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Find Clinical Drug Pipeline Developments & Deals by Generate Biomedicines

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            Details:

            The collaboration aims to discover and develop chimeric antigen receptor (CAR) T-cell therapies, and armoring technologies, for up to three oncology targets, including in ovarian cancer and other solid tumors.

            Lead Product(s): CAR T-Cell Therapy

            Therapeutic Area: Oncology Product Name: Undisclosed

            Highest Development Status: Discovery Product Type: Cell and Gene therapy

            Partner/Sponsor/Collaborator: Roswell Park Comprehensive Cancer Center

            Deal Size: Undisclosed Upfront Cash: Undisclosed

            Deal Type: Collaboration November 01, 2023

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            The financing will be used to advance company's Generative AI pipeline of preclinical and clinical protein therapeutics, including GB-0669, a monoclonal antibody targeting a highly conserved region of the spike protein, in SARS-CoV-2.

            Lead Product(s): GB-0669

            Therapeutic Area: Infections and Infectious Diseases Product Name: GB-0669

            Highest Development Status: Phase I Product Type: Large molecule

            Partner/Sponsor/Collaborator: Amgen Inc

            Deal Size: $273.0 million Upfront Cash: Undisclosed

            Deal Type: Series C Financing September 14, 2023

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            The collaboration aims to jointly discover and co-develop protein therapeutics for up to 5 oncology targets in advanced cancers, including small-cell and NSCLC. The agreement combines Generate:Biomedicines’ The Generate Platform with MD Anderson’s clinical research expertise.

            Lead Product(s): Undisclosed

            Therapeutic Area: Oncology Product Name: Undisclosed

            Highest Development Status: Discovery Product Type: Undisclosed

            Partner/Sponsor/Collaborator: The University of Texas MD Anderson Cancer Center

            Deal Size: Undisclosed Upfront Cash: Undisclosed

            Deal Type: Collaboration April 27, 2023

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            Generate Biomedicine's integrated in silico design and wet lab capabilities combined with Amgen to harness its machine-learning-enabled technology to discover and develop protein therapeutics for five clinical targets across a range of therapeutic areas and modalities.

            Lead Product(s): Engineered Protein-based Therapy

            Therapeutic Area: Technology Product Name: Undisclosed

            Highest Development Status: Discovery Platform Product Type: Large molecule

            Partner/Sponsor/Collaborator: Amgen Inc

            Deal Size: $1,900.0 million Upfront Cash: $50.0 million

            Deal Type: Collaboration January 06, 2022

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