
Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target

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Lead Product(s) : Ganaxolone
Therapeutic Area : Neurology
Study Phase : Approved FDF
Recipient : Ovid Therapeutics
Deal Size : $7.0 million
Deal Type : Agreement
Ovid Therapeutics Enters Agreement with Immedica Pharma
Details : The agreement aims for strengthening Immedica’s focus on ganaxolone, for the adjunctive treatment of epileptic seizures, by acquiring control of additional intellectual property rights.
Product Name : Ztalmy
Product Type : Miscellaneous
Upfront Cash : $7.0 million
June 25, 2025
Lead Product(s) : Ganaxolone
Therapeutic Area : Neurology
Highest Development Status : Approved FDF
Recipient : Ovid Therapeutics
Deal Size : $7.0 million
Deal Type : Agreement

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Lead Product(s) : Ganaxolone
Therapeutic Area : Neurology
Study Phase : Approved FDF
Recipient : Marinus Pharmaceuticals
Deal Size : Undisclosed
Deal Type : Acquisition
Immedica to Acquire Biopharmaceutical Company Marinus Pharmaceuticals, Inc.
Details : Through the acquisition, Immedica strengthens it's global rare disease business by adding Ztalmy (ganaxalone). It is indicated for the treatment of seizures associated with CDKL5 deficiency disorder.
Product Name : Ztalmy
Product Type : Miscellaneous
Upfront Cash : Undisclosed
December 30, 2024
Lead Product(s) : Ganaxolone
Therapeutic Area : Neurology
Highest Development Status : Approved FDF
Recipient : Marinus Pharmaceuticals
Deal Size : Undisclosed
Deal Type : Acquisition

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Lead Product(s) : Pegzilarginase
Therapeutic Area : Rare Diseases and Disorders
Study Phase : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Pegzilarginase in Subjects <24 Months Old With Arginase 1 Deficiency
Details : Pegzilarginase is a Enzyme drug candidate, which is currently being evaluated in phase III clinical studies for the treatment of Arginase 1 Deficiency.
Product Name : Undisclosed
Product Type : Enzyme
Upfront Cash : Inapplicable
September 03, 2024
Lead Product(s) : Pegzilarginase
Therapeutic Area : Rare Diseases and Disorders
Highest Development Status : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Pegzilarginase
Therapeutic Area : Neurology
Study Phase : Approved FDF
Sponsor : KKR
Deal Size : Undisclosed
Deal Type : Acquisition
Kkr and Impilo Announce Strategic Partnership in Rare Disease Platform Immedica Pharma
Details : KKR and Impilo will support Immedica’s growth, including launching the approved ultra-orphan drug Loargys (pegzilarginase) and continuing in-licensing and M&A activities.
Product Name : Loargys
Product Type : Enzyme
Upfront Cash : Undisclosed
April 22, 2024
Lead Product(s) : Pegzilarginase
Therapeutic Area : Neurology
Highest Development Status : Approved FDF
Sponsor : KKR
Deal Size : Undisclosed
Deal Type : Acquisition

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Lead Product(s) : Pegzilarginase
Therapeutic Area : Neurology
Study Phase : Phase III
Recipient : Aeglea BioTherapeutics
Deal Size : $115.0 million
Deal Type : Agreement
Aeglea BioTherapeutics Announces Sale of Pegzilarginase to Immedica Pharma
Details : Under the agreement, Immedica gains global rights of AEB1102 (pegzilarginase), a novel recombinant human enzyme engineered to degrade the amino acid arginine, for the treatment of rare metabolic disease Arginase 1 Deficiency.
Product Name : Undisclosed
Product Type : Enzyme
Upfront Cash : $15.0 million
July 27, 2023
Lead Product(s) : Pegzilarginase
Therapeutic Area : Neurology
Highest Development Status : Phase III
Recipient : Aeglea BioTherapeutics
Deal Size : $115.0 million
Deal Type : Agreement

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Lead Product(s) : Netupitant,Palonosetron
Therapeutic Area : Gastroenterology
Study Phase : Approved FDF
Recipient : Helsinn Advanced Synthesis
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Details : Akynzeo (netupitant) is a 5-HT3 and NK1 receptor antagonist fixed combination approved in Europe in adults for the prevention of acute and delayed nausea and vomiting associated with cisplatin-based highly emetogenic chemotherapy and moderately emetogeni...
Product Name : Akynzeo
Product Type : Miscellaneous
Upfront Cash : Undisclosed
January 24, 2023
Lead Product(s) : Netupitant,Palonosetron
Therapeutic Area : Gastroenterology
Highest Development Status : Approved FDF
Recipient : Helsinn Advanced Synthesis
Deal Size : Undisclosed
Deal Type : Licensing Agreement

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Lead Product(s) : 131-I Apamistamab,Fludarabine Phosphate
Therapeutic Area : Oncology
Study Phase : Phase III
Recipient : Actinium pharmaceuticals
Deal Size : $452.0 million
Deal Type : Agreement
Details : Actinium retains all rights related to Iomab-B in the United States and the rest of the world, and will be responsible for certain clinical and regulatory activities and the manufacturing of Iomab-B.
Product Name : Iomab-B
Product Type : Radiolabeled Compound
Upfront Cash : $35.0 million
April 12, 2022
Lead Product(s) : 131-I Apamistamab,Fludarabine Phosphate
Therapeutic Area : Oncology
Highest Development Status : Phase III
Recipient : Actinium pharmaceuticals
Deal Size : $452.0 million
Deal Type : Agreement

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Lead Product(s) : Pegzilarginase
Therapeutic Area : Neurology
Study Phase : Phase III
Recipient : Aeglea BioTherapeutics
Deal Size : $151.5 million
Deal Type : Licensing Agreement
Aeglea BioTherapeutics and Immedica Announce Commercialization Agreement for Pegzilarginase
Details : Aeglea BioTherapeutics will supply pegzilarginase, a novel, recombinant human arginase 1 enzyme that has been shown to lower toxic levels of the amino acid arginine in patients with Arginase 1 Deficiency (ARG1-D).
Product Name : Undisclosed
Product Type : Enzyme
Upfront Cash : $21.5 million
March 22, 2021
Lead Product(s) : Pegzilarginase
Therapeutic Area : Neurology
Highest Development Status : Phase III
Recipient : Aeglea BioTherapeutics
Deal Size : $151.5 million
Deal Type : Licensing Agreement

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Lead Product(s) : Lurbinectedin
Therapeutic Area : Oncology
Study Phase : Phase I
Recipient : PharmaMar
Deal Size : Undisclosed
Deal Type : Agreement
Details : Immedica gets an exclusive distribution and marketing right of the anti-tumor drug lurbinectedin for territories that include the UK, Ireland, the Nordic countries, Middle East and North Africa.
Product Name : Zepzelca
Product Type : Miscellaneous
Upfront Cash : $2.1 million
April 29, 2020
Lead Product(s) : Lurbinectedin
Therapeutic Area : Oncology
Highest Development Status : Phase I
Recipient : PharmaMar
Deal Size : Undisclosed
Deal Type : Agreement
