Lead Product(s) : Dapirolizumab Pegol
Therapeutic Area : Immunology
Study Phase : Phase III
Sponsor : Biogen
Deal Size : Inapplicable
Deal Type : Inapplicable
UCB and Biogen Announce Positive Phase 3 Results for Dapirolizumab Pegol in Lupus
Details : CDP7657 (dapirolizumab pegol), a novel Fc-free anti-CD40L drug candidate, investigated in people living with moderate-to-severe systemic lupus erythematosus (SLE).
Product Name : CDP7657
Product Type : Antibody
Upfront Cash : Inapplicable
September 24, 2024
Lead Product(s) : Dapirolizumab Pegol
Therapeutic Area : Immunology
Highest Development Status : Phase III
Sponsor : Biogen
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Zilucoplan Sodium
Therapeutic Area : Immunology
Study Phase : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : RA101495 (zilucoplan) is a once-daily SC, self-administered peptide inhibitor of complement component 5, which is investigated for the treatment of adults with generalized myasthenia gravis.
Product Name : Zilbrysq
Product Type : Peptide
Upfront Cash : Inapplicable
September 15, 2023
Lead Product(s) : Zilucoplan Sodium
Therapeutic Area : Immunology
Highest Development Status : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Filgotinib
Therapeutic Area : Immunology
Study Phase : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Galapagos Announces Topline Results From Phase 3 DIVERSITY Trial of Filgotinib In Crohn’s Disease
Details : Jyseleca (filgotinib) inhibits the action of Janus kinase enzymes, which are involved in the inflammation that causes the symptoms of rheumatoid arthritis and some other conditions.
Product Name : Jyseleca
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
August 02, 2023
Lead Product(s) : Filgotinib
Therapeutic Area : Immunology
Highest Development Status : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Rozanolixizumab
Therapeutic Area : Immunology
Study Phase : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : UCB7665 (Rozanolixizumab) is a subcutaneous monoclonal antibody targeting the neonatal Fc receptor (FcRn) for the treatment of adults with generalized myasthenia gravis who are antiacetycholine receptor or anti-muscle-specific tyrosine kinase antibody po...
Product Name : Rystiggo
Product Type : Antibody
Upfront Cash : Inapplicable
June 01, 2023
Lead Product(s) : Rozanolixizumab
Therapeutic Area : Immunology
Highest Development Status : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Bimekizumab
Therapeutic Area : Immunology
Study Phase : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Bimzelx (bimekizumab) is a humanized monoclonal IgG1 antibody that is designed to selectively inhibit both IL-17A and IL-17F, two key cytokines driving inflammatory processes, received positive CHMP opinion for psoriatic arthritis and axial spondyloarthr...
Product Name : Bimzelx
Product Type : Antibody
Upfront Cash : Inapplicable
April 27, 2023
Lead Product(s) : Bimekizumab
Therapeutic Area : Immunology
Highest Development Status : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Filgotinib
Therapeutic Area : Immunology
Study Phase : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Galapagos Initiates Phase 3 Program with Filgotinib in Patients with Active Axial Spondyloarthritis
Details : Jyseleca (filgotinib) inhibits the action of Janus kinase enzymes, which are involved in the inflammation that causes the symptoms of active axial spondyloarthritis and some other conditions.
Product Name : Jyseleca
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
April 26, 2023
Lead Product(s) : Filgotinib
Therapeutic Area : Immunology
Highest Development Status : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Rozanolixizumab
Therapeutic Area : Immunology
Study Phase : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : UCB7665 (rozanolixizumab) humanized mAb that specifically binds, with high affinity, to human neonatal FcRn. Designed to block the interaction of FcRn and IgG, accelerating the catabolism of antibodies and reducing the concentration of pathogenic IgG aut...
Product Name : Rystiggo
Product Type : Antibody
Upfront Cash : Inapplicable
April 13, 2023
Lead Product(s) : Rozanolixizumab
Therapeutic Area : Immunology
Highest Development Status : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Zilucoplan Sodium
Therapeutic Area : Immunology
Study Phase : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Zilucoplan is a subcutaneous (SC), self-administered peptide inhibitor of complement component 5 (C5 inhibitor) for the treatment of adult patients with acetylcholine receptor antibody positive (AChR-Ab+) generalized myasthenia gravis (gMG).
Product Name : Zilbrysq
Product Type : Peptide
Upfront Cash : Inapplicable
November 14, 2022
Lead Product(s) : Zilucoplan Sodium
Therapeutic Area : Immunology
Highest Development Status : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Arsenic Trioxide
Therapeutic Area : Immunology
Study Phase : Phase III
Sponsor : Medsenic
Deal Size : Undisclosed
Deal Type : Acquisition
Details : The acquisition of Medsenic and its specialized pipeline in the development of optimized formulations of arsenic trioxide (Arscimed) and their applications in serious inflammatory/autoimmune conditions and other potential new indications.
Product Name : Arscimed
Product Type : Cytotoxic Drug
Upfront Cash : Undisclosed
October 25, 2022
Lead Product(s) : Arsenic Trioxide
Therapeutic Area : Immunology
Highest Development Status : Phase III
Sponsor : Medsenic
Deal Size : Undisclosed
Deal Type : Acquisition
Lead Product(s) : Bimekizumab
Therapeutic Area : Immunology
Study Phase : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Bimzelx (bimekizumab) is a humanized monoclonal IgG1 antibody that is designed to selectively inhibit both interleukin 17A (IL-17A) and interleukin 17F (IL-17F), two key cytokines driving inflammatory processes.
Product Name : Bimzelx
Product Type : Antibody
Upfront Cash : Inapplicable
October 11, 2022
Lead Product(s) : Bimekizumab
Therapeutic Area : Immunology
Highest Development Status : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable