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    [{"orgOrder":0,"company":"Frontier Medicine","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Miscellaneous","year":"2024","type":"Inapplicable","leadProduct":"FMC-376","moa":"GTP-bound","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Frontier Medicine","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Capsule","sponsorNew":"Frontier Medicine \/ Undisclosed","highestDevelopmentStatusID":"7","companyTruncated":"Frontier Medicine \/ Undisclosed"},{"orgOrder":0,"company":"Frontier Medicine","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Miscellaneous","year":"2023","type":"Inapplicable","leadProduct":"FMC-376","moa":"GTP-bound","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Frontier Medicine","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Capsule","sponsorNew":"Frontier Medicine \/ Undisclosed","highestDevelopmentStatusID":"7","companyTruncated":"Frontier Medicine \/ Undisclosed"},{"orgOrder":0,"company":"Frontier Medicine","sponsor":"Deep Track Capital","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Miscellaneous","year":"2024","type":"Series C Financing","leadProduct":"FMC-376","moa":"GTP-bound","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Frontier Medicine","amount2":0.10000000000000001,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0.10000000000000001,"dosageForm":"Capsule","sponsorNew":"Frontier Medicine \/ Deep Track Capital","highestDevelopmentStatusID":"7","companyTruncated":"Frontier Medicine \/ Deep Track Capital"},{"orgOrder":0,"company":"Frontier Medicine","sponsor":"Deerfield 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Medicine","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Frontier Medicine \/ Undisclosed","highestDevelopmentStatusID":"4","companyTruncated":"Frontier Medicine \/ Undisclosed"},{"orgOrder":0,"company":"Frontier Medicine","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Undisclosed","year":"2022","type":"Inapplicable","leadProduct":"Undisclosed","moa":"Undisclosed","graph1":"Oncology","graph2":"Preclinical","graph3":"Frontier Medicine","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Frontier Medicine \/ Undisclosed","highestDevelopmentStatusID":"4","companyTruncated":"Frontier Medicine \/ Undisclosed"},{"orgOrder":0,"company":"Frontier Medicine","sponsor":"AbbVie Inc","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Undisclosed","year":"2020","type":"Collaboration","leadProduct":"Undisclosed","moa":"Undisclosed","graph1":"Oncology","graph2":"Preclinical","graph3":"Frontier Medicine","amount2":1.1000000000000001,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":1.1000000000000001,"dosageForm":"Undisclosed","sponsorNew":"Frontier Medicine \/ AbbVie Inc","highestDevelopmentStatusID":"4","companyTruncated":"Frontier Medicine \/ AbbVie Inc"},{"orgOrder":0,"company":"Frontier Medicine","sponsor":"AbbVie Inc","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Undisclosed","year":"2023","type":"Partnership","leadProduct":"Undisclosed","moa":"Undisclosed","graph1":"Oncology","graph2":"Preclinical","graph3":"Frontier Medicine","amount2":1,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":1,"dosageForm":"Undisclosed","sponsorNew":"Frontier Medicine \/ AbbVie Inc","highestDevelopmentStatusID":"4","companyTruncated":"Frontier Medicine \/ AbbVie Inc"},{"orgOrder":0,"company":"Frontier Medicine","sponsor":"AbbVie Inc","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Undisclosed","year":"2024","type":"Partnership","leadProduct":"Undisclosed","moa":"Undisclosed","graph1":"Oncology","graph2":"Preclinical","graph3":"Frontier Medicine","amount2":1,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":1,"dosageForm":"Undisclosed","sponsorNew":"Frontier Medicine \/ AbbVie Inc","highestDevelopmentStatusID":"4","companyTruncated":"Frontier Medicine \/ AbbVie Inc"},{"orgOrder":0,"company":"Frontier Medicine","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Miscellaneous","year":"2025","type":"Inapplicable","leadProduct":"FMC-242","moa":"PI3K-alpha | RAS","graph1":"Oncology","graph2":"Discovery","graph3":"Frontier Medicine","amount2":0,"highestDevelopmentShortName":"Discovery","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Frontier Medicine \/ Undisclosed","highestDevelopmentStatusID":"2","companyTruncated":"Frontier Medicine \/ Undisclosed"}]

    Find Clinical Drug Pipeline Developments & Deals by Frontier Medicine

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                            01

                            Frontier Medicine

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                            Frontier Medicine

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                            Lead Product(s) : FMC-242

                            Therapeutic Area : Oncology

                            Study Phase : Discovery

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Frontier Medicines Reveals Third Precision Oncology Candidate

                            Details : FMC-242, a miscellaneous product targeting PI3K-alpha and RAS, shows promise in treating cancer.

                            Product Name : FMC-242

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            October 14, 2025

                            Lead Product(s) : FMC-242

                            Therapeutic Area : Oncology

                            Highest Development Status : Discovery

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            02

                            Frontier Medicine

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                            AIChE Annual Meeting
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                            AIChE Annual Meeting
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                            Lead Product(s) : FMC-220

                            Therapeutic Area : Oncology

                            Study Phase : Preclinical

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Frontier Medicines Announces FMC-220, First p53 Y220C Activator Development

                            Details : FMC-220 is a highly selective, covalent small molecule activator, beinf investigated for patients with tumors harboring an important mutant of p53.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            January 09, 2025

                            Lead Product(s) : FMC-220

                            Therapeutic Area : Oncology

                            Highest Development Status : Preclinical

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

                            Frontier Medicine

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                            AIChE Annual Meeting
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                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Oncology

                            Study Phase : Preclinical

                            Sponsor : AbbVie Inc

                            Deal Size : $1,000.0 million

                            Deal Type : Partnership

                            DEALS_DEV arrow-down

                            Frontier Announces Milestone Payment in AbbVie Partnership for Advancing Lead Candidates

                            Details : Under the partnership, the companies will collaborate on the research and pre-clinical development of programs directed to novel E3 ligases, and certain immunology and oncology targets.

                            Product Name : Undisclosed

                            Product Type : Undisclosed

                            Upfront Cash : Undisclosed

                            July 23, 2024

                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Oncology

                            Highest Development Status : Preclinical

                            Sponsor : AbbVie Inc

                            Deal Size : $1,000.0 million

                            Deal Type : Partnership

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                            04

                            Frontier Medicine

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                            AIChE Annual Meeting
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                            AIChE Annual Meeting
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                            Lead Product(s) : FMC-376

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Deep Track Capital

                            Deal Size : $100.0 million

                            Deal Type : Series C Financing

                            DEALS_DEV arrow-down

                            Frontier Medicines Appoints Gerardo Ubaghs as CFO, Announces $20M Series C Extension

                            Details : The financing proceeds will support further advancement of Frontier’s FMC-376, a small molecule. Currently, it is being evaluated for the treatment of advanced solid tumors With KRAS G12C mutations.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Undisclosed

                            June 25, 2024

                            Lead Product(s) : FMC-376

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Deep Track Capital

                            Deal Size : $100.0 million

                            Deal Type : Series C Financing

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                            05

                            Frontier Medicine

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                            AIChE Annual Meeting
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                            Lead Product(s) : FMC-376

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Deerfield Management

                            Deal Size : $80.0 million

                            Deal Type : Financing

                            DEALS_DEV arrow-down

                            Frontier Medicines Announces Oversubscribed Series C Financing

                            Details : The financing proceeds will support the advancement of multiple wholly-owned pipeline programs into clinical studies, including FMC-376 for advanced solid tumors with KRAS G12C Mutations.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Undisclosed

                            February 22, 2024

                            Lead Product(s) : FMC-376

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Deerfield Management

                            Deal Size : $80.0 million

                            Deal Type : Financing

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                            06

                            Frontier Medicine

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                            Lead Product(s) : FMC-376

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            A Study Evaluating FMC-376 in Participants With KRAS G12C Mutated Solid Tumors

                            Details : FMC-376 is a Other Small Molecule drug candidate, which is currently being evaluated in phase I/ phase II clinical studies for the treatment of Neoplasms.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            February 06, 2024

                            Lead Product(s) : FMC-376

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            Frontier Medicine

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                            Lead Product(s) : FMC-376

                            Therapeutic Area : Oncology

                            Study Phase : IND Enabling

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Frontier Medicines Advances First Development Candidate, FMC-376, a Uniquely Differentiated Inhibitor of Both ...

                            Details : In preclinical studies, FMC-376 retains potency in the context of receptor tyrosine kinase activation, which is likely a major mechanism of non-response and resistance to prior generation inhibitors that only target inactive (GDP-bound) KRASG12C.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            January 05, 2023

                            Lead Product(s) : FMC-376

                            Therapeutic Area : Oncology

                            Highest Development Status : IND Enabling

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            08

                            Frontier Medicine

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                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Oncology

                            Study Phase : Discovery

                            Sponsor : AbbVie Inc

                            Deal Size : $1,000.0 million

                            Deal Type : Partnership

                            DEALS_DEV arrow-down

                            Frontier Medicines Announces Advancement of Second and Third Programs Under Global Partnership with AbbVie

                            Details : Under the partnership, Frontier Medicine and Abbvie will collaborate on the research and pre-clinical development of programs directed to novel E3 ligases, and certain immunology and oncology targets.

                            Product Name : Undisclosed

                            Product Type : Undisclosed

                            Upfront Cash : Undisclosed

                            January 05, 2023

                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Oncology

                            Highest Development Status : Discovery

                            Sponsor : AbbVie Inc

                            Deal Size : $1,000.0 million

                            Deal Type : Partnership

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                            09

                            Frontier Medicine

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                            AIChE Annual Meeting
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                            Frontier Medicine

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                            AIChE Annual Meeting
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                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Oncology

                            Study Phase : Preclinical

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Frontier Medicines Announces Oral Presentation on Dual-Acting Inhibitors of the Active and Inactive Forms of K...

                            Details : The study was conducted in preclinical models that are both sensitive (NCI-H358 and MIA PaCa-2) and resistant (NCI-H2122) to first-generation KRASG12C inhibitors (adagrasib and sotorasib). While first-generation inhibitors were less effective in the NCI-...

                            Product Name : Undisclosed

                            Product Type : Undisclosed

                            Upfront Cash : Inapplicable

                            March 09, 2022

                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Oncology

                            Highest Development Status : Preclinical

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            10

                            Frontier Medicine

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                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Oncology

                            Study Phase : Discovery

                            Sponsor : AbbVie Inc

                            Deal Size : $1,100.0 million

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            AbbVie and Frontier Medicines Ink Global Partnership to Develop Novel Therapies and E3 Degraders Against Diffi...

                            Details : Under the multi-year collaboration, AbbVie and Frontier will utilize Frontier's proprietary chemoproteomics platform to identify small molecules for programs directed to novel E3 ligases and certain oncology and immunology targets.

                            Product Name : Undisclosed

                            Product Type : Undisclosed

                            Upfront Cash : $55.0 million

                            December 02, 2020

                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Oncology

                            Highest Development Status : Discovery

                            Sponsor : AbbVie Inc

                            Deal Size : $1,100.0 million

                            Deal Type : Collaboration

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