Drugs in Dev.
Immunology
Phase I
Sweden 
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Lead Product(s) : Epinephrine
Therapeutic Area : Immunology
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Orexo Announces Positive Topline Data for OX640 in Allergic Rhinitis
Details : OX640 (epinephrine) nasal powder, is a non-selective alpha and beta adrenergic agonist is being investigated for allergic reactions with and without allergic rhinitis.
Product Name : Undisclosed
Product Type : Hormone
Upfront Cash : Inapplicable
January 10, 2025
Lead Product(s) : Epinephrine
Therapeutic Area : Immunology
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Epinephrine
Therapeutic Area : Immunology
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Orexo Initiates New Study of OX640 in Participants with Allergic Rhinitis
Details : OX640 (epinephrine) is an intranasal rescue medication for severe allergic reactions with powder-based epinephrine, it is being evaluated for the treatment of allergic rhinitis.
Product Name : Undisclosed
Product Type : Hormone
Upfront Cash : Inapplicable
October 25, 2024
Lead Product(s) : Epinephrine
Therapeutic Area : Immunology
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : HNSA-5487
Therapeutic Area : Immunology
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Hansa NICE-01 Study Finds Positive Outcomes for IgG-Cleaving Molecule HNSA-5487
Details : HNSA-5487 is a company's next-generation immunoglobulin G (IgG)-cleaving molecule, assessing IgG recovery, immunogenicity, and redosing potential.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
October 07, 2024
Lead Product(s) : HNSA-5487
Therapeutic Area : Immunology
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : CAN10
Therapeutic Area : Immunology
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Cantargia Presents Data Supporting CAN10 for Systemic Sclerosis
Details : CAN10 is a Phase 1 investigational antibody that binds IL1RAP, inhibiting IL-1, IL-33, and IL-36 signaling, with potential for systemic sclerosis and myocarditis treatment.
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Inapplicable
March 14, 2024
Lead Product(s) : CAN10
Therapeutic Area : Immunology
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : AM1476
Therapeutic Area : Immunology
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
AnaMar Announces US and EU Orphan Drug Designation for AM1476 for Systemic Sclerosis
Details : AM1476 is a selective peripheral-acting 5-HT2B receptor small molecule antagonist. It is being evaluated in phase 1 clinical trials for the treatment of Systemic Sclerosis.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
February 05, 2024
Lead Product(s) : AM1476
Therapeutic Area : Immunology
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : HNSA-5487
Therapeutic Area : Immunology
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Hansa Biopharma Announces Encouraging High-Level Results for First-In-Human Trial of HNSA-5487
Details : HNSA-5487 is a next-generation IgG-cleaving enzyme, which is investigated for the treatment of IgG-driven autoimmune disease and experience flares, transplantation where repeat dosing would be beneficial, gene therapy and oncology.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
October 09, 2023
Lead Product(s) : HNSA-5487
Therapeutic Area : Immunology
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : AM1476
Therapeutic Area : Immunology
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
AnaMar Announces Positive Phase I Data for its Phase II Ready Compound AM1476 for Treating Fibrosis
Details : AM1476, as a pan anti-fibrotic medicine targeting 5-HT2B receptor and highly selective small molecule, delivered as an orally administered tablet.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
May 23, 2023
Lead Product(s) : AM1476
Therapeutic Area : Immunology
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : SOL-116
Therapeutic Area : Immunology
Study Phase : Phase I
Sponsor : QPS Holdings
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : SOL-116 is a drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Arthritis, Rheumatoid.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Inapplicable
October 12, 2022
Lead Product(s) : SOL-116
Therapeutic Area : Immunology
Highest Development Status : Phase I
Sponsor : QPS Holdings
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Epinephrine
Therapeutic Area : Immunology
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : OX640 (adrenaline) formulations showed concentration dependent effects on heart rate and blood pressure, a pharmacological response relevant for the treatment of allergic reactions.
Product Name : Undisclosed
Product Type : Hormone
Upfront Cash : Inapplicable
October 11, 2022
Lead Product(s) : Epinephrine
Therapeutic Area : Immunology
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Epinephrine
Therapeutic Area : Immunology
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
First Patent Issued in Europe for Orexo's Adrenaline Product OX640
Details : OX640 is nasal adrenaline rescue medication based on the amorphOX® drug delivery platform is a unique and innovative new product to be used for the emergency treatment of allergic reactions.
Product Name : Undisclosed
Product Type : Hormone
Upfront Cash : Inapplicable
September 01, 2022
Lead Product(s) : Epinephrine
Therapeutic Area : Immunology
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
