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    [{"orgOrder":0,"company":"Halia Therapeutics","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"U.S.A","productType":"Other Small Molecule","year":"2024","type":"Inapplicable","leadProduct":"HT-6184","moa":"NEK7","graph1":"Neurology","graph2":"Phase II","graph3":"Halia Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Oral","sponsorNew":"Halia Therapeutics \/ Inapplicable","highestDevelopmentStatusID":"8","companyTruncated":"Halia Therapeutics \/ Inapplicable"},{"orgOrder":0,"company":"Halia Therapeutics","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Other Small Molecule","year":"2024","type":"Inapplicable","leadProduct":"HT-6184","moa":"NEK7","graph1":"Oncology","graph2":"Phase II","graph3":"Halia Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph 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Therapeutics","amount2":0,"highestDevelopmentShortName":"Discovery","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Nasal","sponsorNew":"Halia Therapeutics \/ Halia Therapeutics","highestDevelopmentStatusID":"2","companyTruncated":"Halia Therapeutics \/ Halia Therapeutics"}]

    Find Clinical Drug Pipeline Developments & Deals by Halia Therapeutics

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                            01

                            Halia Therapeutics

                            U.S.A arrow
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                            Halia Therapeutics

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                            Lead Product(s) : HT-6184

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Halia Reports Positive Data and Progresses Phase 2 Trial for HT-6184 in LR-MDS

                            Details : HT-6184 is a first-in-class NLRP3-inhibitor which target the protein NEK7 through an allosteric mechanism. It is under phase 2 clinical development for the treatment of lower-risk myelodysplastic syndromes.

                            Product Name : Undisclosed

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            December 10, 2024

                            Lead Product(s) : HT-6184

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            02

                            Halia Therapeutics

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                            ChemOutsourcing
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                            Halia Therapeutics

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                            ChemOutsourcing
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                            Lead Product(s) : HT-4253

                            Therapeutic Area : Undisclosed

                            Study Phase : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Study to Evaluate HT-4253 in Healthy Subjects

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            August 05, 2024

                            Lead Product(s) : HT-4253

                            Therapeutic Area : Undisclosed

                            Highest Development Status : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

                            Halia Therapeutics

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                            ChemOutsourcing
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                            Halia Therapeutics

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                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Neurology

                            Study Phase : Discovery

                            Recipient : Biolexis Therapeutics

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            Halia and Biolexis Partner To Develop NLRP3 Neuroinflammation Therapy

                            Details : The collaboration successfully identified a novel brain-penetrant small molecule candidate targeting NLRP3-driven neuroinflammation by leveraging Biolexis' MolecuLern™ AI-enabled approach.

                            Product Name : Undisclosed

                            Product Type : Undisclosed

                            Upfront Cash : Undisclosed

                            July 31, 2024

                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Neurology

                            Highest Development Status : Discovery

                            Recipient : Biolexis Therapeutics

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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                            04

                            Halia Therapeutics

                            U.S.A arrow
                            ChemOutsourcing
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                            Halia Therapeutics

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                            ChemOutsourcing
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                            Lead Product(s) : HT-4253

                            Therapeutic Area : Neurology

                            Study Phase : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Halia Therapeutics Announces First Healthy Volunteer Dosed with HT-4253 for Alzheimer’s

                            Details : HT-4253 is a LRRK2 inhibitor, small molecule drug candidate, which is currently being evaluated for the treatment of alzheimer's disease.

                            Product Name : Undisclosed

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            July 10, 2024

                            Lead Product(s) : HT-4253

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            05

                            Halia Therapeutics

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                            ChemOutsourcing
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                            Halia Therapeutics

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                            ChemOutsourcing
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                            Lead Product(s) : HT-4253

                            Therapeutic Area : Neurology

                            Study Phase : Preclinical

                            Recipient : Canary Speech

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            Halia Collaborates with Canary Speech for AI-Driven Therapeutics Development

                            Details : The collaboration utilizes Canary Speech's AI platform to enhance monitoring and treatment of Alzheimer’s, integrating insights to improve the efficacy of HT-4253.

                            Product Name : Undisclosed

                            Product Type : Other Small Molecule

                            Upfront Cash : Undisclosed

                            June 02, 2024

                            Lead Product(s) : HT-4253

                            Therapeutic Area : Neurology

                            Highest Development Status : Preclinical

                            Recipient : Canary Speech

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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                            06

                            Halia Therapeutics

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                            ChemOutsourcing
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                            Halia Therapeutics

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                            ChemOutsourcing
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                            Lead Product(s) : HT-4253

                            Therapeutic Area : Neurology

                            Study Phase : IND Enabling

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Halia Therapeutics to Launch LRRK2 Program for Alzheimer's at Discovery Europe 2024

                            Details : HT-4253 an IND-enabling candidate, targets Leucine-Rich Repeat Kinase 2 (LRRK2) protein, which is a key player in regulating RAB10, a critical factor in the progression of Alzheimer's disease.

                            Product Name : Undisclosed

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            May 14, 2024

                            Lead Product(s) : HT-4253

                            Therapeutic Area : Neurology

                            Highest Development Status : IND Enabling

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            Halia Therapeutics

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                            ChemOutsourcing
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                            Halia Therapeutics

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                            ChemOutsourcing
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                            Lead Product(s) : HT-6184

                            Therapeutic Area : Neurology

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Evaluating Ability of HT-6184 to Reduce Inflammation and Pain After Third Molar Extraction

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            February 05, 2024

                            Lead Product(s) : HT-6184

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            08

                            Halia Therapeutics

                            U.S.A arrow
                            ChemOutsourcing
                            Not Confirmed

                            Halia Therapeutics

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                            ChemOutsourcing
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                            Lead Product(s) : HT-6184

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Halia Therapeutics Dosed its First Patient in Phase 2a Clinical Trial of HT-6184, a First-in-Class NLRP3-Inhib...

                            Details : HT-6184 is a first-in-class NLRP3-inhibitor which target the protein NEK7 through an allosteric mechanism. It is under phase 2 clinical development for the treatment of lower-risk myelodysplastic syndromes.

                            Product Name : Undisclosed

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            December 13, 2023

                            Lead Product(s) : HT-6184

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            09

                            Halia Therapeutics

                            U.S.A arrow
                            ChemOutsourcing
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                            Halia Therapeutics

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                            ChemOutsourcing
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                            Lead Product(s) : HT-6184

                            Therapeutic Area : Neurology

                            Study Phase : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Halia Therapeutics Announces Completion of Enrollment for Phase I Clinical Trial of HT-6184

                            Details : HT-6184 is the first drug candidate to target the protein NEK7 through an allosteric mechanism to inhibit NLRP3 inflammasome activity and it promotes the disassembly of the inflammasome once activated.

                            Product Name : Undisclosed

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            July 08, 2023

                            Lead Product(s) : HT-6184

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            10

                            Halia Therapeutics

                            U.S.A arrow
                            ChemOutsourcing
                            Not Confirmed

                            Halia Therapeutics

                            U.S.A arrow
                            ChemOutsourcing
                            Not Confirmed
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                            Lead Product(s) : HT-6184

                            Therapeutic Area : Undisclosed

                            Study Phase : Phase I

                            Sponsor : TKL Research, Inc.

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Study to Evaluate HT-6184 in Healthy Subjects

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            July 07, 2022

                            Lead Product(s) : HT-6184

                            Therapeutic Area : Undisclosed

                            Highest Development Status : Phase I

                            Sponsor : TKL Research, Inc.

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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