Drugs in Dev.
Immunology
Phase I
Israel 
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Lead Product(s) : Undisclosed
Therapeutic Area : Immunology
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Raphael Reports Positive Cannabinoid Therapy Results for Arthritis
Details : Company’s cannabinoid-based formula is being investigated for the management of rheumatoid arthritis (RA).
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Inapplicable
January 07, 2025
Lead Product(s) : Undisclosed
Therapeutic Area : Immunology
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : UC-Mesenchymal Stem Cell
Therapeutic Area : Immunology
Study Phase : Phase I
Sponsor : Medical University of South Carolina | Galilee CBR
Deal Size : Inapplicable
Deal Type : Inapplicable
UC-MSC Cell Therapy Study for Systemic Lupus Erythematosus (SLE) Patients
Details : UC-Mesenchymal Stem Cell is a Cell and Gene Therapy drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Lupus Erythematosus, Systemic.
Product Name : Undisclosed
Product Type : Cell & Gene Therapy
Upfront Cash : Inapplicable
December 17, 2024
Lead Product(s) : UC-Mesenchymal Stem Cell
Therapeutic Area : Immunology
Highest Development Status : Phase I
Sponsor : Medical University of South Carolina | Galilee CBR
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Allocetra-OTS
Therapeutic Area : Immunology
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Enlivex Doses First Patient in Allocetra Phase 1 Psoriatic Arthritis Clinical Trial
Details : Allocetra is being developed as a universal, off-the-shelf cell therapy designed to reprogram macrophages into their homeostatic state in patients with psoriatic arthritis.
Product Name : Allocetra-OTS
Product Type : Cell & Gene Therapy
Upfront Cash : Inapplicable
November 14, 2024
Lead Product(s) : Allocetra-OTS
Therapeutic Area : Immunology
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Allocetra
Therapeutic Area : Immunology
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Evaluation of Allocetra by Intra-articular Injection for the Treatment of Psoriatic Arthritis
Details : Allocetra is a Cell and Gene Therapy drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Arthritis, Psoriatic.
Product Name : Undisclosed
Product Type : Cell & Gene Therapy
Upfront Cash : Inapplicable
July 26, 2024
Lead Product(s) : Allocetra
Therapeutic Area : Immunology
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Amilo-5MER
Therapeutic Area : Immunology
Study Phase : Phase I
Sponsor : Quotient Sciences
Deal Size : Inapplicable
Deal Type : Inapplicable
A First-in-Human Study of Single and Multiple Doses of Amilo-5MER in Healthy Subjects
Details : Amilo-5MER is a Peptide drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Inflammatory Diseases.
Product Name : Undisclosed
Product Type : Peptide, Unconjugated
Upfront Cash : Inapplicable
May 12, 2023
Lead Product(s) : Amilo-5MER
Therapeutic Area : Immunology
Highest Development Status : Phase I
Sponsor : Quotient Sciences
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Nebokitug
Therapeutic Area : Immunology
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : The findings support the role of CCL24 as a potential therapeutic target, demonstrating elevated serum levels of CCL24 in patients with dcSSc. High CCL24 serum levels were correlated with disease activity and worse prognosis as reflected.
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Inapplicable
June 02, 2022
Lead Product(s) : Nebokitug
Therapeutic Area : Immunology
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Avoplacel
Therapeutic Area : Immunology
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Results show the potential in the use of PLX-R18 for meaningful advantage over other existing and proposed treatments in post hematopoietic cell transplantation (HCT) patients. PLX-R18 reduced mortality from 29% to 18%1 and was well-tolerated with a fav...
Product Name : Undisclosed
Product Type : Cell & Gene Therapy
Upfront Cash : Inapplicable
March 23, 2022
Lead Product(s) : Avoplacel
Therapeutic Area : Immunology
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Epinephrine
Therapeutic Area : Immunology
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Bioavailability of Nasal Epinephrine
Details : Epinephrine is a Hormone drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Anaphylaxis.
Product Name : Undisclosed
Product Type : Hormone
Upfront Cash : Inapplicable
January 06, 2021
Lead Product(s) : Epinephrine
Therapeutic Area : Immunology
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : ApoGraft
Therapeutic Area : Immunology
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : The company has entered into an international consortium of companies to examine the therapeutic effects of stem cells on the reduction of pulmonary manifestations caused by COVID-19.
Product Name : Undisclosed
Product Type : Cell & Gene Therapy
Upfront Cash : Inapplicable
May 21, 2020
Lead Product(s) : ApoGraft
Therapeutic Area : Immunology
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Undisclosed
Therapeutic Area : Immunology
Study Phase : Phase I
Sponsor : Nicole Lindenblatt
Deal Size : Inapplicable
Deal Type : Inapplicable
Proof-of-concept Study of LymphMonitor 1.0 to Assess the Lymphatic Vessel Function
Details : This drug candidate is currently being evaluated in phase I clinical studies for the treatment of Lymphedema.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Inapplicable
May 19, 2020
Lead Product(s) : Undisclosed
Therapeutic Area : Immunology
Highest Development Status : Phase I
Sponsor : Nicole Lindenblatt
Deal Size : Inapplicable
Deal Type : Inapplicable
