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therapy","year":"2025","type":"Partnership","leadProduct":"Undisclosed","moa":"Undisclosed","graph1":"Immunology","graph2":"Preclinical","graph3":"GeneFab","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"GeneFab \/ RegCell","highestDevelopmentStatusID":"4","companyTruncated":"GeneFab \/ RegCell"},{"orgOrder":0,"company":"AGC Biologics","sponsor":"Quell Therapeutics","pharmaFlowCategory":"D","therapeuticArea":"Immunology","country":"U.S.A","productType":"Cell and Gene therapy","year":"2025","type":"Collaboration","leadProduct":"Undisclosed","moa":"Undisclosed","graph1":"Immunology","graph2":"Preclinical","graph3":"AGC Biologics","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"AGC Biologics \/ Quell Therapeutics","highestDevelopmentStatusID":"4","companyTruncated":"AGC Biologics \/ Quell Therapeutics"}]

Find Clinical Drug Development Pipelines & Deals | PipelineProspector

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                          Therapeutic Area by Lead Product

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                          Top Deals by Deal Size (USD bn)

                          01

                          Pharmex
                          Not Confirmed
                          Pharmex
                          Not Confirmed

                          Details : The partnership will support the tech transfer and clinical manufacturing of RegCell’s Treg platform and accelerate U.S. clinical trials for autoimmune indications, including autoimmune hepatitis.

                          Product Name : Undisclosed

                          Product Type : Cell and Gene therapy

                          Upfront Cash : Undisclosed

                          May 07, 2025

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Immunology

                          Highest Development Status : Preclinical

                          Sponsor : RegCell

                          Deal Size : Undisclosed

                          Deal Type : Partnership

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                          02

                          Pharmex
                          Not Confirmed
                          Pharmex
                          Not Confirmed

                          Details : Novelty Nobility will leverage AGC Biologics’ expertise and proprietary CHEF1® expression technology for cell line development and prepare for Phase I clinical trials

                          Product Name : Undisclosed

                          Product Type : Antibody-drug Conjugate

                          Upfront Cash : Undisclosed

                          May 05, 2025

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Immunology

                          Highest Development Status : Preclinical

                          Sponsor : Novelty Nobility

                          Deal Size : Undisclosed

                          Deal Type : Partnership

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                          03

                          Pharmex
                          Not Confirmed
                          Pharmex
                          Not Confirmed

                          Details : COYA 303 is an investigational biologic combination of COYA 301, low-dose interleukin 2 and a GLP-1RA, designed to treat autoimmune and neurodegenerative diseases.

                          Product Name : COYA 303

                          Product Type : Protein

                          Upfront Cash : Inapplicable

                          April 21, 2025

                          Lead Product(s) : COYA 301,Undisclosed

                          Therapeutic Area : Immunology

                          Highest Development Status : Preclinical

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          04

                          Pharmex
                          Not Confirmed
                          Pharmex
                          Not Confirmed

                          Details : The collaboration aims to accelerate the development of CUE-501, a bispecific designed to direct selective memory T cells to target and deplete B cells. It is being evaluated for autoimmune disease.

                          Product Name : CUE-501

                          Product Type : Antibody

                          Upfront Cash : $12.0 million

                          April 14, 2025

                          Lead Product(s) : CUE-501

                          Therapeutic Area : Immunology

                          Highest Development Status : Preclinical

                          Sponsor : Boehringer Ingelheim GmbH

                          Deal Size : $357.0 million

                          Deal Type : Collaboration

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                          05

                          Pharmex
                          Not Confirmed
                          Pharmex
                          Not Confirmed

                          Details : The proceeds from the financing will be used to advance RayThera’s lead drug candidates through Phase 1 clinical studies.

                          Product Name : Undisclosed

                          Product Type : Other Small Molecule

                          Upfront Cash : Undisclosed

                          April 04, 2025

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Immunology

                          Highest Development Status : Preclinical

                          Sponsor : Foresite Capital

                          Deal Size : $110.0 million

                          Deal Type : Series A Financing

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                          06

                          Pharmex
                          Not Confirmed
                          Pharmex
                          Not Confirmed

                          Details : The collaboration will leverage Kenox extensive expertise in nasal and inhaled pharmaceutical development of LCTG-001. It is being evaluated for mucosal-targeted Secretory IgA.

                          Product Name : LCTG-001

                          Product Type : Antibody

                          Upfront Cash : Undisclosed

                          March 10, 2025

                          Lead Product(s) : LCTG-001

                          Therapeutic Area : Immunology

                          Highest Development Status : Preclinical

                          Sponsor : Lactiga

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

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                          07

                          Pharmex
                          Not Confirmed
                          Pharmex
                          Not Confirmed

                          Details : The financing from the proceeds will support the development of Nasdepi (epinephrine). It is being evaluated for the treatment of Anaphylactic reactions due to severe allergies.

                          Product Name : Nasdepi

                          Product Type : Hormone

                          Upfront Cash : Undisclosed

                          January 22, 2025

                          Lead Product(s) : Epinephrine

                          Therapeutic Area : Immunology

                          Highest Development Status : Preclinical

                          Sponsor : Undisclosed

                          Deal Size : $11.0 million

                          Deal Type : Financing

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                          08

                          Pharmex
                          Not Confirmed
                          Pharmex
                          Not Confirmed

                          Lead Product(s) : COYA 301,Glucagon-Like-Peptide-1 Receptor Agonist

                          Therapeutic Area : Immunology

                          Study Phase : Preclinical

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : COYA 303 is an investigational biologic combination of COYA 301 and a glucagon-like-peptide-1 receptor agonist designed for subcutaneous administration, for the treatment of inflammatory diseases.

                          Product Name : COYA 303

                          Product Type : Protein

                          Upfront Cash : Inapplicable

                          January 21, 2025

                          Lead Product(s) : COYA 301,Glucagon-Like-Peptide-1 Receptor Agonist

                          Therapeutic Area : Immunology

                          Highest Development Status : Preclinical

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          09

                          Pharmex
                          Not Confirmed
                          Pharmex
                          Not Confirmed

                          Details : The proceeds will support the Company in advancing its lead product candidate, HB2198, into a clinical trial in patients living with Systemic Lupus Erythematosus.

                          Product Name : HB2198

                          Product Type : Antibody

                          Upfront Cash : Undisclosed

                          January 15, 2025

                          Lead Product(s) : HB2198

                          Therapeutic Area : Immunology

                          Highest Development Status : Preclinical

                          Sponsor : Ridgeback Capital

                          Deal Size : $30.0 million

                          Deal Type : Series A Financing

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                          10

                          Pharmex
                          Not Confirmed
                          Pharmex
                          Not Confirmed

                          Details : Through the acquisition, Veralox expands its pipeline by including preclinical cyclic AMP-GMP (cGAS) inhibitor compounds.

                          Product Name : Undisclosed

                          Product Type : Other Small Molecule

                          Upfront Cash : Undisclosed

                          January 09, 2025

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Immunology

                          Highest Development Status : Preclinical

                          Sponsor : Veralox Therapeutics

                          Deal Size : Undisclosed

                          Deal Type : Acquisition

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