Athena Athena

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molecule","productStatus":"New Molecular Entity","date":"December 2023","url1":"","url2":"","graph1":"Technology","graph2":"Discovery Platform"},{"orgOrder":0,"company":"ImmunoPrecise","sponsor":"The Benchmark Company","pharmaFlowCategory":"D","amount":"$1.2 million","upfrontCash":"Undisclosed","newsHeadline":"IPA Announces Closing of $1.265 Million Public Offering of Common Shares","therapeuticArea":"Technology","highestDevelopmentStatus":"Discovery","country":"U.S.A","productType":"Large molecule","productStatus":"New Molecular Entity","date":"December 2023","url1":"","url2":"","graph1":"Technology","graph2":"Discovery"},{"orgOrder":0,"company":"ImmunoPrecise","sponsor":"The Benchmark Company","pharmaFlowCategory":"D","amount":"$1.1 million","upfrontCash":"Undisclosed","newsHeadline":"IPA Announces Pricing of $1.1 Million Public Offering of Common Shares","therapeuticArea":"Technology","highestDevelopmentStatus":"Discovery","country":"U.S.A","productType":"Large 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            Development Status

            Details:

            The Company intends to use the net proceeds from the proposed offering for research and development of its aproprietary LENS integrated intelligence technology for powerful antibody discovery.

            Lead Product(s): Undisclosed

            Therapeutic Area: Technology Product Name: Undisclosed

            Highest Development Status: Discovery Product Type: Large molecule

            Partner/Sponsor/Collaborator: The Benchmark Company

            Deal Size: $1.2 million Upfront Cash: Undisclosed

            Deal Type: Public Offering December 08, 2023

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            The Company intends to use the net proceeds from the proposed offering for research and development of its aproprietary LENS integrated intelligence technology for powerful antibody discovery.

            Lead Product(s): Undisclosed

            Therapeutic Area: Technology Product Name: Undisclosed

            Highest Development Status: Discovery Product Type: Large molecule

            Partner/Sponsor/Collaborator: The Benchmark Company

            Deal Size: $1.1 million Upfront Cash: Undisclosed

            Deal Type: Public Offering December 06, 2023

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            The net proceeds from the proposed offering for research and development, including its optimize proprietary LENS Integrated Intelligence Technology in silico generated antibodies.

            Lead Product(s): Undisclosed

            Therapeutic Area: Technology Product Name: Undisclosed

            Highest Development Status: Discovery Platform Product Type: Large molecule

            Partner/Sponsor/Collaborator: The Benchmark Company LLC

            Deal Size: Undisclosed Upfront Cash: Undisclosed

            Deal Type: Public Offering December 05, 2023

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            The companies will jointly conduct research activities to identify and optimize proprietary LENS Integrated Intelligence Technology in silico generated antibodies, targeting an undisclosed target in the TME, as potential therapeutic development candidates.

            Lead Product(s): Antibody

            Therapeutic Area: Oncology Product Name: Undisclosed

            Highest Development Status: Discovery Product Type: Large molecule

            Partner/Sponsor/Collaborator: Xyphos Biosciences

            Deal Size: Undisclosed Upfront Cash: Undisclosed

            Deal Type: Collaboration March 30, 2023

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            Talem and Libera Bio will jointly develop novel antibodies for use with MPN delivery. The program will leverage BioStrand’s LENSai® Full Suite of Integrated Intelligence Technology® with Libera Bio’s Multifunctional Polymeric Nanocapsules (MPN Technology®).

            Lead Product(s): Antibody

            Therapeutic Area: Oncology Product Name: Undisclosed

            Highest Development Status: Discovery Product Type: Large molecule

            Recipient: Libera Bio

            Deal Size: $155.0 million Upfront Cash: Undisclosed

            Deal Type: Collaboration March 15, 2023

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            Details:

            Under the terms of the agreement, Talem will oversee the development and optimization of the antibodies for each program. OmniAb and Talem will share downstream economics upon potential out-licensing or commercialization of the OmniChicken-derived antibody.

            Lead Product(s): OmniChicken-derived Antibody

            Therapeutic Area: Oncology Product Name: Undisclosed

            Highest Development Status: Discovery Platform Product Type: Large molecule

            Partner/Sponsor/Collaborator: OmniAb

            Deal Size: Undisclosed Upfront Cash: Undisclosed

            Deal Type: Licensing Agreement October 12, 2022

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            Details:

            The blinded studies examined the efficacy of IPA’s PolyTope® TATX-03 antibody combination therapy alongside in-house derived formulations of several commercially approved antibodies.

            Lead Product(s): TATX-03

            Therapeutic Area: Infections and Infectious Diseases Product Name: PolyTope TATX-03

            Highest Development Status: IND Enabling Product Type: Large molecule

            Partner/Sponsor/Collaborator: Ludwig-Maximilians-University

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable August 29, 2022

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            Details:

            IND-enabling safety evaluations of PolyTope® TATX-03, executed under GLP standards and regulatory guidelines, revealed no in vivo adverse effects during histopathological examination nor any undesirable off-target binding to human biomaterials.

            Lead Product(s): TATX-03

            Therapeutic Area: Infections and Infectious Diseases Product Name: PolyTope TATX-03

            Highest Development Status: IND Enabling Product Type: Large molecule

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable July 12, 2022

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            Details:

            IPA's PolyTope® TATX-03 shows continuous validation of potent in vitro neutralizing activity against SARS-CoV-2 variants of concern, as further demonstrated against the Omicron sublineage BA.2.

            Lead Product(s): TATX-03

            Therapeutic Area: Infections and Infectious Diseases Product Name: PolyTope TATX-03

            Highest Development Status: IND Enabling Product Type: Large molecule

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable April 20, 2022

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            Details:

            In vivo, IND enabling evaluations of PolyTope® TATX-03, antibody cocktail therapy in the animal model showed that there were no pharmacokinetic aberrations and, injection with TATX-03 is well tolerated – with a significant safety margin and no clinical signs of toxicity.

            Lead Product(s): TATX-03

            Therapeutic Area: Infections and Infectious Diseases Product Name: PolyTope TATX-03

            Highest Development Status: IND Enabling Product Type: Large molecule

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable March 09, 2022

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