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Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Hematology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Rigel Pharmaceuticals \/ Undisclosed","highestDevelopmentStatusID":"10","companyTruncated":"Rigel Pharmaceuticals \/ Undisclosed"},{"orgOrder":0,"company":"Rigel Pharmaceuticals","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Hematology","country":"U.S.A","productType":"Miscellaneous","year":"2022","type":"Inapplicable","leadProduct":"Fostamatinib Disodium Hexahydrate","moa":"Tyrosine-protein kinase SYK","graph1":"Hematology","graph2":"Phase III","graph3":"Rigel Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Hematology","amount2New":0,"dosageForm":"Tablet","sponsorNew":"Rigel Pharmaceuticals \/ Undisclosed","highestDevelopmentStatusID":"10","companyTruncated":"Rigel Pharmaceuticals \/ Undisclosed"},{"orgOrder":0,"company":"Rigel Pharmaceuticals","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Hematology","country":"U.S.A","productType":"Miscellaneous","year":"2020","type":"Inapplicable","leadProduct":"Fostamatinib Disodium Hexahydrate","moa":"Tyrosine-protein kinase SYK","graph1":"Hematology","graph2":"Phase III","graph3":"Rigel Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Hematology","amount2New":0,"dosageForm":"Tablet","sponsorNew":"Rigel Pharmaceuticals \/ Undisclosed","highestDevelopmentStatusID":"10","companyTruncated":"Rigel Pharmaceuticals \/ Undisclosed"},{"orgOrder":0,"company":"Rigel Pharmaceuticals","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Hematology","country":"U.S.A","productType":"Miscellaneous","year":"2022","type":"Inapplicable","leadProduct":"Fostamatinib Disodium Hexahydrate","moa":"Tyrosine-protein kinase SYK","graph1":"Hematology","graph2":"Phase III","graph3":"Rigel Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Hematology","amount2New":0,"dosageForm":"Tablet","sponsorNew":"Rigel Pharmaceuticals \/ Undisclosed","highestDevelopmentStatusID":"10","companyTruncated":"Rigel Pharmaceuticals \/ Undisclosed"},{"orgOrder":0,"company":"Rigel Pharmaceuticals","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Hematology","country":"U.S.A","productType":"Miscellaneous","year":"2020","type":"Inapplicable","leadProduct":"Fostamatinib Disodium Hexahydrate","moa":"Tyrosine-protein kinase SYK","graph1":"Hematology","graph2":"Phase III","graph3":"Rigel Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Hematology","amount2New":0,"dosageForm":"Tablet","sponsorNew":"Rigel Pharmaceuticals \/ Undisclosed","highestDevelopmentStatusID":"10","companyTruncated":"Rigel Pharmaceuticals \/ Undisclosed"},{"orgOrder":0,"company":"CSL Behring","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Hematology","country":"U.S.A","productType":"Undisclosed","year":"2014","type":"Inapplicable","leadProduct":"BE1116","moa":"Undisclosed","graph1":"Hematology","graph2":"Phase III","graph3":"CSL Behring","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Hematology","amount2New":0,"dosageForm":"Infusion","sponsorNew":"CSL Behring \/ Undisclosed","highestDevelopmentStatusID":"10","companyTruncated":"CSL Behring \/ Undisclosed"},{"orgOrder":0,"company":"Pfizer Inc","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Hematology","country":"U.S.A","productType":"Undisclosed","year":"2020","type":"Inapplicable","leadProduct":"PF-06462700","moa":"Undisclosed","graph1":"Hematology","graph2":"Phase III","graph3":"Pfizer Inc","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Hematology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Pfizer Inc \/ Undisclosed","highestDevelopmentStatusID":"10","companyTruncated":"Pfizer Inc \/ Undisclosed"},{"orgOrder":0,"company":"Cerus Corporation","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Hematology","country":"U.S.A","productType":"Undisclosed","year":"2012","type":"Inapplicable","leadProduct":"S303 RBCs","moa":"Undisclosed","graph1":"Hematology","graph2":"Phase III","graph3":"Cerus Corporation","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Hematology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Cerus Corporation \/ Undisclosed","highestDevelopmentStatusID":"10","companyTruncated":"Cerus Corporation \/ Undisclosed"},{"orgOrder":0,"company":"Cadrenal Therapeutics","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Hematology","country":"U.S.A","productType":"Miscellaneous","year":"2023","type":"Inapplicable","leadProduct":"Tecarfarin","moa":"Vitamin k epoxide reductase complex subunit 1 isoform 1","graph1":"Hematology","graph2":"Phase III","graph3":"Cadrenal Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Hematology","amount2New":0,"dosageForm":"Tablet","sponsorNew":"Cadrenal Therapeutics \/ Undisclosed","highestDevelopmentStatusID":"10","companyTruncated":"Cadrenal Therapeutics \/ Undisclosed"},{"orgOrder":0,"company":"Espero BioPharma","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Hematology","country":"U.S.A","productType":"Miscellaneous","year":"2015","type":"Inapplicable","leadProduct":"Tecarfarin","moa":"Vitamin k epoxide reductase complex subunit 1 isoform 1","graph1":"Hematology","graph2":"Phase III","graph3":"Espero BioPharma","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Hematology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Espero BioPharma \/ Undisclosed","highestDevelopmentStatusID":"10","companyTruncated":"Espero BioPharma \/ Undisclosed"}]

    Find Clinical Drug Development Pipelines & Deals | PipelineProspector

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                            01

                            X4 Pharmaceuticals

                            U.S.A arrow
                            OTS 2025
                            Not Confirmed

                            X4 Pharmaceuticals

                            U.S.A arrow
                            OTS 2025
                            Not Confirmed
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                            Lead Product(s) : Mavorixafor

                            Therapeutic Area : Hematology

                            Study Phase : Phase III

                            Sponsor : Empery Asset Management

                            Deal Size : $85.0 million

                            Deal Type : Private Placement

                            DEALS_DEV arrow-down

                            X4 Pharmaceuticals Announces Closing of Upsized $85 Million Private Placement

                            Details : The net proceeds from the placement for continued development towards a potential additional approval of Xolremdi (mavorixafor) in chronic neutropenia.

                            Product Name : Xolremdi

                            Product Type : Miscellaneous

                            Upfront Cash : Undisclosed

                            August 13, 2025

                            Lead Product(s) : Mavorixafor

                            Therapeutic Area : Hematology

                            Highest Development Status : Phase III

                            Sponsor : Empery Asset Management

                            Deal Size : $85.0 million

                            Deal Type : Private Placement

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                            02

                            X4 Pharmaceuticals

                            U.S.A arrow
                            OTS 2025
                            Not Confirmed

                            X4 Pharmaceuticals

                            U.S.A arrow
                            OTS 2025
                            Not Confirmed
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                            • WHO-GMP
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                            Lead Product(s) : Mavorixafor

                            Therapeutic Area : Hematology

                            Study Phase : Phase III

                            Sponsor : Stifel

                            Deal Size : $60.0 million

                            Deal Type : Financing

                            DEALS_DEV arrow-down

                            X4 Pharmaceuticals Announces $60 Million Equity Financing

                            Details : X4 expects to use the net proceeds for continued development towards a potential additional approval of Xolremdi (mavorixafor) in chronic neutropenia, in addition to the commercialization of WHIM.

                            Product Name : Xolremdi

                            Product Type : Miscellaneous

                            Upfront Cash : Undisclosed

                            August 12, 2025

                            Lead Product(s) : Mavorixafor

                            Therapeutic Area : Hematology

                            Highest Development Status : Phase III

                            Sponsor : Stifel

                            Deal Size : $60.0 million

                            Deal Type : Financing

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                            03

                            Cogent Biosciences

                            U.S.A arrow
                            OTS 2025
                            Not Confirmed

                            Cogent Biosciences

                            U.S.A arrow
                            OTS 2025
                            Not Confirmed
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                            Lead Product(s) : Bezuclastinib,Sunitinib

                            Therapeutic Area : Hematology

                            Study Phase : Phase III

                            Sponsor : J.P. Morgan

                            Deal Size : $230.0 million

                            Deal Type : Public Offering

                            DEALS_DEV arrow-down

                            Cogent Biosciences Closes Upsized Public Offering of Common Stock

                            Details : The net proceeds will be used to accelerate our CGT9486 (bezuclastinib), a selective tyrosine kinase inhibitor selectively targeting KIT activation loop mutations in systemic mastocytosis, launch.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Undisclosed

                            July 10, 2025

                            Lead Product(s) : Bezuclastinib,Sunitinib

                            Therapeutic Area : Hematology

                            Highest Development Status : Phase III

                            Sponsor : J.P. Morgan

                            Deal Size : $230.0 million

                            Deal Type : Public Offering

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                            04

                            Cogent Biosciences

                            U.S.A arrow
                            OTS 2025
                            Not Confirmed

                            Cogent Biosciences

                            U.S.A arrow
                            OTS 2025
                            Not Confirmed
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                            • EDQM
                            • WHO-GMP
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                            Lead Product(s) : Bezuclastinib,Sunitinib

                            Therapeutic Area : Hematology

                            Study Phase : Phase III

                            Sponsor : J.P. Morgan

                            Deal Size : $150.0 million

                            Deal Type : Public Offering

                            DEALS_DEV arrow-down

                            Cogent Biosciences Proposes $150M Public Offering of Common Stock

                            Details : The net proceeds will be used to accelerate our CGT9486 (bezuclastinib), a selective tyrosine kinase inhibitor selectively targeting KIT activation loop mutations in systemic mastocytosis, launch.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Undisclosed

                            July 08, 2025

                            Lead Product(s) : Bezuclastinib,Sunitinib

                            Therapeutic Area : Hematology

                            Highest Development Status : Phase III

                            Sponsor : J.P. Morgan

                            Deal Size : $150.0 million

                            Deal Type : Public Offering

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                            05

                            Cogent Biosciences

                            U.S.A arrow
                            OTS 2025
                            Not Confirmed

                            Cogent Biosciences

                            U.S.A arrow
                            OTS 2025
                            Not Confirmed
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                            • EDQM
                            • WHO-GMP
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                            Lead Product(s) : Bezuclastinib,Sunitinib

                            Therapeutic Area : Hematology

                            Study Phase : Phase III

                            Sponsor : SLR Capital Partners

                            Deal Size : Undisclosed

                            Deal Type : Financing

                            DEALS_DEV arrow-down

                            Cogent Biosciences Secures up to $400 Million in Non-Dilutive Financing

                            Details : The net proceeds will be used to accelerate our CGT9486 (bezuclastinib), a selective tyrosine kinase inhibitor selectively targeting KIT activation loop mutations in systemic mastocytosis, launch.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Undisclosed

                            June 11, 2025

                            Lead Product(s) : Bezuclastinib,Sunitinib

                            Therapeutic Area : Hematology

                            Highest Development Status : Phase III

                            Sponsor : SLR Capital Partners

                            Deal Size : Undisclosed

                            Deal Type : Financing

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                            06

                            Kedrion

                            U.S.A arrow
                            OTS 2025
                            Not Confirmed

                            Kedrion

                            U.S.A arrow
                            OTS 2025
                            Not Confirmed
                            • fda
                            • EDQM
                            • WHO-GMP
                            Virtual Booth Boost your online visibility by uploading your products, APIs, FDFs, intermediates, excipients, and services for free on PharmaCompass. Rank higher among suppliers and expand your reach across the internet efficiently and cost-effectively.

                            Lead Product(s) : Coagulation Factor X

                            Therapeutic Area : Hematology

                            Study Phase : Phase III

                            Sponsor : Worldwide Clinical Trials

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            A Study Investigating Coagadex in the Treatment AFXD Associated With AL Amyloidosis

                            Details : Coagadex (Coagulation Factor X) is a drug candidate, which is currently being evaluated in phase III clinical studies for the treatment of Factor X Deficiency.

                            Product Name : Coagadex

                            Product Type : Undisclosed

                            Upfront Cash : Inapplicable

                            May 08, 2025

                            Lead Product(s) : Coagulation Factor X

                            Therapeutic Area : Hematology

                            Highest Development Status : Phase III

                            Sponsor : Worldwide Clinical Trials

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            Omeros

                            U.S.A arrow
                            OTS 2025
                            Not Confirmed

                            Omeros

                            U.S.A arrow
                            OTS 2025
                            Not Confirmed
                            • fda
                            • EDQM
                            • WHO-GMP
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                            Lead Product(s) : Narsoplimab

                            Therapeutic Area : Hematology

                            Study Phase : Phase III

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            FDA Accepts Narsoplimab BLA for TA-TMA with Late September PDUFA Target

                            Details : OMS721 (narsoplimab) is an investigational fully human mAb inhibiting MASP-2, being investigated for the treatment of hematopoietic stem cell transplant-associated thrombotic microangiopathy.

                            Product Name : Undisclosed

                            Product Type : Antibody, Unconjugated

                            Upfront Cash : Inapplicable

                            May 06, 2025

                            Lead Product(s) : Narsoplimab

                            Therapeutic Area : Hematology

                            Highest Development Status : Phase III

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            08

                            Statera Biopharma

                            U.S.A arrow
                            OTS 2025
                            Not Confirmed

                            Statera Biopharma

                            U.S.A arrow
                            OTS 2025
                            Not Confirmed
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                            • EDQM
                            • WHO-GMP
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                            Lead Product(s) : Entolimod

                            Therapeutic Area : Hematology

                            Study Phase : Phase III

                            Sponsor : Tivic Health

                            Deal Size : $1.5 million

                            Deal Type : Licensing Agreement

                            DEALS_DEV arrow-down

                            Tivic Expands TLR5 Entolimod License to Treat Neutropenia

                            Details : Under the licensing agreement, Tivic will obtains the rights of Entolimod TMC (entolimod). Iti s an being evaluated for treating for individuals with Neutropenia.

                            Product Name : Undisclosed

                            Product Type : Peptide, Unconjugated

                            Upfront Cash : $1.5 million

                            April 15, 2025

                            Lead Product(s) : Entolimod

                            Therapeutic Area : Hematology

                            Highest Development Status : Phase III

                            Sponsor : Tivic Health

                            Deal Size : $1.5 million

                            Deal Type : Licensing Agreement

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                            09

                            ImmunityBio

                            U.S.A arrow
                            OTS 2025
                            Not Confirmed

                            ImmunityBio

                            U.S.A arrow
                            OTS 2025
                            Not Confirmed
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                            • WHO-GMP
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                            Lead Product(s) : Nogapendekin Alpha Inbakicept,CAR-NK

                            Therapeutic Area : Hematology

                            Study Phase : Phase III

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            ImmunityBio Gets FDA RMAT for ANKTIVA, CAR-NK in Pancreatic Cancer, Lymphopenia

                            Details : Anktiva and CAR-NK combination is being evaluated for the reversal of Lymphopenia in Relapsed Pancreatic Cancer.

                            Product Name : Anktiva

                            Product Type : Protein

                            Upfront Cash : Inapplicable

                            February 27, 2025

                            Lead Product(s) : Nogapendekin Alpha Inbakicept,CAR-NK

                            Therapeutic Area : Hematology

                            Highest Development Status : Phase III

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            10

                            Agios Pharmaceuticals

                            U.S.A arrow
                            OTS 2025
                            Not Confirmed

                            Agios Pharmaceuticals

                            U.S.A arrow
                            OTS 2025
                            Not Confirmed
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                            • EDQM
                            • WHO-GMP
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                            Lead Product(s) : Mitapivat

                            Therapeutic Area : Hematology

                            Study Phase : Phase III

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Agios Receives FDA Acceptance for PYRUKYND® in Thalassemia

                            Details : Pyrukynd (mitapivat sulfate) is a pyruvate kinase activator. It is being developed for adult patients with non-transfusion-dependent and transfusion-dependent alpha- or beta-thalassemia.

                            Product Name : Pyrukynd

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            January 08, 2025

                            Lead Product(s) : Mitapivat

                            Therapeutic Area : Hematology

                            Highest Development Status : Phase III

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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