[{"orgOrder":0,"company":"Immedica Pharma","sponsor":"Actinium pharmaceuticals","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Radiolabeled Compound","year":"2022","type":"Agreement","leadProduct":"131-I Apamistamab","moa":"||BC8","graph1":"Oncology","graph2":"Phase III","graph3":"Immedica Pharma","amount2":0.45000000000000001,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Oncology","amount2New":0.45000000000000001,"dosageForm":"Infusion","sponsorNew":"Immedica Pharma \/ Immedica Pharma","highestDevelopmentStatusID":"10","companyTruncated":"Immedica Pharma \/ Immedica Pharma"},{"orgOrder":0,"company":"Immedica Pharma","sponsor":"PharmaMar","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"SPAIN","productType":"Miscellaneous","year":"2020","type":"Agreement","leadProduct":"Lurbinectedin","moa":"DNA","graph1":"Oncology","graph2":"Phase II","graph3":"Immedica Pharma","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Injection","sponsorNew":"Immedica Pharma \/ Immedica Pharma","highestDevelopmentStatusID":"8","companyTruncated":"Immedica Pharma \/ Immedica Pharma"},{"orgOrder":0,"company":"Immedica Pharma","sponsor":"Marinus Pharmaceuticals","pharmaFlowCategory":"D","therapeuticArea":"Neurology","country":"U.S.A","productType":"Miscellaneous","year":"2024","type":"Acquisition","leadProduct":"Ganaxolone","moa":"GABA-A receptor; anion channel","graph1":"Neurology","graph2":"Approved FDF","graph3":"Immedica Pharma","amount2":0,"highestDevelopmentShortName":"Approved FDF","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Suspension","sponsorNew":"Immedica Pharma \/ Immedica Pharma","highestDevelopmentStatusID":"15","companyTruncated":"Immedica Pharma \/ Immedica Pharma"},{"orgOrder":0,"company":"Immedica Pharma","sponsor":"Ovid Therapeutics","pharmaFlowCategory":"D","therapeuticArea":"Neurology","country":"U.S.A","productType":"Miscellaneous","year":"2025","type":"Agreement","leadProduct":"Ganaxolone","moa":"GABA-A receptor; anion channel","graph1":"Neurology","graph2":"Approved FDF","graph3":"Immedica Pharma","amount2":0.01,"highestDevelopmentShortName":"Approved FDF","therapeuticAreaShortName":"Neurology","amount2New":0.01,"dosageForm":"Suspension","sponsorNew":"Immedica Pharma \/ Immedica Pharma","highestDevelopmentStatusID":"15","companyTruncated":"Immedica Pharma \/ Immedica Pharma"},{"orgOrder":0,"company":"Immedica Pharma","sponsor":"KKR","pharmaFlowCategory":"D","therapeuticArea":"Neurology","country":"SWEDEN","productType":"Enzyme","year":"2024","type":"Acquisition","leadProduct":"Pegzilarginase","moa":"L-arginine","graph1":"Neurology","graph2":"Approved FDF","graph3":"Immedica Pharma","amount2":0,"highestDevelopmentShortName":"Approved FDF","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Infusion","sponsorNew":"Immedica Pharma \/ KKR","highestDevelopmentStatusID":"15","companyTruncated":"Immedica Pharma \/ KKR"},{"orgOrder":0,"company":"Immedica Pharma","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Rare Diseases and Disorders","country":"SWEDEN","productType":"Enzyme","year":"2024","type":"Inapplicable","leadProduct":"Pegzilarginase","moa":"L-arginine","graph1":"Rare Diseases and Disorders","graph2":"Phase III","graph3":"Immedica Pharma","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Rare Diseases","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Immedica Pharma \/ Undisclosed","highestDevelopmentStatusID":"10","companyTruncated":"Immedica Pharma \/ Undisclosed"},{"orgOrder":0,"company":"Immedica Pharma","sponsor":"Aeglea BioTherapeutics","pharmaFlowCategory":"D","therapeuticArea":"Neurology","country":"U.S.A","productType":"Enzyme","year":"2021","type":"Licensing Agreement","leadProduct":"Pegzilarginase","moa":"L-arginine","graph1":"Neurology","graph2":"Phase III","graph3":"Immedica Pharma","amount2":0.14999999999999999,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Neurology","amount2New":0.14999999999999999,"dosageForm":"Infusion","sponsorNew":"Immedica Pharma \/ Immedica Pharma","highestDevelopmentStatusID":"10","companyTruncated":"Immedica Pharma \/ Immedica Pharma"},{"orgOrder":0,"company":"Immedica Pharma","sponsor":"Aeglea BioTherapeutics","pharmaFlowCategory":"D","therapeuticArea":"Neurology","country":"U.S.A","productType":"Enzyme","year":"2023","type":"Agreement","leadProduct":"Pegzilarginase","moa":"L-arginine","graph1":"Neurology","graph2":"Phase III","graph3":"Immedica Pharma","amount2":0.12,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Neurology","amount2New":0.12,"dosageForm":"Infusion","sponsorNew":"Immedica Pharma \/ Immedica Pharma","highestDevelopmentStatusID":"10","companyTruncated":"Immedica Pharma \/ Immedica Pharma"},{"orgOrder":0,"company":"Immedica Pharma","sponsor":"Helsinn Advanced Synthesis","pharmaFlowCategory":"D","therapeuticArea":"Gastroenterology","country":"SWITZERLAND","productType":"Miscellaneous","year":"2023","type":"Licensing Agreement","leadProduct":"Netupitant","moa":"||Neurokinin 1 receptor","graph1":"Gastroenterology","graph2":"Approved FDF","graph3":"Immedica Pharma","amount2":0,"highestDevelopmentShortName":"Approved FDF","therapeuticAreaShortName":"Gastroenterology","amount2New":0,"dosageForm":"Capsule","sponsorNew":"Immedica Pharma \/ Immedica Pharma","highestDevelopmentStatusID":"15","companyTruncated":"Immedica Pharma \/ Immedica Pharma"}]

Find Clinical Drug Pipeline Developments & Deals by Immedica Pharma

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                          Top Deals by Deal Size (USD bn)

                          01

                          Luxepack
                          Not Confirmed
                          Luxepack
                          Not Confirmed

                          Details : The agreement aims for strengthening Immedica’s focus on ganaxolone, for the adjunctive treatment of epileptic seizures, by acquiring control of additional intellectual property rights.

                          Product Name : Ztalmy

                          Product Type : Miscellaneous

                          Upfront Cash : $7.0 million

                          June 25, 2025

                          Lead Product(s) : Ganaxolone

                          Therapeutic Area : Neurology

                          Highest Development Status : Approved FDF

                          Recipient : Ovid Therapeutics

                          Deal Size : $7.0 million

                          Deal Type : Agreement

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                          02

                          Luxepack
                          Not Confirmed
                          Luxepack
                          Not Confirmed

                          Details : Through the acquisition, Immedica strengthens it's global rare disease business by adding Ztalmy (ganaxalone). It is indicated for the treatment of seizures associated with CDKL5 deficiency disorder.

                          Product Name : Ztalmy

                          Product Type : Miscellaneous

                          Upfront Cash : Undisclosed

                          December 30, 2024

                          Lead Product(s) : Ganaxolone

                          Therapeutic Area : Neurology

                          Highest Development Status : Approved FDF

                          Recipient : Marinus Pharmaceuticals

                          Deal Size : Undisclosed

                          Deal Type : Acquisition

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                          03

                          Luxepack
                          Not Confirmed
                          Luxepack
                          Not Confirmed

                          Details : Pegzilarginase is a Enzyme drug candidate, which is currently being evaluated in phase III clinical studies for the treatment of Arginase 1 Deficiency.

                          Product Name : Undisclosed

                          Product Type : Enzyme

                          Upfront Cash : Inapplicable

                          September 03, 2024

                          Lead Product(s) : Pegzilarginase

                          Therapeutic Area : Rare Diseases and Disorders

                          Highest Development Status : Phase III

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          04

                          Luxepack
                          Not Confirmed
                          Luxepack
                          Not Confirmed

                          Details : KKR and Impilo will support Immedica’s growth, including launching the approved ultra-orphan drug Loargys (pegzilarginase) and continuing in-licensing and M&A activities.

                          Product Name : Loargys

                          Product Type : Enzyme

                          Upfront Cash : Undisclosed

                          April 22, 2024

                          Lead Product(s) : Pegzilarginase

                          Therapeutic Area : Neurology

                          Highest Development Status : Approved FDF

                          Sponsor : KKR

                          Deal Size : Undisclosed

                          Deal Type : Acquisition

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                          05

                          Luxepack
                          Not Confirmed
                          Luxepack
                          Not Confirmed

                          Details : Under the agreement, Immedica gains global rights of AEB1102 (pegzilarginase), a novel recombinant human enzyme engineered to degrade the amino acid arginine, for the treatment of rare metabolic disease Arginase 1 Deficiency.

                          Product Name : Undisclosed

                          Product Type : Enzyme

                          Upfront Cash : $15.0 million

                          July 27, 2023

                          Lead Product(s) : Pegzilarginase

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase III

                          Recipient : Aeglea BioTherapeutics

                          Deal Size : $115.0 million

                          Deal Type : Agreement

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                          06

                          Luxepack
                          Not Confirmed
                          Luxepack
                          Not Confirmed

                          Details : Akynzeo (netupitant) is a 5-HT3 and NK1 receptor antagonist fixed combination approved in Europe in adults for the prevention of acute and delayed nausea and vomiting associated with cisplatin-based highly emetogenic chemotherapy and moderately emetogeni...

                          Product Name : Akynzeo

                          Product Type : Miscellaneous

                          Upfront Cash : Undisclosed

                          January 24, 2023

                          Lead Product(s) : Netupitant,Palonosetron

                          Therapeutic Area : Gastroenterology

                          Highest Development Status : Approved FDF

                          Recipient : Helsinn Advanced Synthesis

                          Deal Size : Undisclosed

                          Deal Type : Licensing Agreement

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                          07

                          PREP
                          Not Confirmed
                          PREP
                          Not Confirmed

                          Details : Actinium retains all rights related to Iomab-B in the United States and the rest of the world, and will be responsible for certain clinical and regulatory activities and the manufacturing of Iomab-B.

                          Product Name : Iomab-B

                          Product Type : Radiolabeled Compound

                          Upfront Cash : $35.0 million

                          April 12, 2022

                          Lead Product(s) : 131-I Apamistamab,Fludarabine Phosphate

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Recipient : Actinium pharmaceuticals

                          Deal Size : $452.0 million

                          Deal Type : Agreement

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                          08

                          Luxepack
                          Not Confirmed
                          Luxepack
                          Not Confirmed

                          Details : Aeglea BioTherapeutics will supply pegzilarginase, a novel, recombinant human arginase 1 enzyme that has been shown to lower toxic levels of the amino acid arginine in patients with Arginase 1 Deficiency (ARG1-D).

                          Product Name : Undisclosed

                          Product Type : Enzyme

                          Upfront Cash : $21.5 million

                          March 22, 2021

                          Lead Product(s) : Pegzilarginase

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase III

                          Recipient : Aeglea BioTherapeutics

                          Deal Size : $151.5 million

                          Deal Type : Licensing Agreement

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                          09

                          Luxepack
                          Not Confirmed
                          Luxepack
                          Not Confirmed

                          Details : Immedica gets an exclusive distribution and marketing right of the anti-tumor drug lurbinectedin for territories that include the UK, Ireland, the Nordic countries, Middle East and North Africa.

                          Product Name : Zepzelca

                          Product Type : Miscellaneous

                          Upfront Cash : $2.1 million

                          April 29, 2020

                          Lead Product(s) : Lurbinectedin

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Recipient : PharmaMar

                          Deal Size : Undisclosed

                          Deal Type : Agreement

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