Lead Product(s) : Epinephrine
Therapeutic Area : Immunology
Study Phase : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Orexo Announces Positive Topline Data for OX640 in Allergic Rhinitis
Details : OX640 (epinephrine) nasal powder, is a non-selective alpha and beta adrenergic agonist is being investigated for allergic reactions with and without allergic rhinitis.
Product Name : OX640
Product Type : Hormone
Upfront Cash : Inapplicable
January 10, 2025
Lead Product(s) : Epinephrine
Therapeutic Area : Immunology
Highest Development Status : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Epinephrine
Therapeutic Area : Immunology
Study Phase : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Orexo Initiates New Study of OX640 in Participants with Allergic Rhinitis
Details : OX640 (epinephrine) is an intranasal rescue medication for severe allergic reactions with powder-based epinephrine, it is being evaluated for the treatment of allergic rhinitis.
Product Name : OX640
Product Type : Hormone
Upfront Cash : Inapplicable
October 25, 2024
Lead Product(s) : Epinephrine
Therapeutic Area : Immunology
Highest Development Status : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : HNSA-5487
Therapeutic Area : Immunology
Study Phase : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Hansa NICE-01 Study Finds Positive Outcomes for IgG-Cleaving Molecule HNSA-5487
Details : HNSA-5487 is a company's next-generation immunoglobulin G (IgG)-cleaving molecule, assessing IgG recovery, immunogenicity, and redosing potential.
Product Name : HNSA-5487
Product Type : Other Large Molecule
Upfront Cash : Inapplicable
July 10, 2024
Lead Product(s) : HNSA-5487
Therapeutic Area : Immunology
Highest Development Status : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : AM1476
Therapeutic Area : Immunology
Study Phase : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
AnaMar Announces US and EU Orphan Drug Designation for AM1476 for Systemic Sclerosis
Details : AM1476 is a selective peripheral-acting 5-HT2B receptor small molecule antagonist. It is being evaluated in phase 1 clinical trials for the treatment of Systemic Sclerosis.
Product Name : AM1476
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
May 02, 2024
Lead Product(s) : AM1476
Therapeutic Area : Immunology
Highest Development Status : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : CAN10
Therapeutic Area : Immunology
Study Phase : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Cantargia Presents Data Supporting CAN10 for Systemic Sclerosis
Details : CAN10 is a Phase 1 investigational antibody that binds IL1RAP, inhibiting IL-1, IL-33, and IL-36 signaling, with potential for systemic sclerosis and myocarditis treatment.
Product Name : CAN10
Product Type : Antibody
Upfront Cash : Inapplicable
March 14, 2024
Lead Product(s) : CAN10
Therapeutic Area : Immunology
Highest Development Status : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : HNSA-5487
Therapeutic Area : Immunology
Study Phase : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Hansa Biopharma Announces Encouraging High-Level Results for First-In-Human Trial of HNSA-5487
Details : HNSA-5487 is a next-generation IgG-cleaving enzyme, which is investigated for the treatment of IgG-driven autoimmune disease and experience flares, transplantation where repeat dosing would be beneficial, gene therapy and oncology.
Product Name : HNSA-5487
Product Type : Other Large Molecule
Upfront Cash : Inapplicable
September 10, 2023
Lead Product(s) : HNSA-5487
Therapeutic Area : Immunology
Highest Development Status : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : AM1476
Therapeutic Area : Immunology
Study Phase : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
AnaMar Announces Positive Phase I Data for its Phase II Ready Compound AM1476 for Treating Fibrosis
Details : AM1476, as a pan anti-fibrotic medicine targeting 5-HT2B receptor and highly selective small molecule, delivered as an orally administered tablet.
Product Name : AM1476
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
May 23, 2023
Lead Product(s) : AM1476
Therapeutic Area : Immunology
Highest Development Status : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Epinephrine
Therapeutic Area : Immunology
Study Phase : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : OX640 (adrenaline) formulations showed concentration dependent effects on heart rate and blood pressure, a pharmacological response relevant for the treatment of allergic reactions.
Product Name : OX640
Product Type : Hormone
Upfront Cash : Inapplicable
November 10, 2022
Lead Product(s) : Epinephrine
Therapeutic Area : Immunology
Highest Development Status : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Epinephrine
Therapeutic Area : Immunology
Study Phase : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Orexo’s Nasal Adrenaline Rescue Medication OX640 Enters Clinical Development
Details : Stability data generated so far for OX640 (adrenaline) strongly indicates the potential for an adrenaline product with significantly improved stability versus today's injection products, both in terms of allowed storage temperatures as well as shelf-life...
Product Name : OX640
Product Type : Hormone
Upfront Cash : Inapplicable
May 07, 2022
Lead Product(s) : Epinephrine
Therapeutic Area : Immunology
Highest Development Status : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Epinephrine
Therapeutic Area : Immunology
Study Phase : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
First Patent Issued in Europe for Orexo's Adrenaline Product OX640
Details : OX640 is nasal adrenaline rescue medication based on the amorphOX® drug delivery platform is a unique and innovative new product to be used for the emergency treatment of allergic reactions.
Product Name : OX640
Product Type : Hormone
Upfront Cash : Inapplicable
January 09, 2022
Lead Product(s) : Epinephrine
Therapeutic Area : Immunology
Highest Development Status : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable