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    [{"orgOrder":0,"company":"Gradalis","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Other Large Molecule","year":"2024","type":"Inapplicable","leadProduct":"GRAD1405","moa":"Undisclosed","graph1":"Oncology","graph2":"Preclinical","graph3":"Gradalis","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Gradalis \/ Inapplicable","highestDevelopmentStatusID":"4","companyTruncated":"Gradalis \/ Inapplicable"},{"orgOrder":0,"company":"Gradalis","sponsor":"CPRIT","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Cell and Gene therapy","year":"2023","type":"Funding","leadProduct":"Gemogenovatucel-T","moa":"GM-CSF","graph1":"Oncology","graph2":"Phase II","graph3":"Gradalis","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intradermal Injection","sponsorNew":"Gradalis \/ CPRIT","highestDevelopmentStatusID":"8","companyTruncated":"Gradalis \/ CPRIT"},{"orgOrder":0,"company":"Gradalis","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Cell and Gene therapy","year":"2022","type":"Inapplicable","leadProduct":"Atezolizumab","moa":"||GM-CSF","graph1":"Oncology","graph2":"Phase II","graph3":"Gradalis","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intradermal Injection","sponsorNew":"Gradalis \/ Inapplicable","highestDevelopmentStatusID":"8","companyTruncated":"Gradalis \/ Inapplicable"},{"orgOrder":0,"company":"Gradalis","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Cell and Gene therapy","year":"2022","type":"Inapplicable","leadProduct":"Atezolizumab","moa":"||GM-CSF","graph1":"Oncology","graph2":"Phase II","graph3":"Gradalis","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intradermal Injection","sponsorNew":"Gradalis \/ Inapplicable","highestDevelopmentStatusID":"8","companyTruncated":"Gradalis \/ Inapplicable"},{"orgOrder":0,"company":"Gradalis","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Cell and Gene therapy","year":"2022","type":"Inapplicable","leadProduct":"Atezolizumab","moa":"||GM-CSF","graph1":"Oncology","graph2":"Phase II","graph3":"Gradalis","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intradermal Injection","sponsorNew":"Gradalis \/ Inapplicable","highestDevelopmentStatusID":"8","companyTruncated":"Gradalis \/ Inapplicable"},{"orgOrder":0,"company":"Gradalis","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Cell and Gene therapy","year":"2025","type":"Inapplicable","leadProduct":"Gemogenovatucel-T","moa":"GM-CSF","graph1":"Oncology","graph2":"Phase II","graph3":"Gradalis","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intradermal Injection","sponsorNew":"Gradalis \/ Inapplicable","highestDevelopmentStatusID":"8","companyTruncated":"Gradalis \/ Inapplicable"}]

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                            01

                            Gradalis

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                            Lead Product(s) : Gemogenovatucel-T

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Gradalis Gets FDA RMAT for Vigil® Immunotherapy in Advanced Ovarian Cancer

                            Details : Vigil (gemogenovatucel-T) a novel, triple function immunotherapy platform that modifies patient’s tumor by using bi-shRNA to reduce furin, being investigated for advanced Stage IIIb/IV ovarian cancer.

                            Product Name : Vigil

                            Product Type : Cell and Gene therapy

                            Upfront Cash : Inapplicable

                            February 05, 2025

                            Lead Product(s) : Gemogenovatucel-T

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            02

                            Gradalis

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                            Lead Product(s) : GRAD1405

                            Therapeutic Area : Oncology

                            Study Phase : Preclinical

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Gradalis' GRAD1405 Shows Positive Impact on KRAS Mutations in Resistant Cancers

                            Details : GRAD1405 utilizes Gradalis’ gene silencing bi-shRNAi technology to reduce mutated KRAS gene expression, under preclinical development for drug-resistant lung, colon, and pancreatic cancers.

                            Product Name : GRAD1405

                            Product Type : Other Large Molecule

                            Upfront Cash : Inapplicable

                            April 01, 2024

                            Lead Product(s) : GRAD1405

                            Therapeutic Area : Oncology

                            Highest Development Status : Preclinical

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

                            Gradalis

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                            Lead Product(s) : Gemogenovatucel-T

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : CPRIT

                            Deal Size : $9.9 million

                            Deal Type : Funding

                            DEALS_DEV arrow-down

                            Gradalis Awarded $9.9 Million Grant from the Cancer Prevention and Research Institute of Texas

                            Details : The funds will be used to support the company's Phase 2 clinical study of Vigil (FANG vaccine), a novel, triple function immunotherapy platform, in platinum-sensitive patients who have recurrent ovarian cancer.

                            Product Name : Vigil

                            Product Type : Cell and Gene therapy

                            Upfront Cash : Undisclosed

                            November 16, 2023

                            Lead Product(s) : Gemogenovatucel-T

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : CPRIT

                            Deal Size : $9.9 million

                            Deal Type : Funding

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                            04

                            Gradalis

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                            Lead Product(s) : Gemogenovatucel-T,Atezolizumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Gradalis Receives Clearance to Begin Pivotal Phase 3 Clinical Trial of Vigil® (gemogenovatucel-T) in Patients...

                            Details : Vigil® (gemogenovatucel-T) is a novel, personalized immunotherapy platform designed to achieve a Trifecta of immune anticancer activity using a unique bi-shRNA DNA-based plasmid and the patient's own tumor tissue.

                            Product Name : Vigil

                            Product Type : Cell and Gene therapy

                            Upfront Cash : Inapplicable

                            December 21, 2022

                            Lead Product(s) : Gemogenovatucel-T,Atezolizumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            05

                            Gradalis

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                            Lead Product(s) : Gemogenovatucel-T,Atezolizumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Gradalis to Host Key Opinion Leader Webinar on Unmet Medical Needs in Ovarian Cancer and the Company’s Immun...

                            Details : Vigil® (gemogenovatucel-T) is a novel, personalized immunotherapy platform designed to achieve a Trifecta of immune anticancer activity using a unique bi-shRNA DNA based plasmid and the patient’s own tumor tissue.

                            Product Name : Vigil

                            Product Type : Cell and Gene therapy

                            Upfront Cash : Inapplicable

                            September 28, 2022

                            Lead Product(s) : Gemogenovatucel-T,Atezolizumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            06

                            Gradalis

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                            Lead Product(s) : Gemogenovatucel-T,Atezolizumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Gradalis Announces Publication in Nature Communications Medicine Identifying Survival Predicting Biomarker in ...

                            Details : Vigil (gemogenovatucel-T) is a novel, plasmid engineered, autologous tumor cell immunotherapy platform designed to achieve a trifecta of immune anticancer activity using a unique bi-shRNA DNA based technology and the patient’s own tumor tissue.

                            Product Name : Vigil

                            Product Type : Cell and Gene therapy

                            Upfront Cash : Inapplicable

                            August 29, 2022

                            Lead Product(s) : Gemogenovatucel-T,Atezolizumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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