
Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target

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Lead Product(s) : IMPT-314
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Lyell Immunopharma
Deal Size : $30.0 million
Deal Type : Acquisition
Lyell Immunopharma Completes Acquisition of ImmPACT Bio
Details : Lyell will acquire worldwide rights to ImmPACT’s pipeline, the next- gen CD19/CD20 autologous CAR T-cell therapy, which includes IMPT-314, it is currently in clinical development for B-cell lymphoma.
Product Name : Undisclosed
Product Type : Cell & Gene Therapy
Upfront Cash : $30.0 million
October 31, 2024
Lead Product(s) : IMPT-314
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Lyell Immunopharma
Deal Size : $30.0 million
Deal Type : Acquisition

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Lead Product(s) : IMPT-314
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Lyell Immunopharma
Deal Size : $30.0 million
Deal Type : Acquisition
Lyell Immunopharma Acquires ImmPACT Bio, Refocuses on CAR T-cell Therapy
Details : Lyell will acquire worldwide rights to ImmPACT’s pipeline, the next- gen CD19/CD20 autologous CAR T-cell therapy, which includes IMPT-314, it is currently in clinical development for B-cell lymphoma.
Product Name : Undisclosed
Product Type : Cell & Gene Therapy
Upfront Cash : $30.0 million
October 24, 2024
Lead Product(s) : IMPT-314
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Lyell Immunopharma
Deal Size : $30.0 million
Deal Type : Acquisition

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Lead Product(s) : IMPT-514
Therapeutic Area : Neurology
Study Phase : IND Enabling
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
ImmPACT Bio Wins FDA Clearance for CD19/CD20 CAR-T Therapy in Multiple Sclerosis
Details : IMPT-514 is a CD19/CD20-targeting chimeric antigen receptor (CAR) T-cell therapy that utilizes a potent bispecific CAR and a 4-1BB, which is under development for Multiple Sclerosis.
Product Name : Undisclosed
Product Type : Cell & Gene Therapy
Upfront Cash : Inapplicable
August 21, 2024
Lead Product(s) : IMPT-514
Therapeutic Area : Neurology
Highest Development Status : IND Enabling
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : IMPT-314
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : IMPT-314 is a bispecific autologous CAR T-cell therapy targeting the B-cell antigens CD19 and CD20. It was granted FDA fast track designation and will be studied in patients with aggressive B-cell lymphoma, including diffuse large B-cell lymphoma (DLBCL)...
Product Name : Undisclosed
Product Type : Cell & Gene Therapy
Upfront Cash : Inapplicable
May 15, 2023
Lead Product(s) : IMPT-314
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : IMPT-314
Therapeutic Area : Oncology
Study Phase : IND Enabling
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : IMPT-314, a bispecific “OR-Gate” autologous CAR T-cell therapy targeting the B-cell antigens CD19 and CD20. IMPT-314 will be studied in a Phase 1/2 clinical trial in patients with aggressive B-cell lymphoma, including diffuse large B-cell lymphoma (D...
Product Name : Undisclosed
Product Type : Cell & Gene Therapy
Upfront Cash : Inapplicable
January 24, 2023
Lead Product(s) : IMPT-314
Therapeutic Area : Oncology
Highest Development Status : IND Enabling
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

Details : In addition, ImmPACT Bio provided an update to the Phase 1 clinical study evaluating its CD19-CD20 bi-specific CAR T in patients with relapsed or refractory B-cell non-Hodgkin’s lymphoma (R/R B-cell NHL) at University of California, Los Angeles (UCLA).
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Undisclosed
January 20, 2022

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Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Study Phase : Undisclosed
Recipient : Kalthera
Deal Size : Undisclosed
Deal Type : Merger
ImmPACT Merger with Kalthera to Progress Next-Generation CAR Therapies Treatment
Details : Kalthera is currently progressing a clinical trial at the University of California, Los Angeles (UCLA) Jonsson Comprehensive Cancer Center with a pioneering bispecific chimeric antigen receptor (CAR) T-cell immunotherapy candidate targeting CD19/CD20.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Undisclosed
July 22, 2021
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Highest Development Status : Undisclosed
Recipient : Kalthera
Deal Size : Undisclosed
Deal Type : Merger
