
Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target

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Lead Product(s) : ICT01
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Ipsen
Deal Size : $1,156.9 million
Deal Type : Acquisition
Ipsen Acquires ImCheck Therapeutics, Expanding Oncology Leadership
Details : Through the acquisition of ICT01, an unconjugated antibody targeting BTN3A/gamma-9-delta-2 T-cell, the deal aims to advance treatment options for Acute Myeloid Leukemia (AML).
Product Name : ICT01
Product Type : Antibody, Unconjugated
Upfront Cash : $404.9 million
October 22, 2025
Lead Product(s) : ICT01
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Ipsen
Deal Size : $1,156.9 million
Deal Type : Acquisition

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Lead Product(s) : ICT01,Azacitidine,Venetoclax
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
ImCheck's ICT01 Receives FDA Fast Track for AML Combo Treatment
Details : ImCheck receives fDA fast track designation for ICT01 in Combination with Azacitidine and Venetoclax in first-line acute myeloid leukemia for patients unfit for induction chemotherapy treatment.
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Inapplicable
September 18, 2024
Lead Product(s) : ICT01,Azacitidine,Venetoclax
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : ICT01,Pembrolizumab
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Bpifrance
Deal Size : $22.4 million
Deal Type : Funding
ImCheck Receives €20.18M from French Government For Drug Development
Details : The funding will support company’s ICT01, a pathogen-agnostic γ9δ2 T cell-activating monoclonal antibody, currently in a Phase I/IIa in various solid cancer and hematologic malignancy indications.
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Undisclosed
August 29, 2024
Lead Product(s) : ICT01,Pembrolizumab
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Bpifrance
Deal Size : $22.4 million
Deal Type : Funding

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Lead Product(s) : ICT01
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
ImCheck Presents Initial Patient Data from the EVICTION-2 Clinical Trial at SITC Annual Meeting
Details : The combination also demonstrated the activation, mobilization, and proliferation of CD8 T cells and NKs, with slightly more modest effects on granulocytes, in most patients at lower ICT01 doses than shown in previously presented data of ICT01 monotherap...
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Inapplicable
November 11, 2022
Lead Product(s) : ICT01
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : ICT01,Pembrolizumab
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Broad antitumor immune responses and demonstration of durable disease control from solid tumor patients who previously failed one or more checkpoint-inhibitor regimen, across a range of ICT01 doses in combination with pembrolizumab.
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Inapplicable
September 10, 2022
Lead Product(s) : ICT01,Pembrolizumab
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : ICT01,Pembrolizumab
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Earlybird
Deal Size : $103.0 million
Deal Type : Series C Financing
Details : The proceeds will be used to support the Phase IIa expansion arms of EVICTION in solid tumors and hematologic cancers, and completion of placebo-controlled clinical trials evaluating ImCheck’s lead candidate ICT01 in combination with a PD-1 inhibitor f...
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Undisclosed
June 13, 2022
Lead Product(s) : ICT01,Pembrolizumab
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Earlybird
Deal Size : $103.0 million
Deal Type : Series C Financing

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Lead Product(s) : ICT01,Pembrolizumab
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Clinical responses achieved with low doses of ICT01 in combination with pembrolizumab in solid tumor patients who previously failed checkpoint-inhibitor therapy support the complementary mechanisms of action with potential for anti-tumor activity.
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Inapplicable
April 08, 2022
Lead Product(s) : ICT01,Pembrolizumab
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : ICT01
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : ILife Consulting | Exystat
Deal Size : Inapplicable
Deal Type : Inapplicable
Phase 1/2a Study of ICT01 Plus Low Dose SC IL-2 in Patients With Advanced Solid Tumors
Details : ICT01 is a Antibody drug candidate, which is currently being evaluated in phase I/ phase II clinical studies for the treatment of Neoplasms.
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Inapplicable
April 01, 2022
Lead Product(s) : ICT01
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : ILife Consulting | Exystat
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : ICT01,Pembrolizumab
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Presented results demonstrating ICT01 plus pembrolizumab induced anti-tumor responses in patients with a range of solid tumors. 5 of 8 patients achieved disease control at 8 weeks and beyond according to RECIST1.1, including two partial responses at week...
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Inapplicable
November 12, 2021
Lead Product(s) : ICT01,Pembrolizumab
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : ICT01,Pembrolizumab
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : CT01 is a fully-humanized anti-BTN3A monoclonal antibody designed to selectively activate gamma 9 delta 2 (Vγ9Vδ2) T cells through all three isoforms of BTN3A (1/2/3). CT01 has been shown to have anti-tumor activity against a range of cancers.
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Inapplicable
October 20, 2021
Lead Product(s) : ICT01,Pembrolizumab
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
