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Find Clinical Drug Pipeline Developments & Deals by Foundation Medicine
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The collaboration aims to develop the FoundationOne Heme platform as a companion diagnostic to identify patients with AML with a NPM1 mutations for potential treatment with DSP-5336 (enzomenib).
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Ojemda (tovorafenib) is a a type II RAF inhibitor small molecule drug candidate. It is approved for the treatment of R/R pediatric low-grade glioma (pLGG) in patients 6 months of age and older.
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Tepmetko (tepotinib) is a kinase inhibitor indicated for the treatment of adult patients with NSCLC harboring mesenchymalepithelial transition (MET) exon 14 skipping alterations.
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FoundationOne®Liquid CDx to be used as a companion diagnostic for Itovebi (inavolisib) for adults with endocrine-resistant, PIK3CA-mutated HR+/HER2-breast Cancer.
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Lynparza (olaparib) in combination with abiraterone and prednisone or prednisolone indicated for the treatment of adult patients with BRCA-mutated metastatic castration-resistant prostate cancer.
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The collaboration aims to develop Foundation Medicine’s RNA platform as a companion diagnostic for Merus’s bispecific antibody MCLA-128 (zenocutuzumab) to treat neuregulin 1 fusion cancer.
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Akeega (niraparib, abiraterone acetate) is a tablet works by inhibiting approved for BRCA-mutated mCRPC in adults. The FDA has approved FoundationOne Liquid CDx as its companion diagnostic.
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The collaboration aims to support Repare’s ongoing clinical development of RP-6306 (lunresertib) oral small molecule inhibitor of PKMYT1 alone or with camonsertib for the treatment of neoplasms.
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The partnership aims to impact the care of patients with late-stage colorectal cancer undergoing surgery in a Phase II trial assessing QBECO SSI in reducing post-operative immune suppression.
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The partnership aims to develop Foundation Medicine’s FoundationOne®CDx, as a companion diagnostic for PMV’s PC14586 (rezatapopt), a first-in-class therapy for solid tumors with TP53 Y220C mutation.
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