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            Lead Product(s): Lefamulin Acetate

            Therapeutic Area: Infections and Infectious Diseases Product Name: Xenleta

            Highest Development Status: Approved Product Type: Small molecule

            Partner/Sponsor/Collaborator: Nabriva Therapeutics

            Deal Size: $101.0 million Upfront Cash: $5.0 million

            Deal Type: Licensing Agreement December 07, 2020

            Details:

            The restructured agreement provides for additional manufacturing collaboration and regulatory support [to be provided to Sinovant by Nabriva] that is expected to help expedite the delivery of XENLETA to patients in greater China.

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            Lead Product(s): Lefamulin Acetate

            Therapeutic Area: Infections and Infectious Diseases Product Name: Xenleta

            Highest Development Status: Approved Product Type: Small molecule

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable October 13, 2020

            Details:

            Findings underscore potential of XENLETA as a first-in-class pleuromutilin antibiotic for the IV and oral treatment of CABP in adults, including older patients with comorbidities who are at risk of poor outcomes

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            Lead Product(s): Lefamulin Acetate

            Therapeutic Area: Infections and Infectious Diseases Product Name: Xenleta

            Highest Development Status: Approved Product Type: Small molecule

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable July 23, 2020

            Details:

            In pre-clinical model, lefamulin shows anti-inflammatory activity comparable to dexamethasone.

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            Lead Product(s): Lefamulin Acetate

            Therapeutic Area: Infections and Infectious Diseases Product Name: Xenleta

            Highest Development Status: Approved Product Type: Small molecule

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable July 16, 2020

            Details:

            Nabriva Therapeutics has received approval from Health Canada to market oral and intravenous (IV) formulations of XENLETA® (lefamulin) for the treatment of community-acquired pneumonia (CAP) in adults.