
Therapeutic Area : Undisclosed
Study Phase : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Isoflurane is a Other Small Molecule drug candidate, which is currently being evaluated in phase III clinical studies for the treatment of undefined medical condition.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
April 14, 2022
Lead Product(s) : Isoflurane
Therapeutic Area : Undisclosed
Highest Development Status : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Isoflurane
Therapeutic Area : Undisclosed
Study Phase : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Isoflurane is a Other Small Molecule drug candidate, which is currently being evaluated in phase III clinical studies for the treatment of undefined medical condition.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
April 05, 2022
Lead Product(s) : Isoflurane
Therapeutic Area : Undisclosed
Highest Development Status : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Isoflurane
Therapeutic Area : Neurology
Study Phase : Approved FDF
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Sedana Medical receives IND approval for US trials
Details : Company received IND clearance from the USFDA to initiate phase III pivotal clinical trials with its combination registration of medical device Sedaconda ACD and pharmaceutical Sedaconda (isoflurane) for sedation of mechanically ventilated intensive care...
Product Name : Sedaconda
Product Type : Miscellaneous
Upfront Cash : Inapplicable
December 23, 2021
Lead Product(s) : Isoflurane
Therapeutic Area : Neurology
Highest Development Status : Approved FDF
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable