[{"orgOrder":0,"company":"IASO Bio","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Immunology","country":"CHINA","productType":"Cell & Gene Therapy","year":"2024","type":"Inapplicable","leadProduct":"Equecabtagene Autoleucel","moa":"BCMA","graph1":"Immunology","graph2":"IND Enabling","graph3":"IASO Bio","amount2":0,"highestDevelopmentShortName":"IND","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"Infusion","sponsorNew":"IASO Bio \/ Undisclosed","highestDevelopmentStatusID":"5","companyTruncated":"IASO Bio \/ Undisclosed"},{"orgOrder":0,"company":"IASO Bio","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Immunology","country":"CHINA","productType":"Cell & Gene Therapy","year":"2024","type":"Inapplicable","leadProduct":"Equecabtagene Autoleucel","moa":"BCMA","graph1":"Immunology","graph2":"IND Enabling","graph3":"IASO Bio","amount2":0,"highestDevelopmentShortName":"IND","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"IASO Bio \/ Undisclosed","highestDevelopmentStatusID":"5","companyTruncated":"IASO Bio \/ Undisclosed"},{"orgOrder":0,"company":"IASO Bio","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Immunology","country":"CHINA","productType":"Miscellaneous","year":"2024","type":"Inapplicable","leadProduct":"IASO-782","moa":"CD19","graph1":"Immunology","graph2":"IND Enabling","graph3":"IASO Bio","amount2":0,"highestDevelopmentShortName":"IND","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"IASO Bio \/ Undisclosed","highestDevelopmentStatusID":"5","companyTruncated":"IASO Bio \/ Undisclosed"},{"orgOrder":0,"company":"Chengdu Yousino Biotechnology","sponsor":"VectorBuilder","pharmaFlowCategory":"DU","therapeuticArea":"Immunology","country":"CHINA","productType":"Cell & Gene Therapy","year":"2025","type":"Inapplicable","leadProduct":"UC101","moa":"CD19","graph1":"Immunology","graph2":"IND Enabling","graph3":"Chengdu Yousino Biotechnology","amount2":0,"highestDevelopmentShortName":"IND","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Chengdu Yousino Biotechnology \/ VectorBuilder","highestDevelopmentStatusID":"5","companyTruncated":"Chengdu Yousino Biotechnology \/ VectorBuilder"},{"orgOrder":0,"company":"Qihan Biotech","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Immunology","country":"CHINA","productType":"Cell & Gene Therapy","year":"2025","type":"Inapplicable","leadProduct":"QT-019B","moa":"CD19|BCMA","graph1":"Immunology","graph2":"IND Enabling","graph3":"Qihan Biotech","amount2":0,"highestDevelopmentShortName":"IND","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Qihan Biotech \/ Undisclosed","highestDevelopmentStatusID":"5","companyTruncated":"Qihan Biotech \/ Undisclosed"},{"orgOrder":0,"company":"Shenzhen Chipscreen Biosciences","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Immunology","country":"CHINA","productType":"Miscellaneous","year":"2020","type":"Inapplicable","leadProduct":"CS12192","moa":"JAK3\/JAK1","graph1":"Immunology","graph2":"IND Enabling","graph3":"Shenzhen Chipscreen Biosciences","amount2":0,"highestDevelopmentShortName":"IND","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Shenzhen Chipscreen Biosciences \/ Undisclosed","highestDevelopmentStatusID":"5","companyTruncated":"Shenzhen Chipscreen Biosciences \/ Undisclosed"},{"orgOrder":0,"company":"InnoCare Pharma","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Immunology","country":"CHINA","productType":"Miscellaneous","year":"2021","type":"Inapplicable","leadProduct":"ICP-332","moa":"TYK2","graph1":"Immunology","graph2":"IND Enabling","graph3":"InnoCare Pharma","amount2":0,"highestDevelopmentShortName":"IND","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"InnoCare Pharma \/ Undisclosed","highestDevelopmentStatusID":"5","companyTruncated":"InnoCare Pharma \/ Undisclosed"},{"orgOrder":0,"company":"Longbio Pharma","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Immunology","country":"CHINA","productType":"Miscellaneous","year":"2024","type":"Inapplicable","leadProduct":"LP-003","moa":"Undisclosed","graph1":"Immunology","graph2":"IND Enabling","graph3":"Longbio Pharma","amount2":0,"highestDevelopmentShortName":"IND","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Longbio Pharma \/ Undisclosed","highestDevelopmentStatusID":"5","companyTruncated":"Longbio Pharma \/ Undisclosed"},{"orgOrder":0,"company":"Biocytogen","sponsor":"Chia Tai Tianqing Pharmaceutical Group","pharmaFlowCategory":"DU","therapeuticArea":"Immunology","country":"CHINA","productType":"Undisclosed","year":"2025","type":"Inapplicable","leadProduct":"NTB003","moa":"Undisclosed","graph1":"Immunology","graph2":"IND Enabling","graph3":"Biocytogen","amount2":0,"highestDevelopmentShortName":"IND","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Biocytogen \/ Chia Tai Tianqing Pharmaceutical Group","highestDevelopmentStatusID":"5","companyTruncated":"Biocytogen \/ Chia Tai Tianqing Pharmaceutical Group"},{"orgOrder":0,"company":"Triastek","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Immunology","country":"CHINA","productType":"Miscellaneous","year":"2021","type":"Inapplicable","leadProduct":"T19","moa":"Undisclosed","graph1":"Immunology","graph2":"IND Enabling","graph3":"Triastek","amount2":0,"highestDevelopmentShortName":"IND","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"Tablet","sponsorNew":"Triastek \/ Undisclosed","highestDevelopmentStatusID":"5","companyTruncated":"Triastek \/ Undisclosed"},{"orgOrder":0,"company":"Triastek","sponsor":"Matrix Partners China","pharmaFlowCategory":"D","therapeuticArea":"Immunology","country":"CHINA","productType":"Miscellaneous","year":"2021","type":"Series B Financing","leadProduct":"T19","moa":"Undisclosed","graph1":"Immunology","graph2":"IND Enabling","graph3":"Triastek","amount2":0.050000000000000003,"highestDevelopmentShortName":"IND","therapeuticAreaShortName":"Immunology","amount2New":0.050000000000000003,"dosageForm":"Tablet","sponsorNew":"Triastek \/ Matrix Partners China","highestDevelopmentStatusID":"5","companyTruncated":"Triastek \/ Matrix Partners China"},{"orgOrder":0,"company":"Genrix Bio","sponsor":"Cullinan Therapeutics","pharmaFlowCategory":"D","therapeuticArea":"Immunology","country":"CHINA","productType":"Undisclosed","year":"2025","type":"Licensing Agreement","leadProduct":"Velinotamig","moa":"Undisclosed","graph1":"Immunology","graph2":"IND Enabling","graph3":"Genrix Bio","amount2":0.70999999999999996,"highestDevelopmentShortName":"IND","therapeuticAreaShortName":"Immunology","amount2New":0.70999999999999996,"dosageForm":"Injection","sponsorNew":"Genrix Bio \/ Cullinan Therapeutics","highestDevelopmentStatusID":"5","companyTruncated":"Genrix Bio \/ Cullinan Therapeutics"},{"orgOrder":0,"company":"Leads Biolabs","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Immunology","country":"CHINA","productType":"Protein","year":"2025","type":"Inapplicable","leadProduct":"LBL-047","moa":"BDCA2\/TACI","graph1":"Immunology","graph2":"IND Enabling","graph3":"Leads Biolabs","amount2":0,"highestDevelopmentShortName":"IND","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Leads Biolabs \/ Undisclosed","highestDevelopmentStatusID":"5","companyTruncated":"Leads Biolabs \/ Undisclosed"},{"orgOrder":0,"company":"Leads Biolabs","sponsor":"Dianthus Therapeutics","pharmaFlowCategory":"D","therapeuticArea":"Immunology","country":"CHINA","productType":"Protein","year":"2025","type":"Licensing Agreement","leadProduct":"DNTH212","moa":"APRIL\/BAFF\/BDCA2","graph1":"Immunology","graph2":"IND Enabling","graph3":"Leads Biolabs","amount2":1,"highestDevelopmentShortName":"IND","therapeuticAreaShortName":"Immunology","amount2New":1,"dosageForm":"Undisclosed","sponsorNew":"Leads Biolabs \/ Dianthus Therapeutics","highestDevelopmentStatusID":"5","companyTruncated":"Leads Biolabs \/ Dianthus Therapeutics"}]

Find Clinical Drug Development Pipelines & Deals | PipelineProspector

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                          Top Deals by Deal Size (USD bn)

                          01

                          ACI Convention
                          Not Confirmed
                          ACI Convention
                          Not Confirmed

                          Details : Through the licensing deal for DNTH212, undisclosed company aims to target APRIL/BAFF/BDCA2 in severe autoimmune diseases.

                          Product Name : DNTH212

                          Product Type : Protein

                          Upfront Cash : $30.0 million

                          October 16, 2025

                          Lead Product(s) : DNTH212

                          Therapeutic Area : Immunology

                          Highest Development Status : IND Enabling

                          Sponsor : Dianthus Therapeutics

                          Deal Size : $1,000.0 million

                          Deal Type : Licensing Agreement

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                          02

                          ACI Convention
                          Not Confirmed
                          ACI Convention
                          Not Confirmed

                          Details : LBL-047 is a bispecific fusion protein composed of a humanized anti-blood dendritic cell antigen 2 (BDCA2) antibody and an engineered transmembrane activator and CAML interactor.

                          Product Name : LBL-047

                          Product Type : Protein

                          Upfront Cash : Inapplicable

                          September 22, 2025

                          Lead Product(s) : LBL-047

                          Therapeutic Area : Immunology

                          Highest Development Status : IND Enabling

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          03

                          ACI Convention
                          Not Confirmed
                          ACI Convention
                          Not Confirmed

                          Details : QT-019B is an off-the-shelf allogeneic CAR-T cell therapy targeting CD19 and BCMA for the treatment of for refractory systemic lupus erythematosus.

                          Product Name : QT-019B

                          Product Type : Cell & Gene Therapy

                          Upfront Cash : Inapplicable

                          August 18, 2025

                          Lead Product(s) : QT-019B

                          Therapeutic Area : Immunology

                          Highest Development Status : IND Enabling

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          04

                          ACI Convention
                          Not Confirmed
                          ACI Convention
                          Not Confirmed

                          Details : Under the licensing agreement, Cullinan will holds the exclusive rights to develop and commercialize GR-1803 (velinotamig) in all disease areas globally outside of Greater China.

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : $20.0 million

                          June 05, 2025

                          Lead Product(s) : Velinotamig

                          Therapeutic Area : Immunology

                          Highest Development Status : IND Enabling

                          Sponsor : Cullinan Therapeutics

                          Deal Size : $712.0 million

                          Deal Type : Licensing Agreement

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                          05

                          ACI Convention
                          Not Confirmed
                          ACI Convention
                          Not Confirmed

                          Details : NTB003 is a second-generation fully human anti-IGF-1R monoclonal antibody, being investigated for thyroid eye disease.

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : Inapplicable

                          June 04, 2025

                          Lead Product(s) : NTB003

                          Therapeutic Area : Immunology

                          Highest Development Status : IND Enabling

                          Sponsor : Chia Tai Tianqing Pharmaceutical Group

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          06

                          ACI Convention
                          Not Confirmed
                          ACI Convention
                          Not Confirmed

                          Details : UC101 is the world’s first FDA IND-approved umbilical cord blood-derived allogeneic CAR-T therapy. It is being evaluated to alleviate the risk of host-versus-graft response.

                          Product Name : Undisclosed

                          Product Type : Cell & Gene Therapy

                          Upfront Cash : Inapplicable

                          January 29, 2025

                          Lead Product(s) : UC101

                          Therapeutic Area : Immunology

                          Highest Development Status : IND Enabling

                          Sponsor : VectorBuilder

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          07

                          ACI Convention
                          Not Confirmed
                          ACI Convention
                          Not Confirmed

                          Details : LP-003 is the company's next-generation anti-IgE antibody. Currently, it is being evaluated in the early-stage clinical trial studies for the treatment of food allergy.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          November 25, 2024

                          Lead Product(s) : LP-003

                          Therapeutic Area : Immunology

                          Highest Development Status : IND Enabling

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          08

                          ACI Convention
                          Not Confirmed
                          ACI Convention
                          Not Confirmed

                          Details : Fucaso (equecabtagene autoleucel) is a BCMA chimeric antigen receptor autologous T cell therapy, being investigated for the treatment of Non-renal Systemic Lupus Erythematosus.

                          Product Name : Undisclosed

                          Product Type : Cell & Gene Therapy

                          Upfront Cash : Inapplicable

                          August 12, 2024

                          Lead Product(s) : Equecabtagene Autoleucel

                          Therapeutic Area : Immunology

                          Highest Development Status : IND Enabling

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          09

                          ACI Convention
                          Not Confirmed
                          ACI Convention
                          Not Confirmed

                          Details : IASO-782 Injection is a fully human monoclonal antibody targeting human CD19, with Fc mutations to enhance ADCC function for treatment of Systemic Lupus Erythematosus.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          July 25, 2024

                          Lead Product(s) : IASO-782

                          Therapeutic Area : Immunology

                          Highest Development Status : IND Enabling

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          10

                          ACI Convention
                          Not Confirmed
                          ACI Convention
                          Not Confirmed

                          Details : CT103A (equecabtagene autoleucel) is a BCMA chimeric antigen receptor autologous T cell therapy, being investigated for the treatment of Generalized Myasthenia Gravis.

                          Product Name : Undisclosed

                          Product Type : Cell & Gene Therapy

                          Upfront Cash : Inapplicable

                          April 03, 2024

                          Lead Product(s) : Equecabtagene Autoleucel

                          Therapeutic Area : Immunology

                          Highest Development Status : IND Enabling

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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