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    [{"orgOrder":0,"company":"Gate Neurosciences","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Psychiatry\/Psychology","country":"U.S.A","productType":"Miscellaneous","year":"2022","type":"Inapplicable","leadProduct":"Apimostinel","moa":"Glutamate [NMDA] receptor","graph1":"Psychiatry\/Psychology","graph2":"Phase II","graph3":"Gate Neurosciences","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Psychiatry","amount2New":0,"dosageForm":"Infusion","sponsorNew":"Gate Neurosciences \/ Undisclosed","highestDevelopmentStatusID":"8","companyTruncated":"Gate Neurosciences \/ Undisclosed"},{"orgOrder":0,"company":"Gate Neurosciences","sponsor":"The University of Pittsburgh School of Medicine","pharmaFlowCategory":"D","therapeuticArea":"Psychiatry\/Psychology","country":"U.S.A","productType":"Miscellaneous","year":"2024","type":"Collaboration","leadProduct":"Apimostinel","moa":"Glutamate [NMDA] 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Platform","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Gate Neurosciences \/ Gate Neurosciences","highestDevelopmentStatusID":"3","companyTruncated":"Gate Neurosciences \/ Gate Neurosciences"},{"orgOrder":0,"company":"Gate Neurosciences","sponsor":"Rebecca Price","pharmaFlowCategory":"DU","therapeuticArea":"Psychiatry\/Psychology","country":"U.S.A","productType":"Miscellaneous","year":"2024","type":"Inapplicable","leadProduct":"Apimostinel","moa":"Glutamate [NMDA] receptor","graph1":"Psychiatry\/Psychology","graph2":"Phase II","graph3":"Gate Neurosciences","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Psychiatry","amount2New":0,"dosageForm":"Injection","sponsorNew":"Gate Neurosciences \/ Rebecca Price","highestDevelopmentStatusID":"8","companyTruncated":"Gate Neurosciences \/ Rebecca Price"}]

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                            01

                            Gate Neurosciences

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                            Gate Neurosciences

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                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Neurology

                            Study Phase : Discovery Platform

                            Recipient : Boost Neuroscience

                            Deal Size : Undisclosed

                            Deal Type : Acquisition

                            DEALS_DEV arrow-down

                            Gate Neurosciences Focuses on Synapse with Boost Neuroscience Acquisition

                            Details : Acquisition of Boost deepens Gate’s leadership in synapse science and R&D for the development of novel therapeutics that address synaptopathies, or CNS diseases driven by synapse loss and dysfunction.

                            Product Name : Undisclosed

                            Product Type : Undisclosed

                            Upfront Cash : Undisclosed

                            February 19, 2025

                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Neurology

                            Highest Development Status : Discovery Platform

                            Recipient : Boost Neuroscience

                            Deal Size : Undisclosed

                            Deal Type : Acquisition

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                            02

                            Gate Neurosciences

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                            ISPE Annual Meeting
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                            Gate Neurosciences

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                            ISPE Annual Meeting
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                            Lead Product(s) : Apimostinel

                            Therapeutic Area : Psychiatry/Psychology

                            Study Phase : Phase II

                            Sponsor : The University of Pittsburgh School of Medicine

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            Gate Neurosciences, Pittsburgh Partner for Apimostinel Digital Depression Trial

                            Details : The collaboration aims the initiation of a Phase 2 to assess the potential for extending the efficacy of GATE-202 (apimostinel), a rapid-acting antidepressant drug.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Undisclosed

                            December 03, 2024

                            Lead Product(s) : Apimostinel

                            Therapeutic Area : Psychiatry/Psychology

                            Highest Development Status : Phase II

                            Sponsor : The University of Pittsburgh School of Medicine

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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                            03

                            Gate Neurosciences

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                            ISPE Annual Meeting
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                            Gate Neurosciences

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                            Lead Product(s) : Zelquistinel

                            Therapeutic Area : Psychiatry/Psychology

                            Study Phase : Phase II

                            Sponsor : Worldwide Clinical Trials

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            GATE-251 or Placebo for the Reduction of Symptoms of Major Depressive Disorder

                            Details : Zelquistinel is a Other Small Molecule drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Depressive Disorder, Major.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            August 09, 2024

                            Lead Product(s) : Zelquistinel

                            Therapeutic Area : Psychiatry/Psychology

                            Highest Development Status : Phase II

                            Sponsor : Worldwide Clinical Trials

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            04

                            Gate Neurosciences

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                            ISPE Annual Meeting
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                            Gate Neurosciences

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                            ISPE Annual Meeting
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                            Lead Product(s) : Apimostinel

                            Therapeutic Area : Psychiatry/Psychology

                            Study Phase : Phase II

                            Sponsor : Rebecca Price

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Apimostinel + Automated Neurocognitive Training for Depression

                            Details : Apimostinel is a Other Small Molecule drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Depression.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            May 06, 2024

                            Lead Product(s) : Apimostinel

                            Therapeutic Area : Psychiatry/Psychology

                            Highest Development Status : Phase II

                            Sponsor : Rebecca Price

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            05

                            Gate Neurosciences

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                            ISPE Annual Meeting
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                            Gate Neurosciences

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                            ISPE Annual Meeting
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                            Lead Product(s) : Zelquistinel

                            Therapeutic Area : Psychiatry/Psychology

                            Study Phase : Phase II

                            Sponsor : Beacon Biosignals

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            Gate Neurosciences Partners with Beacon Biosignals on EEG Biomarkers for Depression

                            Details : Beacon's Dreem™ 3S headband will be used to analyze EEG and sleep in depressed patients during Phase 2 trials of zelquistinel, an NMDA receptor modulator.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Undisclosed

                            January 24, 2024

                            Lead Product(s) : Zelquistinel

                            Therapeutic Area : Psychiatry/Psychology

                            Highest Development Status : Phase II

                            Sponsor : Beacon Biosignals

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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                            06

                            Gate Neurosciences

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                            ISPE Annual Meeting
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                            Gate Neurosciences

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                            Lead Product(s) : Apimostinel

                            Therapeutic Area : Psychiatry/Psychology

                            Study Phase : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Gate Neurosciences Doses First Subject in a Translational EEG Biomarker Study of Apimostinel, a Rapid-Acting T...

                            Details : GATE-202 (apimostinel) is 2nd generation rapid-acting injectable NMDAR modulator program. Previously demonstrated rapid and robust 24-hour antidepressant effects in a Phase 2a MDD study (p=0.0034)

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            November 29, 2022

                            Lead Product(s) : Apimostinel

                            Therapeutic Area : Psychiatry/Psychology

                            Highest Development Status : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            Gate Neurosciences

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                            ISPE Annual Meeting
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                            Gate Neurosciences

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                            ISPE Annual Meeting
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                            Lead Product(s) : Apimostinel

                            Therapeutic Area : Psychiatry/Psychology

                            Study Phase : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Multiple Ascending Dose and Electroencephalography Trial of GATE-202 in Healthy Volunteers

                            Details : Apimostinel is a Other Small Molecule drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Depressive Disorder, Major.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            October 28, 2022

                            Lead Product(s) : Apimostinel

                            Therapeutic Area : Psychiatry/Psychology

                            Highest Development Status : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            08

                            Gate Neurosciences

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                            ISPE Annual Meeting
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                            Gate Neurosciences

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                            Lead Product(s) : GATE-101

                            Therapeutic Area : Psychiatry/Psychology

                            Study Phase : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Safety and Tolerability of Single and Multiple Ascending Doses of GATE-101 in Normal Human Volunteers

                            Details : GATE-101 is a drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Depressive Disorder, Major.

                            Product Name : Undisclosed

                            Product Type : Undisclosed

                            Upfront Cash : Inapplicable

                            November 05, 2020

                            Lead Product(s) : GATE-101

                            Therapeutic Area : Psychiatry/Psychology

                            Highest Development Status : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            09

                            Gate Neurosciences

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                            ISPE Annual Meeting
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                            Gate Neurosciences

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                            Lead Product(s) : Zelquistinel

                            Therapeutic Area : Psychiatry/Psychology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            AGN-241751 in the Treatment of Major Depressive Disorder

                            Details : AGN-241751 is a Other Small Molecule drug candidate, which is currently being evaluated in phase I/ phase II clinical studies for the treatment of Depressive Disorder, Major.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            October 31, 2018

                            Lead Product(s) : Zelquistinel

                            Therapeutic Area : Psychiatry/Psychology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            10

                            Gate Neurosciences

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                            Lead Product(s) : Zelquistinel

                            Therapeutic Area : Psychiatry/Psychology

                            Study Phase : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            AGN-241751 in the Treatment of Major Depressive Disorder

                            Details : AGN-241751 is a Other Small Molecule drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Depressive Disorder, Major.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            July 13, 2018

                            Lead Product(s) : Zelquistinel

                            Therapeutic Area : Psychiatry/Psychology

                            Highest Development Status : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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