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            Details:

            Under the agreement, HilleVax gain rights to Kangh’s hexavalent virus-like particle (VLP) vaccine candidate for norovirus, referred to by HilleVax as HIL-216, outside of Greater China.

            Lead Product(s): HIL-216

            Therapeutic Area: Infections and Infectious Diseases Product Name: HIL-216

            Highest Development Status: Preclinical Product Type: Vaccine

            Recipient: Chengdu Kanghua Biological Products

            Deal Size: $270.5 million Upfront Cash: $15.0 million

            Deal Type: Licensing Agreement January 08, 2024

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            HilleVax intends to use the net proceeds from the offering to fund the clinical development of HIL-214, a virus-like particle (VLP) based vaccine candidate in development for the prevention of moderate-to-severe acute gastroenteritis (AGE) caused by norovirus infection.

            Lead Product(s): HIL-214

            Therapeutic Area: Infections and Infectious Diseases Product Name: HIL-214

            Highest Development Status: Phase II Product Type: Vaccine

            Partner/Sponsor/Collaborator: J.P. Morgan

            Deal Size: $115.0 million Upfront Cash: Undisclosed

            Deal Type: Public Offering September 25, 2023

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            HilleVax intends to use the net proceeds from the offering to fund the clinical development of HIL-214, a virus-like particle (VLP) based vaccine candidate in development for the prevention of moderate-to-severe acute gastroenteritis caused by norovirus infection.

            Lead Product(s): HIL-214

            Therapeutic Area: Infections and Infectious Diseases Product Name: HIL-214

            Highest Development Status: Phase II/ Phase III Product Type: Vaccine

            Partner/Sponsor/Collaborator: J.P. Morgan

            Deal Size: $100.0 million Upfront Cash: Undisclosed

            Deal Type: Public Offering September 19, 2023

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            HIL-214, its investigational virus-like particle (VLP) based vaccine candidate for the prevention of moderate-to-severe norovirus-related acute gastroenteritis (AGE) in infants.

            Lead Product(s): HIL-214

            Therapeutic Area: Infections and Infectious Diseases Product Name: HIL-214

            Highest Development Status: Phase II/ Phase III Product Type: Vaccine

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable April 25, 2023

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            HIL-214 is a VLP based vaccine candidate in development for the prevention of moderate-to-severe acute gastroenteritis (AGE) caused by norovirus infection. Norovirus is the most common cause of viral acute gastroenteritis (AGE) worldwide.

            Lead Product(s): HIL-214

            Therapeutic Area: Infections and Infectious Diseases Product Name: HIL-214

            Highest Development Status: Phase II Product Type: Vaccine

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable December 05, 2022

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            Details:

            The primary objective of the trial is to evaluate the protective efficacy of HIL-214 against the first confirmed moderate or severe AGE event due to a HIL-214 vaccine strain, GI.1 or GII.4, that occurs prior to each subject reaching 12 months of age.

            Lead Product(s): HIL-214

            Therapeutic Area: Infections and Infectious Diseases Product Name: HIL-214

            Highest Development Status: Phase II/ Phase III Product Type: Vaccine

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable August 31, 2022

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            HIL-214 is bivalent vaccine candidate in development for prevention of AGE caused by norovirus infection, consists of virus-like particles which are designed to mimic structure of two major genotypes of norovirus, GI.1 and GII.4, and is co-formulated with an alum adjuvant.

            Lead Product(s): HIL-214

            Therapeutic Area: Infections and Infectious Diseases Product Name: HIL-214

            Highest Development Status: Phase II Product Type: Vaccine

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable July 20, 2022

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            Details:

            The proceeds of this financing support the further clinical development of HilleVax’s virus-like particle (VLP) based vaccine candidate, HIL-214, for the prevention of moderate-to-severe acute gastroenteritis caused by norovirus infection.

            Lead Product(s): HIL-214

            Therapeutic Area: Infections and Infectious Diseases Product Name: HIL-214

            Highest Development Status: Phase II Product Type: Vaccine

            Partner/Sponsor/Collaborator: Frazier Healthcare

            Deal Size: $135.0 million Upfront Cash: Undisclosed

            Deal Type: Financing September 08, 2021

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