
Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target

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Lead Product(s) : INT2104
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Kite Pharma
Deal Size : $350.0 million
Deal Type : Acquisition
Kite to Acquire Interius Biotherapeutics to Advance in Vivo Platform
Details : Kite will enhance its expertise in cell therapy by incorporating Interius’s integrating in vivo platform & also leverage pipeline, including INT2104, being evaluated for B cell malignancies.
Product Name : INT2104
Product Type : Cell & Gene Therapy
Upfront Cash : $350.0 million
August 21, 2025
Lead Product(s) : INT2104
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Kite Pharma
Deal Size : $350.0 million
Deal Type : Acquisition

Interius BioTherapeutics Announces Phase 1 Trial Expansion Approval in Europe
Details : INT2104 is a first-in-class gene therapy that delivers a CAR transgene to generate effector CAR-T and CAR-NK cells. It is being evaluated for the treatment of refractory/relapsing b-cell malignancies.
Product Name : Undisclosed
Product Type : Cell & Gene Therapy
Upfront Cash : Inapplicable
January 07, 2025

Interius Doses First Patient with in Vivo CAR Therapy for B-Cell Malignancies
Details : INT2104, is an off the shelf, investigational, IV gene therapy, targeting CD7-positive T & NK cells & delivers a CAR transgene to create effector CAR-T & CAR-NK cells for r/r B-cell malignancies.
Product Name : Undisclosed
Product Type : Cell & Gene Therapy
Upfront Cash : Inapplicable
October 23, 2024

Details : INT2104 is a Cell and Gene Therapy drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Lymphoma, B-Cell.
Product Name : Undisclosed
Product Type : Cell & Gene Therapy
Upfront Cash : Inapplicable
August 06, 2024

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Lead Product(s) : INT2104
Therapeutic Area : Oncology
Study Phase : IND Enabling
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Interius BioTherapeutics Receives HREC Approval for Phase 1 CAR Therapeutic Trial
Details : INT2104, is an off the shelf, investigational, IV gene therapy, targeting CD7-positive T & NK cells & delivers a CAR transgene to create effector CAR-T & CAR-NK cells for r/r B-cell malignancies.
Product Name : Undisclosed
Product Type : Cell & Gene Therapy
Upfront Cash : Inapplicable
July 09, 2024
Lead Product(s) : INT2104
Therapeutic Area : Oncology
Highest Development Status : IND Enabling
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : INT2104
Therapeutic Area : Oncology
Study Phase : Preclinical
Recipient : WuXi Advanced Therapies
Deal Size : Undisclosed
Deal Type : Partnership
Interius BioTherapeutics Announces Successful Manufacturing Partnership with WuXi Advanced Therapies
Details : Through the partnership, Interius will leverage WuXi ATU's CTDMO platform for Good Manufacturing Process (GMP) manufacturing of Phase I clinical product and will advance INT-2104 in vivo CART program for B cell malignancies to the clinic.
Product Name : Undisclosed
Product Type : Cell & Gene Therapy
Upfront Cash : Undisclosed
May 08, 2023
Lead Product(s) : INT2104
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Recipient : WuXi Advanced Therapies
Deal Size : Undisclosed
Deal Type : Partnership
