
Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target

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Lead Product(s) : IO102-IO103,IO103,Pembrolizumab
Therapeutic Area : Oncology
Study Phase : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
IO Biotech Completes Phase 2 Enrollment for IO102-IO103 Cancer Vaccine
Details : IO102-IO103 is an off-the-shelf, cancer vaccine, kills both tumor cells and immune-suppressive cells. It is being evaluated for resectable melanoma or head and neck cancer.
Product Name : Undisclosed
Product Type : Peptide, Unconjugated
Upfront Cash : Inapplicable
January 09, 2025
Lead Product(s) : IO102-IO103,IO103,Pembrolizumab
Therapeutic Area : Oncology
Highest Development Status : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : IO102-IO103,IO103,Pembrolizumab
Therapeutic Area : Oncology
Study Phase : Phase III
Sponsor : EIB
Deal Size : Undisclosed
Deal Type : Financing
IO Biotech Secures Up to €57.5 million in Debt Financing from The European Investment Bank
Details : The financing aims to advance the clinical development of the company's lead product IO102-IO103 an immune-modulatory, off-the-shelf therapeutic cancer vaccine for resectable melanoma.
Product Name : Undisclosed
Product Type : Peptide, Unconjugated
Upfront Cash : Undisclosed
December 20, 2024
Lead Product(s) : IO102-IO103,IO103,Pembrolizumab
Therapeutic Area : Oncology
Highest Development Status : Phase III
Sponsor : EIB
Deal Size : Undisclosed
Deal Type : Financing

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Lead Product(s) : IO102-IO103,IO103,Pembrolizumab
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Merck & Co
Deal Size : Inapplicable
Deal Type : Inapplicable
IO Biotech IO102-IO103 with KEYTRUDA® Shows Promising Cancer Vaccine Results
Details : IO102-IO103 is an off-the-shelf, cancer vaccine, kills both tumor cells and immune-suppressive cells. It is being evaluated in combination with keytruda for metastatic non-small cell lung cancer.
Product Name : Undisclosed
Product Type : Peptide, Unconjugated
Upfront Cash : Inapplicable
November 07, 2024
Lead Product(s) : IO102-IO103,IO103,Pembrolizumab
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Merck & Co
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : IO102-IO103,IO103,Pembrolizumab
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
IO Biotech Reports Positive Results from Ph 2 Trial of IO102-IO103 in Head and Neck Cancer
Details : IO102-IO103 is an off-the-shelf, cancer vaccine designed to kill both tumor cells and immune-suppressive cells. It is being evaluated for squamous cell carcinoma of the head and neck.
Product Name : Undisclosed
Product Type : Peptide, Unconjugated
Upfront Cash : Inapplicable
September 14, 2024
Lead Product(s) : IO102-IO103,IO103,Pembrolizumab
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : IO102-IO103,IO103,Pembrolizumab
Therapeutic Area : Oncology
Study Phase : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
IO Biotech Updates on Phase 3 IO102-IO103 Trial with KEYTRUDA® in Melanoma
Details : IO102-IO103 is an cancer vaccine designed to kill both tumor cells and immune-suppressive cells. It is being investigated in combination with pembrolizumab for the treatment of resectable melanoma.
Product Name : Undisclosed
Product Type : Peptide, Unconjugated
Upfront Cash : Inapplicable
August 30, 2024
Lead Product(s) : IO102-IO103,IO103,Pembrolizumab
Therapeutic Area : Oncology
Highest Development Status : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : IRX4204
Therapeutic Area : Neurology
Study Phase : Preclinical
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Io Therapeutics Presents IRX4204 Results for ALS Treatment
Details : IRX4204 is the company’s phase II clinical development stage, highly selective RXR nuclear receptor agonist compound, supporting its potential use for treatment of amyotrophic lateral sclerosis (ALS).
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
July 16, 2024
Lead Product(s) : IRX4204
Therapeutic Area : Neurology
Highest Development Status : Preclinical
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

Io Therapeutics Presents IRX4204 Data for Aging, Parkinson’s, and Alzheimer’s
Details : IRX4204 is a highly potent and highly selective, orally available, third generation RXR agonist compound which IS being tested in early phase clinical trials in patients with Parkinson’s disease
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
July 09, 2024

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Lead Product(s) : IO102-IO103,IO103,Pembrolizumab
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
IO Biotech Announces First Patient Dosed in Phase 2 Neoadjuvant/Adjuvant Solid Tumor Basket Trial
Details : IO102-IO103 is an off-the-shelf, cancer vaccine designed to kill both tumor cells and immune-suppressive cells. It is under phase 2 clinial trials in combination with pembrolizumab for the treatment of resectable melanoma or squamous cell carcinoma of th...
Product Name : Undisclosed
Product Type : Peptide, Unconjugated
Upfront Cash : Inapplicable
December 21, 2023
Lead Product(s) : IO102-IO103,IO103,Pembrolizumab
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : IO102-IO103,IO103,Pembrolizumab
Therapeutic Area : Oncology
Study Phase : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
IO Biotech Completes Enrollment of 380 Patients in Pivotal Phase 3 Trial in Advanced Melanoma
Details : IO102-IO103 is an investigational immune-modulating cancer vaccine designed to target the immunosuppressive mechanisms mediated by the proteins indoleamine 2,3-dioxygenase (IDO) and PD-L1.
Product Name : Undisclosed
Product Type : Peptide, Unconjugated
Upfront Cash : Inapplicable
November 10, 2023
Lead Product(s) : IO102-IO103,IO103,Pembrolizumab
Therapeutic Area : Oncology
Highest Development Status : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : IO102-IO103,IO103,Pembrolizumab
Therapeutic Area : Oncology
Study Phase : Phase III
Sponsor : Lundbeckfonden BioCapital
Deal Size : $75.0 million
Deal Type : Private Placement
IO Biotech, Inc. Announces $75 Million Private Placement Financing
Details : The net proceeds will be used for the development of IO102-IO103, an investigational immune-modulating cancer vaccine designed to target the immunosuppressive mechanisms mediated by the proteins indoleamine 2,3-dioxygenase (IDO) and PD-L1.
Product Name : Undisclosed
Product Type : Peptide, Unconjugated
Upfront Cash : Undisclosed
August 07, 2023
Lead Product(s) : IO102-IO103,IO103,Pembrolizumab
Therapeutic Area : Oncology
Highest Development Status : Phase III
Sponsor : Lundbeckfonden BioCapital
Deal Size : $75.0 million
Deal Type : Private Placement
