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Pharmaceuticals","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Immunology","country":"SWITZERLAND","productType":"Other Small Molecule","year":"2020","type":"Inapplicable","leadProduct":"PN-1007","moa":"IgM","graph1":"Immunology","graph2":"IND Enabling","graph3":"Polyneuron Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"IND","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Polyneuron Pharmaceuticals \/ Inapplicable","highestDevelopmentStatusID":"5","companyTruncated":"Polyneuron Pharmaceuticals \/ Inapplicable"},{"orgOrder":0,"company":"Alivexis","sponsor":"Melodia Therapeutics","pharmaFlowCategory":"D","therapeuticArea":"Immunology","country":"U.S.A","productType":"Other Small Molecule","year":"2024","type":"Licensing Agreement","leadProduct":"MDI-0151","moa":"Undisclosed","graph1":"Immunology","graph2":"IND 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Labs","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Immunology","country":"CANADA","productType":"Other Small Molecule","year":"2022","type":"Inapplicable","leadProduct":"Mescaline","moa":"5-HT 2A receptor (HTR2A)","graph1":"Immunology","graph2":"IND Enabling","graph3":"Biomind Labs","amount2":0,"highestDevelopmentShortName":"IND","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Biomind Labs \/ Inapplicable","highestDevelopmentStatusID":"5","companyTruncated":"Biomind Labs \/ Inapplicable"},{"orgOrder":0,"company":"InnoCare Pharma","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Immunology","country":"CHINA","productType":"Other Small Molecule","year":"2021","type":"Inapplicable","leadProduct":"ICP-332","moa":"TYK2","graph1":"Immunology","graph2":"IND Enabling","graph3":"InnoCare 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Inapplicable"},{"orgOrder":0,"company":"Vandria","sponsor":"Eurostars","pharmaFlowCategory":"D","therapeuticArea":"Immunology","country":"SWITZERLAND","productType":"Other Small Molecule","year":"2024","type":"Financing","leadProduct":"VNA-052","moa":"Undisclosed","graph1":"Immunology","graph2":"IND Enabling","graph3":"Vandria","amount2":0,"highestDevelopmentShortName":"IND","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Vandria \/ Eurostars","highestDevelopmentStatusID":"5","companyTruncated":"Vandria \/ Eurostars"},{"orgOrder":0,"company":"Timber Pharmaceuticals","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Immunology","country":"U.S.A","productType":"Other Small Molecule","year":"2021","type":"Inapplicable","leadProduct":"Sitaxentan","moa":"Endothelin receptor, ET-A\/ET-B","graph1":"Immunology","graph2":"IND Enabling","graph3":"Timber 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Group"},{"orgOrder":0,"company":"Equillium","sponsor":"ADAR1 Capital Management","pharmaFlowCategory":"D","therapeuticArea":"Immunology","country":"U.S.A","productType":"Other Small Molecule","year":"2025","type":"Financing","leadProduct":"EQ504","moa":"Aryl hydrocarbon receptor","graph1":"Immunology","graph2":"IND Enabling","graph3":"Equillium","amount2":0.050000000000000003,"highestDevelopmentShortName":"IND","therapeuticAreaShortName":"Immunology","amount2New":0.050000000000000003,"dosageForm":"Undisclosed","sponsorNew":"Equillium \/ ADAR1 Capital Management","highestDevelopmentStatusID":"5","companyTruncated":"Equillium \/ ADAR1 Capital Management"},{"orgOrder":0,"company":"Qihan Biotech","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Immunology","country":"CHINA","productType":"Cell and Gene therapy","year":"2025","type":"Inapplicable","leadProduct":"QT-019B","moa":"CD19|BCMA","graph1":"Immunology","graph2":"IND Enabling","graph3":"Qihan Biotech","amount2":0,"highestDevelopmentShortName":"IND","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Qihan Biotech \/ Undisclosed","highestDevelopmentStatusID":"5","companyTruncated":"Qihan Biotech \/ Undisclosed"}]

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                          01

                          Cell Therapy
                          Not Confirmed
                          Cell Therapy
                          Not Confirmed

                          Details : QT-019B is an off-the-shelf allogeneic CAR-T cell therapy targeting CD19 and BCMA for the treatment of for refractory systemic lupus erythematosus.

                          Product Name : QT-019B

                          Product Type : Cell and Gene therapy

                          Upfront Cash : Inapplicable

                          August 18, 2025

                          Lead Product(s) : QT-019B

                          Therapeutic Area : Immunology

                          Highest Development Status : IND Enabling

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          02

                          Cell Therapy
                          Not Confirmed
                          Cell Therapy
                          Not Confirmed

                          Details : Equillium intends to use the proceeds to fund the further development of EQ504, an investigational potent and selective aryl hydrocarbon receptor (AhR) modulator.

                          Product Name : EQ504

                          Product Type : Other Small Molecule

                          Upfront Cash : Undisclosed

                          August 11, 2025

                          Lead Product(s) : EQ504

                          Therapeutic Area : Immunology

                          Highest Development Status : IND Enabling

                          Sponsor : ADAR1 Capital Management

                          Deal Size : $50.0 million

                          Deal Type : Financing

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                          03

                          Cell Therapy
                          Not Confirmed
                          Cell Therapy
                          Not Confirmed

                          Details : Under the terms of the agreement, Otsuka is granted an exclusive license to develop, manufacture, and commercialize HBM7020, a BCMAxCD3 bispecific T-cell engager globally, excluding Greater China.

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : $47.0 million

                          June 22, 2025

                          Lead Product(s) : HBM7020

                          Therapeutic Area : Immunology

                          Highest Development Status : IND Enabling

                          Sponsor : Otsuka Pharmaceutical

                          Deal Size : $670.0 million

                          Deal Type : Licensing Agreement

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                          04

                          Cell Therapy
                          Not Confirmed
                          Cell Therapy
                          Not Confirmed

                          Details : Under the licensing agreement, Cullinan will holds the exclusive rights to develop and commercialize GR-1803 (velinotamig) in all disease areas globally outside of Greater China.

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : $20.0 million

                          June 05, 2025

                          Lead Product(s) : Velinotamig

                          Therapeutic Area : Immunology

                          Highest Development Status : IND Enabling

                          Sponsor : Cullinan Therapeutics

                          Deal Size : $712.0 million

                          Deal Type : Licensing Agreement

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                          05

                          Cell Therapy
                          Not Confirmed
                          Cell Therapy
                          Not Confirmed

                          Details : NTB003 is a second-generation fully human anti-IGF-1R monoclonal antibody, being investigated for thyroid eye disease.

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : Inapplicable

                          June 04, 2025

                          Lead Product(s) : NTB003

                          Therapeutic Area : Immunology

                          Highest Development Status : IND Enabling

                          Sponsor : Chia Tai Tianqing Pharmaceutical Group

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          06

                          Cell Therapy
                          Not Confirmed
                          Cell Therapy
                          Not Confirmed

                          Details : CLN-978 is a novel, differentiated and highly potent CD19xCD3 bispecific T cell engager. It is being evaluated for the treatment of Sjogren's Syndrome.

                          Product Name : Undisclosed

                          Product Type : Antibody

                          Upfront Cash : Inapplicable

                          April 29, 2025

                          Lead Product(s) : CLN-978

                          Therapeutic Area : Immunology

                          Highest Development Status : IND Enabling

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          07

                          Cell Therapy
                          Not Confirmed
                          Cell Therapy
                          Not Confirmed

                          Details : ATI-052 is an investigational, potential best-in-class anti-TSLP/IL-4R bispecific monoclonal antibody being developed to treat certain immuno-inflammatory diseases.

                          Product Name : Undisclosed

                          Product Type : Antibody

                          Upfront Cash : Inapplicable

                          April 22, 2025

                          Lead Product(s) : ATI-052

                          Therapeutic Area : Immunology

                          Highest Development Status : IND Enabling

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          08

                          Cell Therapy
                          Not Confirmed
                          Cell Therapy
                          Not Confirmed

                          Details : NX-0479 is a highly optimized, selective, oral degrader of IRAK4,being investigated in inflammation, in both rheumatology and dermatology.

                          Product Name : Undisclosed

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          April 17, 2025

                          Lead Product(s) : NX-0479

                          Therapeutic Area : Immunology

                          Highest Development Status : IND Enabling

                          Sponsor : Gilead Sciences

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          09

                          Cell Therapy
                          Not Confirmed
                          Cell Therapy
                          Not Confirmed

                          Details : CLN-978 is a novel, highly potent, half-life extended CD19xCD3 bispecific T cell engager construct. It is being evaluated for rheumatoid arthritis.

                          Product Name : Undisclosed

                          Product Type : Antibody

                          Upfront Cash : Inapplicable

                          April 16, 2025

                          Lead Product(s) : CLN-978

                          Therapeutic Area : Immunology

                          Highest Development Status : IND Enabling

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          10

                          Cell Therapy
                          Not Confirmed
                          Cell Therapy
                          Not Confirmed

                          Details : The financing aims to advance the clinical development of company's lead candidate, which is being evaluated for the treatment of Graves Disease.

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : Undisclosed

                          April 08, 2025

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Immunology

                          Highest Development Status : IND Enabling

                          Sponsor : Bain Capital Life Sciences

                          Deal Size : $121.0 million

                          Deal Type : Series A Financing

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