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    [{"orgOrder":0,"company":"IAVI","sponsor":"GSK | Rockefeller University | George Washington University | Amsterdam UMC, VUmc","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"U.S.A","productType":"Vaccine","year":"2020","type":"Inapplicable","leadProduct":"BG505 SOSIP GT1.1 gp140 Vaccine, Adjuvanted","moa":"Undisclosed","graph1":"Infections and Infectious Diseases","graph2":"Phase I","graph3":"IAVI","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"IAVI \/ GSK | Rockefeller University | George Washington University | Amsterdam UMC, VUmc","highestDevelopmentStatusID":"6","companyTruncated":"IAVI \/ GSK | Rockefeller University | George Washington University | Amsterdam UMC, VUmc"},{"orgOrder":0,"company":"IAVI","sponsor":"3M Company | Access to Advanced Health Institute | Polymun Scientific Immunbiologische Forschung 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IAVI"},{"orgOrder":0,"company":"IAVI","sponsor":"Biofabri","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"SPAIN","productType":"Vaccine","year":"2025","type":"Inapplicable","leadProduct":"Mycobacterium Tuberculosis Vaccine, Live Attenuated","moa":"Undisclosed","graph1":"Infections and Infectious Diseases","graph2":"Phase III","graph3":"IAVI","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Injection","sponsorNew":"IAVI \/ IAVI","highestDevelopmentStatusID":"10","companyTruncated":"IAVI \/ IAVI"},{"orgOrder":0,"company":"IAVI","sponsor":"Bill & Melinda Gates Foundation","pharmaFlowCategory":"D","therapeuticArea":"Infections and Infectious Diseases","country":"U.S.A","productType":"Vaccine","year":"2023","type":"Funding","leadProduct":"Mycobacterium Tuberculosis Vaccine, Live Attenuated","moa":"Undisclosed","graph1":"Infections and Infectious 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IAVI","highestDevelopmentStatusID":"8","companyTruncated":"IAVI \/ IAVI"},{"orgOrder":0,"company":"IAVI","sponsor":"Merck Group","pharmaFlowCategory":"D","therapeuticArea":"Infections and Infectious Diseases","country":"U.S.A","productType":"Undisclosed","year":"2020","type":"Agreement","leadProduct":"Undisclosed","moa":"Undisclosed","graph1":"Infections and Infectious Diseases","graph2":"Discovery","graph3":"IAVI","amount2":0,"highestDevelopmentShortName":"Discovery","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"IAVI \/ Merck Group","highestDevelopmentStatusID":"2","companyTruncated":"IAVI \/ Merck Group"}]

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                            01

                            IAVI

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                            Lead Product(s) : Mycobacterium Tuberculosis Vaccine, Live Attenuated

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase III

                            Recipient : Biofabri

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            IAVI, Biofabri Start IMAGINE Trial for Tuberculosis Vaccine Candidate MTBVAC

                            Details : MTBVAC is a live-attenuated vaccine candidate, derived from a human isolate of Mycobacterium tuberculosis. It is being evaluated to prevent active TB lung disease in adolescents and adults.

                            Product Name : MTBVAC

                            Product Type : Vaccine

                            Upfront Cash : Inapplicable

                            February 26, 2025

                            Lead Product(s) : Mycobacterium Tuberculosis Vaccine, Live Attenuated

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase III

                            Recipient : Biofabri

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            02

                            IAVI

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                            Lead Product(s) : GRAdHIVNE1 vaccine

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase I

                            Sponsor : Ragon Institute | ReiThera | Mutala Trust

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            A Phase 1 Trial of a Gorilla Adenovirus Vectored Networked Epitopes Vaccine, Administered to Healthy Adults Li...

                            Details : GRAdHIVNE1 vaccine is a Vaccine drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of HIV Infections.

                            Product Name : Undisclosed

                            Product Type : Vaccine

                            Upfront Cash : Inapplicable

                            September 27, 2024

                            Lead Product(s) : GRAdHIVNE1 vaccine

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase I

                            Sponsor : Ragon Institute | ReiThera | Mutala Trust

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

                            IAVI

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                            Lead Product(s) : MOS1SIP

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase I

                            Sponsor : Polymun Scientific Immunbiologische Forschung GmbH

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            Mosaic HIV-1 Envelope Trimer Immunogens Administered to People Living with HIV (PLWH) in Africa

                            Details : MOS1SIP is a drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of HIV Infections.

                            Product Name : Undisclosed

                            Product Type : Undisclosed

                            Upfront Cash : Inapplicable

                            June 07, 2024

                            Lead Product(s) : MOS1SIP

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase I

                            Sponsor : Polymun Scientific Immunbiologische Forschung GmbH

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            04

                            IAVI

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                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase II

                            Recipient : HJF Medical Research International

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            Nigeria Hosts First Phase 2 Lassa Fever Vaccine Clinical Trial, Sponsored by IAVI

                            Details : A vaccine candidate, is being investigated in a phase 2 trial in above 2 years older Nigerian population for the prevention of Lassa fever virus infection.

                            Product Name : Undisclosed

                            Product Type : Undisclosed

                            Upfront Cash : Inapplicable

                            April 04, 2024

                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase II

                            Recipient : HJF Medical Research International

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            05

                            IAVI

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                            Lead Product(s) : Mycobacterium Tuberculosis Vaccine, Live Attenuated

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase III

                            Sponsor : Bill & Melinda Gates Foundation

                            Deal Size : $55.0 million

                            Deal Type : Funding

                            DEALS_DEV arrow-down

                            IAVI and Zendal Announce Funding for Efficacy Trial of Promising TB Vaccine Candidate in Africa

                            Details : The net proceeds will be used to conduct a Phase IIb trial assessing the safety and efficacy of the tuberculosis (TB) vaccine candidate MTBVAC to prevent active TB lung disease in adolescents and adults.

                            Product Name : MTBVAC

                            Product Type : Vaccine

                            Upfront Cash : Undisclosed

                            December 18, 2023

                            Lead Product(s) : Mycobacterium Tuberculosis Vaccine, Live Attenuated

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase III

                            Sponsor : Bill & Melinda Gates Foundation

                            Deal Size : $55.0 million

                            Deal Type : Funding

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                            06

                            IAVI

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                            Lead Product(s) : BG505 SOSIP.664 gp140 Vaccine, Adjuvanted

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase I

                            Sponsor : 3M Company | Access to Advanced Health Institute | Polymun Scientific Immunbiologische Forschung GmbH

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            A Study to Evaluate the Safety and Immunogenicity of 2 Doses of 100µg BG505 SOSIP.664 gp140 Vaccine, Adjuva...

                            Details : BG505 SOSIP.664 gp140 Vaccine, Adjuvanted is a Vaccine drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of HIV Infections.

                            Product Name : Undisclosed

                            Product Type : Vaccine

                            Upfront Cash : Inapplicable

                            August 09, 2023

                            Lead Product(s) : BG505 SOSIP.664 gp140 Vaccine, Adjuvanted

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase I

                            Sponsor : 3M Company | Access to Advanced Health Institute | Polymun Scientific Immunbiologische Forschung GmbH

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            IAVI

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                            Lead Product(s) : Mycobacterium Tuberculosis Vaccine, Live Attenuated

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase III

                            Sponsor : German Government

                            Deal Size : $10.0 million

                            Deal Type : Funding

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                            Germany Issues Award to IAVI to Support Development of the MTBVAC Tuberculosis Vaccine Candidate

                            Details : The funding will support the late-stage development of MTBVAC, a live, attenuated Mycobacterium tuberculosis vaccine, currently being developed as a potentially longer-lasting TB vaccine for newborns and for the prevention of TB disease in adults and ado...

                            Product Name : MTBVAC

                            Product Type : Vaccine

                            Upfront Cash : Undisclosed

                            July 07, 2023

                            Lead Product(s) : Mycobacterium Tuberculosis Vaccine, Live Attenuated

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase III

                            Sponsor : German Government

                            Deal Size : $10.0 million

                            Deal Type : Funding

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                            08

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                            Lead Product(s) : rVSV∆G-SEBOV-GP Vaccine

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase I

                            Sponsor : BARDA

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            IAVI Starts First-in-Human Phase I Clinical Trial of Single-Dose Sudan Virus Vaccine Candidate

                            Details : IAVI C108 (rVSV∆G-SUDV-GP) vaccine candidate for Sudan ebolavirus disease prevention, consisting of replicating vesicular stomatitis vector containing a Sudan ebolavirus glycoprotein immunogen.

                            Product Name : Undisclosed

                            Product Type : Vaccine

                            Upfront Cash : Inapplicable

                            June 27, 2023

                            Lead Product(s) : rVSV∆G-SEBOV-GP Vaccine

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase I

                            Sponsor : BARDA

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            IAVI

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                            IAVI

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                            • EDQM
                            • WHO-GMP
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                            Lead Product(s) : Mycobacterium Tuberculosis Vaccine, Live Attenuated

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase III

                            Recipient : Biofabri

                            Deal Size : Undisclosed

                            Deal Type : Agreement

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                            Zendal and IAVI Announce Expanded Agreement to Partner on Development of TB Vaccine Candidate MTBVAC

                            Details : Under the agreement, IAVI is supporting development, global regulatory strategy, resource mobilization, and access planning for the adolescent/adult tuberculosis (TB) vaccine candidate MTBVAC.

                            Product Name : MTBVAC

                            Product Type : Vaccine

                            Upfront Cash : Undisclosed

                            May 17, 2023

                            Lead Product(s) : Mycobacterium Tuberculosis Vaccine, Live Attenuated

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase III

                            Recipient : Biofabri

                            Deal Size : Undisclosed

                            Deal Type : Agreement

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                            IAVI

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                            IAVI

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                            • fda
                            • EDQM
                            • WHO-GMP
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                            Lead Product(s) : rVSVΔG-MARV-GP

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Preclinical

                            Sponsor : BARDA

                            Deal Size : $47.0 million

                            Deal Type : Funding

                            DEALS_DEV arrow-down

                            IAVI and BARDA Expand Partnership to Advance IAVI's Filovirus Vaccine Candidates

                            Details : The funding will be used in the development and testing of IAVI's single-dose vaccine candidates, rVSVΔG-MARV-GP and rVSVΔG-SUDV-GP, against the filoviruses Marburg virus (MARV) and Sudan ebolavirus (SUDV) respectively.

                            Product Name : rVSVΔG-MARV-GP

                            Product Type : Vaccine

                            Upfront Cash : Undisclosed

                            March 02, 2023

                            Lead Product(s) : rVSVΔG-MARV-GP

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Preclinical

                            Sponsor : BARDA

                            Deal Size : $47.0 million

                            Deal Type : Funding

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