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              Innovent Biologics

              • Development Update

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              CHINA China

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              CPhI North America Online

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              Innovent Announces that the First Phase I Clinical Study of Anti-Il-23 Monoclonal Antibody Ibi112 Has Been Administered to A Subject

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              Lead Product(s): IBI112

              Therapeutic Area: Immunology Product Name: IBI112

              Highest Development Status: Phase I Product Type: Large molecule

              Partner/Sponsor/Collaborator: Not Applicable

              Deal Size: Not Applicable Upfront Cash: Not Applicable

              Deal Type: Not Applicable September 01, 2020

              Details:

              The study CIBI112A101 is a randomized, double-blind, placebo-controlled, dose-escalation Phase I clinical trial to evaluate the safety and tolerability in addition with PK/PD of IBI112 when administered as a single subcutaneous or intravenous dose in healthy Chinese subjects.

              I-Mab Biopharma

              • Development Update

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              CHINA China

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              CPhI North America Online

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              I-Mab Begins Plonmarlimab Dosing In Rheumatoid Arthritis Trial

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              Lead Product(s): Plonmarlimab

              Therapeutic Area: Immunology Product Name: TJM2

              Highest Development Status: Phase I Product Type: Large molecule

              Partner/Sponsor/Collaborator: Not Applicable

              Deal Size: Not Applicable Upfront Cash: Not Applicable

              Deal Type: Not Applicable August 17, 2020

              Details:

              Plonmarlimab is a humanized immunoglobulin G1 (IgG1) antibody that targets the cytokine granulocyte-macrophage colony-stimulating factor (GM-CSF), which plays a critical role in autoimmune and inflammatory disease.

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