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    [{"orgOrder":0,"company":"Icosavax","sponsor":"Bill & Melinda Gates Foundation","pharmaFlowCategory":"D","therapeuticArea":"Infections and Infectious Diseases","country":"U.S.A","productType":"Vaccine","year":"2020","type":"Funding","leadProduct":"IVX-411","moa":"SARS-CoV-2 S","graph1":"Infections and Infectious Diseases","graph2":"Preclinical","graph3":"Icosavax","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Icosavax \/ Bill & Melinda Gates Foundation","highestDevelopmentStatusID":"4","companyTruncated":"Icosavax \/ Bill & Melinda Gates Foundation"},{"orgOrder":0,"company":"Icosavax","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"U.S.A","productType":"Vaccine","year":"2022","type":"Inapplicable","leadProduct":"IVX-411","moa":"SARS-CoV-2 S","graph1":"Infections and Infectious 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Management"},{"orgOrder":0,"company":"Icosavax","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"U.S.A","productType":"Vaccine","year":"2023","type":"Inapplicable","leadProduct":"IVX-241","moa":"||Undisclosed","graph1":"Infections and Infectious Diseases","graph2":"Phase II","graph3":"Icosavax","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Intramuscular Injection","sponsorNew":"Icosavax \/ Inapplicable","highestDevelopmentStatusID":"8","companyTruncated":"Icosavax \/ Inapplicable"},{"orgOrder":0,"company":"Icosavax","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"U.S.A","productType":"Vaccine","year":"2023","type":"Inapplicable","leadProduct":"IVX-241","moa":"||Undisclosed","graph1":"Infections and Infectious Diseases","graph2":"Phase II","graph3":"Icosavax","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Intramuscular Injection","sponsorNew":"Icosavax \/ Inapplicable","highestDevelopmentStatusID":"8","companyTruncated":"Icosavax \/ Inapplicable"},{"orgOrder":0,"company":"Icosavax","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"U.S.A","productType":"Vaccine","year":"2022","type":"Inapplicable","leadProduct":"IVX-241","moa":"||Undisclosed","graph1":"Infections and Infectious Diseases","graph2":"Phase II","graph3":"Icosavax","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Intramuscular Injection","sponsorNew":"Icosavax \/ Inapplicable","highestDevelopmentStatusID":"8","companyTruncated":"Icosavax \/ 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Inapplicable"},{"orgOrder":0,"company":"Icosavax","sponsor":"AstraZeneca","pharmaFlowCategory":"D","therapeuticArea":"Infections and Infectious Diseases","country":"U.S.A","productType":"Vaccine","year":"2024","type":"Acquisition","leadProduct":"IVX-A12","moa":"Undisclosed","graph1":"Infections and Infectious Diseases","graph2":"Phase II","graph3":"Icosavax","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Intramuscular Injection","sponsorNew":"Icosavax \/ AstraZeneca","highestDevelopmentStatusID":"8","companyTruncated":"Icosavax \/ AstraZeneca"},{"orgOrder":0,"company":"Icosavax","sponsor":"AstraZeneca","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"U.S.A","productType":"Vaccine","year":"2023","type":"Inapplicable","leadProduct":"IVX-A12","moa":"Undisclosed","graph1":"Infections and Infectious Diseases","graph2":"Phase II","graph3":"Icosavax","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Intramuscular Injection","sponsorNew":"Icosavax \/ AstraZeneca","highestDevelopmentStatusID":"8","companyTruncated":"Icosavax \/ AstraZeneca"},{"orgOrder":0,"company":"Icosavax","sponsor":"AstraZeneca","pharmaFlowCategory":"D","therapeuticArea":"Infections and Infectious Diseases","country":"U.S.A","productType":"Vaccine","year":"2023","type":"Acquisition","leadProduct":"IVX-A12","moa":"Undisclosed","graph1":"Infections and Infectious Diseases","graph2":"Phase II","graph3":"Icosavax","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Intramuscular Injection","sponsorNew":"Icosavax \/ AstraZeneca","highestDevelopmentStatusID":"8","companyTruncated":"Icosavax \/ AstraZeneca"},{"orgOrder":0,"company":"Icosavax","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"U.S.A","productType":"Vaccine","year":"2023","type":"Inapplicable","leadProduct":"IVX-241","moa":"||Undisclosed","graph1":"Infections and Infectious Diseases","graph2":"Phase II","graph3":"Icosavax","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Intramuscular Injection","sponsorNew":"Icosavax \/ Inapplicable","highestDevelopmentStatusID":"8","companyTruncated":"Icosavax \/ Inapplicable"},{"orgOrder":0,"company":"Icosavax","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"U.S.A","productType":"Vaccine","year":"2023","type":"Inapplicable","leadProduct":"IVX-241","moa":"||Undisclosed","graph1":"Infections and Infectious Diseases","graph2":"Phase II","graph3":"Icosavax","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Intramuscular Injection","sponsorNew":"Icosavax \/ Inapplicable","highestDevelopmentStatusID":"8","companyTruncated":"Icosavax \/ Inapplicable"}]

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                            01

                            Icosavax

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                            AACR Annual meeting
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                            Icosavax

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                            AACR Annual meeting
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                            Lead Product(s) : IVX-A12

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase II

                            Sponsor : AstraZeneca

                            Deal Size : $1,100.0 million

                            Deal Type : Acquisition

                            DEALS_DEV arrow-down

                            Acquisition of Icosavax Completed

                            Details : AstraZeneca acquires Icosavax’s IVX-A12, a combination protein vaccine for RSV and human metapneumovirus, targeting older adults.

                            Product Name : IVX-A12

                            Product Type : Vaccine

                            Upfront Cash : $1,100.0 million

                            February 19, 2024

                            Lead Product(s) : IVX-A12

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase II

                            Sponsor : AstraZeneca

                            Deal Size : $1,100.0 million

                            Deal Type : Acquisition

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                            02

                            Icosavax

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                            AACR Annual meeting
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                            Icosavax

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                            AACR Annual meeting
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                            Lead Product(s) : IVX-A12

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase II

                            Sponsor : AstraZeneca

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Icosavax Announces Positive Topline Interim Phase 2 Results for Combination VLP Vaccine Candidate IVX-A12 Agai...

                            Details : IVX-A12 is a combination virus like particle (VLP) vaccine candidate targeting both respiratory syncytial virus (RSV) and human metapneumovirus (hMPV). It is under phase 2 clinical development.

                            Product Name : IVX-A12

                            Product Type : Vaccine

                            Upfront Cash : Inapplicable

                            December 12, 2023

                            Lead Product(s) : IVX-A12

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase II

                            Sponsor : AstraZeneca

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

                            Icosavax

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                            AACR Annual meeting
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                            Icosavax

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                            AACR Annual meeting
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                            Lead Product(s) : IVX-A12

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase II

                            Sponsor : AstraZeneca

                            Deal Size : $1,100.0 million

                            Deal Type : Acquisition

                            DEALS_DEV arrow-down

                            Icosavax, Inc. Announces Agreement to be Acquired by AstraZeneca

                            Details : Through the acquisition of Icosavax, AstraZeneca gains access to IVX-A12, a combination virus like particle (VLP) vaccine candidate targeting both respiratory syncytial virus (RSV) and human metapneumovirus (hMPV).

                            Product Name : IVX-A12

                            Product Type : Vaccine

                            Upfront Cash : $1,100.0 million

                            December 12, 2023

                            Lead Product(s) : IVX-A12

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase II

                            Sponsor : AstraZeneca

                            Deal Size : $1,100.0 million

                            Deal Type : Acquisition

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                            04

                            Icosavax

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                            AACR Annual meeting
                            Not Confirmed

                            Icosavax

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                            AACR Annual meeting
                            Not Confirmed
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                            Lead Product(s) : IVX-A12,IVX-241

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Icosavax Announces Positive Topline Interim Phase 2 Results for Combination VLP Vaccine Candidate IVX-A12 Agai...

                            Details : IVX-A12 (IVX-121, IVX-241) is a vaccine drug candidate, which is being evaluated for the treatment of patients with respiratory syncytial virus infection in adults.

                            Product Name : IVX-A12

                            Product Type : Vaccine

                            Upfront Cash : Inapplicable

                            December 12, 2023

                            Lead Product(s) : IVX-A12,IVX-241

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            05

                            Icosavax

                            U.S.A arrow
                            AACR Annual meeting
                            Not Confirmed

                            Icosavax

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                            AACR Annual meeting
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                            Lead Product(s) : IVX-A12

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Icosavax Reports Positive 12-Month Durability Data for VLP Vaccine Candidate IVX-121 Against RSV and Initial E...

                            Details : IVX-A12 is a potential first-in-class combination vaccine candidate containing VLPs that incorporate stabilized prefusion F proteins from RSV and hMPV viruses.

                            Product Name : IVX-A12

                            Product Type : Vaccine

                            Upfront Cash : Inapplicable

                            August 08, 2023

                            Lead Product(s) : IVX-A12

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            06

                            Icosavax

                            U.S.A arrow
                            AACR Annual meeting
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                            Icosavax

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                            AACR Annual meeting
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                            Lead Product(s) : IVX-A12,IVX-241

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Icosavax Initiates Phase 2 Trial of IVX-A12 Against RSV and hMPV in Older Adults

                            Details : IVX-A12 is a combination bivalent vaccine candidate against both respiratory syncytial virus and human metapneumovirus. IVX-A12 is comprised of IVX-121, Icosavax’s RSV prefusion F protein VLP and IVX-241, Icosavax’s hMPV prefusion F protein VLP vacci...

                            Product Name : IVX-A12

                            Product Type : Vaccine

                            Upfront Cash : Inapplicable

                            June 20, 2023

                            Lead Product(s) : IVX-A12,IVX-241

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            Icosavax

                            U.S.A arrow
                            AACR Annual meeting
                            Not Confirmed

                            Icosavax

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                            AACR Annual meeting
                            Not Confirmed
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                            Lead Product(s) : IVX-A12,IVX-241

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Icosavax Announces Positive Topline Interim Phase 1 Results for Bivalent VLP Vaccine Candidate IVX-A12 Against...

                            Details : IVX-A12 is a combination bivalent vaccine candidate against both respiratory syncytial virus and human metapneumovirus. IVX-A12 is comprised of IVX-121, Icosavax’s RSV prefusion F protein VLP and IVX-241, Icosavax’s hMPV prefusion F protein VLP vacci...

                            Product Name : IVX-A12

                            Product Type : Vaccine

                            Upfront Cash : Inapplicable

                            May 22, 2023

                            Lead Product(s) : IVX-A12,IVX-241

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            08

                            Icosavax

                            U.S.A arrow
                            AACR Annual meeting
                            Not Confirmed

                            Icosavax

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                            AACR Annual meeting
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                            Lead Product(s) : IVX-A12,IVX-241

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Icosavax Granted FDA Fast Track Designation for IVX-A12

                            Details : IVX-A12 is a combination bivalent vaccine candidate against both respiratory syncytial virus and human metapneumovirus. IVX-A12 is comprised of IVX-121, Icosavax’s RSV prefusion F protein VLP and IVX-241, Icosavax’s hMPV prefusion F protein VLP vacci...

                            Product Name : IVX-A12

                            Product Type : Vaccine

                            Upfront Cash : Inapplicable

                            February 21, 2023

                            Lead Product(s) : IVX-A12,IVX-241

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            09

                            Icosavax

                            U.S.A arrow
                            AACR Annual meeting
                            Not Confirmed

                            Icosavax

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                            AACR Annual meeting
                            Not Confirmed
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                            Lead Product(s) : IVX-A12

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Icosavax Reports Positive Durability Data for VLP Vaccine Candidate IVX-121 Against RSV at Six-Month Timepoint

                            Details : In new data from Phase 1/1b study, IVX-121 showed sustained immunologic response at six months; geometric mean titers (GMT) against RSV-A through day 180 persisting at 64-98% of the GMTs at day 28 in older adults.

                            Product Name : IVX-A12

                            Product Type : Vaccine

                            Upfront Cash : Inapplicable

                            December 13, 2022

                            Lead Product(s) : IVX-A12

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            10

                            Icosavax

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                            AACR Annual meeting
                            Not Confirmed

                            Icosavax

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                            AACR Annual meeting
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                            Lead Product(s) : IVX-411

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Preclinical

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Icosavax Announces Results from IVX-411 Drug Product Investigation and Outlines Additional Corporate Milestone...

                            Details : An in vivo assessment in mice demonstrated that instability of the RBD antigen on the VLP surface translated to a loss of potency for IVX-411 consistent with that seen in the company’s Phase 1/2 results.

                            Product Name : IVX-411

                            Product Type : Vaccine

                            Upfront Cash : Inapplicable

                            July 28, 2022

                            Lead Product(s) : IVX-411

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Preclinical

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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