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            BPZE1 is a next-generation live-attenuated pertussis vaccine designed to induce comprehensive and durable protection against B. pertussis infection (colonization) and disease (whooping cough).

            Lead Product(s): BPZE1

            Therapeutic Area: Infections and Infectious Diseases Product Name: BPZE1

            Highest Development Status: Phase II Product Type: Vaccine

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable September 05, 2023

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            BPZE1 is the most advanced next generation pertussis vaccine, designed to overcome deficiencies of current vaccines, including limited durability and the inability to prevent nasopharyngeal Bordetella pertussis infections that lead to transmission.

            Lead Product(s): Live-attenuated Bordetella Pertussis Vaccine,Azithromycin,Bordetella Pertussis Challenge Strain

            Therapeutic Area: Infections and Infectious Diseases Product Name: BPZE1

            Highest Development Status: Phase II Product Type: Vaccine

            Partner/Sponsor/Collaborator: Knott Partners

            Deal Size: $42.8 million Upfront Cash: Undisclosed

            Deal Type: Series D Financing September 06, 2022

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            BPZE1 is only next generation live-attenuated intranasal pertussis vaccine in clinical trials designed to protect against Bordetella pertussis nasal infection and active disease through induction of broad and sustained mucosal and systemic immunity.

            Lead Product(s): BPZE1

            Therapeutic Area: Infections and Infectious Diseases Product Name: BPZE1

            Highest Development Status: Phase II Product Type: Vaccine

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable June 27, 2022

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            In addition to preclinical development of B-Tech Vector vaccines for TB and other targets, ILiAD continues to advance its BPZE1 pertussis vaccine through late-stage clinical development.

            Lead Product(s): Tuberculosis Vaccine

            Therapeutic Area: Infections and Infectious Diseases Product Name: Undisclosed

            Highest Development Status: Preclinical Product Type: Vaccine

            Partner/Sponsor/Collaborator: National Institutes of Health

            Deal Size: $1.0 million Upfront Cash: Undisclosed

            Deal Type: Funding April 26, 2022

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            Fast Track Designation for BPZE1 is based on the positive topline results from Phase 2b trial demonstrating that BPZE1 induced durable mucosal immunity and reduced nasal colonization and, it has the potential to address unmet medical needs for such a disease or condition.

            Lead Product(s): BPZE1

            Therapeutic Area: Infections and Infectious Diseases Product Name: BPZE1

            Highest Development Status: Phase II Product Type: Vaccine

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable January 03, 2022

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            BPZE1 is a live attenuated vaccine and next generation pertussis vaccine in advanced clinical trials which is designed to protect against Bordetella pertussis nasal infection and developed as a booster vaccine with future development investigating its application in infants.

            Lead Product(s): BPZE1

            Therapeutic Area: Infections and Infectious Diseases Product Name: BPZE1

            Highest Development Status: Phase II Product Type: Vaccine

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable September 29, 2021

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            Poster titled "Assessment Of Safety And Immunologic Responses Of BPZE1, An Intranasal Live Attenuated Pertussis Vaccine, In Healthy Adults" wil be presested at the conference.

            Lead Product(s): BPZE1

            Therapeutic Area: Infections and Infectious Diseases Product Name: BPZE1

            Highest Development Status: Phase II Product Type: Vaccine

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable October 21, 2020

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            BPZE1 prevented colonization from re-vaccination/challenge in 90% of subjects with no vaccine related serious adverse events.

            Lead Product(s): BPZE1

            Therapeutic Area: Infections and Infectious Diseases Product Name: BPZE1

            Highest Development Status: Phase II Product Type: Vaccine

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable September 29, 2020

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            Details:

            ILiAD Biotechnologies will be presenting new data from its Phase 2b clinical trial of lead pertussis vaccine candidate, BPZE1, at the World Vaccine Congress to be held virtually.

            Lead Product(s): BPZE1

            Therapeutic Area: Infections and Infectious Diseases Product Name: BPZE1

            Highest Development Status: Phase II Product Type: Vaccine

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable September 24, 2020

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